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2021-02-09Zeitschriftenartikel

Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection

Cingöz, Oya; Arnow, Nicolas D.; Torrents, Mireia Puig; Bannert, Norbert

Background The genomes of HIV-2 and some SIV strains contain the accessory gene vpx, which carries out several functions during infection, including the downregulation of SAMHD1. Vpx is also commonly used in experiments ...

2021-01-22Zeitschriftenartikel

Consistency of Social Interactions in Sooty Mangabeys and Chimpanzees

Mielke, Alexander; Preis, Anna; Samuni, Liran; Gogarten, Jan F.; Lester, Jack D.; Crockford, Catherine; Wittig, Roman M.

Predictability of social interactions can be an important measure for the social complexity of an animal group. Predictability is partially dependent on how consistent interaction patterns are over time: does the behavior ...

2021-02-25Zeitschriftenartikel

Wie steht es um die Frauengesundheit? Neuer Bericht der Gesundheitsberichterstattung am RKI ist erschienen

Saß, Anke-Christine; Krause, Laura; Hintzpeter, Birte; Prütz, Franziska

Am 9.12.2020 wurde der neue Frauengesundheits¬bericht des Robert Koch-Instituts (RKI) mit einer gemeinsamen Pressemitteilung vom Bundesminis¬terium für Gesundheit (BMG) und RKI publiziert. Der 400-seitige Bericht entstand ...

2021-01-22Zeitschriftenartikel

Everything counts - a method to determine viral suppression among people living with HIV using longitudinal data for the HIV care continuum - results of two large, German, multi-center real-life cohort studies over 20 years (1999–2018)

Schmidt, Daniel; Kollan, Christian; Stoll, Matthias; Hamouda, Osamah; Bremer, Viviane; Kurth, Tobias; Bartmeyer, Barbara

Background The aim of this study was to develop a standardized method to reconstruct persons’ individual viral load (VL) courses to determine viral suppression and duration of viremia for the HIV care continuum in Germany ...

2021-01-25Zeitschriftenartikel

Challenges to the Fight against Rabies—The Landscape of Policy and Prevention Strategies in Africa

Haekyung Haselbeck, Andrea; Rietmann, Sylvie; Tadesse, Birkneh Tilahun; Kling, Kerstin; Kaschubat-Dieudonné, Maria Elena; Marks, Florian; Wetzker, Wibke; Thöne-Reineke, Christa

Nearly 59,000 human deaths worldwide are attributable to rabies annually, of which more than a third occur in Africa. In recent years, progress has been made in both action and collaboration including implementation of ...

2021-02-16Zeitschriftenartikel

Acinetobacter stercoris sp. nov. isolated from output source of a mesophilic german biogas plant with anaerobic operating conditions

Pulami, Dipen; Schauss, Thorsten; Eisenberg, Tobias; Blom, Jochen; Schwengers, Oliver; Bender, Jennifer K; Wilharm, Gottfried; Kämpfer, Peter; Glaeser, Stefanie P.

The Gram-stain-negative, oxidase negative, catalase positive strain KPC-SM-21T, isolated from a digestate of a storage tank of a mesophilic German biogas plant, was investigated by a polyphasic taxonomic approach. Phylogenetic ...

2021-03-05Zeitschriftenartikel

COVID-19-Krankheitslast in Deutschland im Jahr 2020

Durch Tod und Krankheit verlorene Lebensjahre im Verlauf der Pandemie

Rommel, Alexander; von der Lippe, Elena; Plaß, Dietrich; Ziese, Thomas; Diercke, Michaela; an der Heiden, Matthias; Haller, Sebastian; Wengler, Annelene

Hintergrund: Die SARS-CoV-2-Pandemie hat im Jahr 2020 das Gesundheitswesen vor große Herausforderungen gestellt. Die COVID-19-Krankheitslast lässt sich durch den Verlust an Lebensjahren durch Krankheit oder Tod ausdrücken. ...

2020-12-18Zeitschriftenartikel

Correlation of mesolevel characteristics of the healthcare system and socioeconomic inequality in healthcare use: a scoping review protocol

Novelli, Anna; Schüttig, Wiebke; Spallek, Jacob; Wachtler, Benjamin; Diehl, Katharina; Moor, Irene; Richter, Matthias; Dragano, Nico; Sundmacher, Leonie

Introduction Although the impact of macrolevel characteristics of health systems on socioeconomic inequity in health has been studied extensively, the impact of access characteristics on a smaller scale of health systems ...

2021-02-03Zeitschriftenartikel

A Sarcina bacterium linked to lethal disease in sanctuary chimpanzees in Sierra Leone

Owens, Leah A.; Colitti, Barbara; Hirji, Ismail; Pizarro, Andrea; Jaffe, Jenny E.; Moittié, Sophie; Bishop-Lilly, Kimberly A.; Estrella, Luis A.; Voegtly, Logan J.; Kuhn, Jens H.; Suen, Garret; Deblois, Courtney L.; Dunn, Christopher D.; Juan-Sallés, Carles; Goldberg, Tony L.

Human and animal infections with bacteria of the genus Sarcina (family Clostridiaceae) are associated with gastric dilation and emphysematous gastritis. However, the potential roles of sarcinae as commensals or pathogens ...

2021-02-02Zeitschriftenartikel

Exploring how Syrian women manage their health after migration to Germany: results of a qualitative study

Kikhia, Salma; Gharib, Ghaith; Sauter, Alexandra; Caldeira Loss Vincens, Natalia; Loss, Julika

Background In the recent years, the number of Syrians living in Germany increased drastically due to the massive displacement caused by the Syrian conflict. Syrian migrant women in Germany are challenged by both the ...

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