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2012-01-01Zeitschriftenartikel
Chronic wasting disease: Fingerprinting the culprit in risk assessments 
Daus, Martin L.; Beekes, Michael
Transmissible spongiform encephalopathies (prion diseases) in animals may be associated with a zoonotic risk potential for humans as shown by the occurrence of variant Creutzfeldt-Jakob disease in the wake of the bovine ...
2011-06-12Zeitschriftenartikel
Pattern of seroreactivity against feline foamy virus proteins in domestic cats from Germany 
Bleiholder, Anne; Mühle, Michael; Hechler, Torsten; Bevins, Sarah; vandeWoude, Sue; Denner, Joachim; Löchelt, Martin
The prevalence of feline foamy virus (FFV, spumaretrovirinae) in naturally infected domestic cats ranges between 30 and 80% FFV positive animals depending on age, sex and geographical region analyzed. Two serotypes have ...
2011-09-03Zeitschriftenartikel
Second external quality assessment of the molecular diagnostic of West Nile virus: Are there improvements towards the detection of WNV? 
Linke, Sonja; MacKay, William G.; Scott, Calum; Wallace, Paul; Niedrig, Matthias
Background: WNV epidemics occur worldwide, new WNV isolates were isolated in southern-east Europe belonging to WNV lineage 2. A first international proficiency study on WNV indicted that some laboratories were not able ...
2011-09-03Zeitschriftenartikel
Medical importance of Sindbis virus in south-west Germany 
Jöst, Hanna; Bürck-Kammerer, Simone; Hütter, Gero; Lattwein, Erik; Lederer, Sabine; Litzba, Nadine; Bock-Hensley, Oswinde; Emmerich, Petra; Günther, Stephan; Becker, Norbert; Niedrig, Matthias; Schmidt-Chanasit, Jonas
2011-05-10Zeitschriftenartikel
Neue Empfehlungen für die Umgebungsuntersuchungen bei Tuberkulose 
Diel, Roland; Loytved, Gunther; Nienhaus, Albert; Castell, S.; Detjen, A.; Geerdes-Fenge, H.; Haas, Walter; Hauer, Barbara; Königstein, B.; Maffei, D.; Magdorf, Klaus; Priwitzer, M.; Zellweger, J.-P.; Loddenkemper, Robert
Nach der Einführung der neuen Interferon-γ-Release Assays (IGRAs) in den Empfehlungen des Deutschen Zentralkomitees zur Bekämpfung der Tuberkulose im Jahre 2007 hat sich die Datenlage für deren Einsatz beträchtlich verbessert. ...
2012-05-31Zeitschriftenartikel
Prospective hospital-based case–control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009–2010 using matched hospital and test-negative controls 
Hellenbrand, Wiebke; Jorgensen, Pernille; Schweiger, Brunhilde; Falkenhorst, Gerhard; Nachtnebel, Matthias; Greutélaers, Benedikt; Traeder, Christian; Wichmann, Ole
Background: We performed a case–control study to estimate vaccine effectiveness (VE) for prevention of hospitalization due to pandemic influenza A(H1N1)pdm09 (pH1N1) and to identify risk factors for pH1N1 and acute ...
2012-08-30Zeitschriftenartikel
Evidence for airborne infectious disease transmission in public ground transport – a literature review 
Mohr, Oliver; Askar, Mona; Schink, Susanne; Eckmanns, Tim; Krause, Gérard; Poggensee, Gabriele
While guidelines on contact tracing (CT) after exposure to certain infectious pathogens during air travel exist, no guidance documents are available on CT in response to potential exposure on public ground transport. We ...
2011-05-31Zeitschriftenartikel
Improvement of H5N1 influenza vaccine viruses: Influence of internal gene segments of avian and human origin on production and hemagglutinin content 
Abt, Marion; Jonge, Jørgen de; Laue, Michael; Wolff, Thorsten
The H5N1-clade 1 influenza vaccine strain NIBRG-14 produces exceptionally low amounts of antigen, a problem recently encountered also for initial pandemic H1N1-2009 vaccine seeds. Here, we report on a strategy that may ...
2012-08-31Zeitschriftenartikel
Metagenomic abundance estimation and diagnostic testing on species level 
Lindner, Martin S.; Renard, Bernhard Y.
One goal of sequencing-based metagenomic community analysis is the quantitative taxonomic assessment of microbial community compositions. In particular, relative quantification of taxons is of high relevance for metagenomic ...
2012-01-30Zeitschriftenartikel
Emergence of OXA-48-type carbapenemase-producing Enterobacteriaceae in German hospitals 
Pfeifer, Yvonne; Schlatterer, Kathrin; Engelmann, Elisabeth; Schiller, Reinhold A.; Frangenberg, Hans Reiner; Stiewe, Doris; Holfelder, Martin; Witte, Wolfgang; Nordmann, Patrice; Poirel, Laurent
Nine carbapenem-resistant Enterobacteriaceae isolates collected from eight patients in five German hospitals were investigated. Six isolates produced the OXA-48 carbapenemase, and three isolates produced OXA-162, which is ...
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