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2018-11-15Zeitschriftenartikel
Molecular Genetic and Functional Analysis of pks-Harboring, Extra-Intestinal Pathogenic Escherichia coli From India 
Suresh, Arya; Ranjan, Amit; Jadhav, Savita; Hussain, Arif; Shaik, Sabiha; Alam, Munirul; Baddam, Ramani; Wieler, Lothar H.; Ahmed, Niyaz
Colibactin, a genotoxin, encoded by the pks pathogenicity island of Escherichia coli belonging to the B2 phylogroup has been reported as a determinant of bacterial pathogenicity. The present study was carried out to detect ...
2018-10-08Zeitschriftenartikel
Parasitic Nematodes Exert Antimicrobial Activity and Benefit From Microbiota-Driven Support for Host Immune Regulation 
Rausch, Sebastian; Midha, Ankur; Kuhring, Matthias; Affinass, Nicole; Radonic, Aleksandar; Kühl, Anja A.; Bleich, André; Renard, Bernhard Y.; Hartmann, Susanne
Intestinal parasitic nematodes live in intimate contact with the host microbiota. Changes in the microbiome composition during nematode infection affect immune control of the parasites and shifts in the abundance of bacterial ...
2018-12-05Zeitschriftenartikel
Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence 
Lang, Christina; Fruth, Angelika; Holland, Gudrun; Laue, Michael; Mühlen, Sabrina; Dersch, Petra; Flieger, Antje
A large German outbreak in 2011 was caused by a locus of enterocyte effacement (LEE)-negative enterohemorrhagic E. coli (EHEC) strain of the serotype O104:H4. This strain harbors markers that are characteristic of both ...
2018-10-24Zeitschriftenartikel
Equine Methicillin-Resistant Sequence Type 398 Staphylococcus aureus (MRSA) Harbor Mobile Genetic Elements Promoting Host Adaptation 
Walther, Birgit; Klein, Katja-Sophia; Barton, Ann-Kristin; Semmler, Torsten; Huber, Charlotte; Merle, Roswitha; Tedin, Karsten; Mitrach, Franziska; Lübke-Becker, Antina; Gehlen, Heidrun
Continuing introduction of multi-drug resistant, zoonotic pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) in horse clinics challenges the biosafety of employees and animal patients. This study was aimed ...
2018-11-14Zeitschriftenartikel
The importance of adjusting for enterococcus species when assessing the burden of vancomycin resistance: a cohort study including over 1000 cases of enterococcal bloodstream infections 
Kramer, Tobias Siegfried; Remschmidt, Cornelius; Werner, Sven; Behnke, Michael; Schwab, Frank; Werner, Guido; Gastmeier, Petra; Leistner, Rasmus
Background: Infections caused by vancomycin-resistant enterococci (VRE) are on the rise worldwide. Few studies have tried to estimate the mortality burden as well as the financial burden of those infections and found ...
2018-11-16Zeitschriftenartikel
Immunogenicity of anthrax recombinant peptides and killed spores in goats and protective efficacy of immune sera in A/J mouse model 
Ndumnego, Okechukwu C.; Koehler, Susanne M.; Crafford, Jannie E.; Beyer, Wolfgang; van Heerden, Henriette
Anthrax is primarily recognized as an affliction of herbivores with incubation period ranging from three to five days post-infection. Currently, the Sterne live-spore vaccine is the only vaccine approved for control of the ...
2018-10-23Zeitschriftenartikel
A new hepatitis E virus genotype 2 strain identified from an outbreak in Nigeria, 2017 
Wang, Bo; Akanbi, Olusola Anuoluwapo; Harms, Dominik; Adesina, Olufisayo; Osundare, Folakemi Abiodun; Naidoo, Dhamari; Deveaux, Isabel; Ogundiran, Opeayo; Ugochukwu, Uzoma; Mba, Nwando; Ihekweazu, Chikwe; Bock, Thomas
Background: In 2017 the Nigerian Ministry of Health notified the World Health Organization (WHO) of an outbreak of hepatitis E located in the north-east region of the country with 146 cases with 2 deaths. The analysis ...
2019-01-03Zeitschriftenartikel
Wahrscheinlicher Fall einer Reinfektion durch Legionella pneumophila 
Buchholz, Udo; Reber, Franziska; Lehfeld, Ann-Sophie; Brodhun, Bonita; Haas, Walter; Schaefer, Benedikt; Stemmler, Fabian; Förster, Christina; Gagell, Corinna; Lück, Christian; Gamradt, Ronny; Heinig, Maxi; Meisel, Christian; Kölsch, Uwe; Eisenblätter, Martin; Jahn, Heiko J.
In Deutschland wird die Legionärskrankheit in der Regel durch die Spezies Legionella (L.) pneumophila verursacht. Von rezidivierenden Fällen der Legionärskrankheit wird selten berichtet, sie sind entweder auf eine zweite ...
2017-06-01Zeitschriftenartikel
Clostridium difficile – ein unterschätztes Problem 
Arvand, Mardjan; Mielke, Martin
2018-12-13Zeitschriftenartikel
Wissenschaftliche Begründung zur Empfehlung einer Impfung mit dem Herpes zoster-subunit-Totimpfstoff 
Ständige Impfkommission (STIKO)
Die STIKO empfiehlt die Impfung mit einem adjuvantierten Herpes zoster-Subunit-(HZ/su-) Totimpfstoff zur Verhinderung von Herpes zoster (HZ) und Postherpetischer Neuralgie (PHN) allen Personen ab einem Alter von 60 Jahren ...
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