2019-04-14Zeitschriftenartikel
HIF1A and NFAT5 coordinate Na+-boosted antibacterial defense via enhanced autophagy and autolysosomal targeting
Neubert, Patrick; Weichselbaum, Andrea; Reitinger, Carmen; Schatz, Valentin; Schröder, Agnes; Ferdinand, John R.; Simon, Michaela; Bär, Anna-Lorena; Brochhausen, Christoph; Gerlach, Roman G.; Tomiuk, Stefan; Hammer, Karin; Wagner, Stefan; van Zandbergen, Ger; Binger, Katrina J.; Müller, Dominik N.; Kitada, Kento; Clatworthy, Menna R.; Kurts, Christian; Titze, Jens; Abdullah, Zeinab; Jantsch, Jonathan
Infection and inflammation are able to induce diet-independent Na+-accumulation without commensurate water retention in afflicted tissues, which favors the pro-inflammatory activation of mouse macrophages and augments their ...
