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2022-01-20Zeitschriftenartikel
Meldedaten und KiTa-Register ergänzen sich in der Bewertung der Dynamik der SARS-CoV-2-Ausbrüche in Kindertageseinrichtungen 
Lehfeld, Ann-Sophie; Buchholz, Udo; Grgic, Mariana; Neuberger, Franz; Kruger, Susanne; Diercke, Michaela; Rexroth, Ute; Hamouda, Osamah; Haas, Walter
Daten zu SARS-CoV-2-bedingten Ausbrüchen in Kitas können wichtige Hinweise zur Einschätzung des Infektionsgeschehens im Kita-Setting liefern und sind ein wichtiger Bestandteil in der Gesamtbewertung des Pandemiegeschehens. ...
2022-01-20Zeitschriftenartikel
Lepra 2022 – Vereint für die Würde von Leprabetroffenen eintreten 
Kreibich, Saskia; Fastenau, Anil; Kasang, Christa
Der diesjährige internationale Weltlepratag steht unter dem Motto „United for Dignity“ und ruft dazu auf, gemeinsam die Würde Leprabetroffener, von denen viele nach wie vor unter krankheitsbedingter Stigmatisierung und ...
2022-01-06Zeitschriftenartikel
Monitoring und Evaluation des SARS-CoV-2-Infektionsgeschehens unter Schülerinnen und Schülern an Hamburgs Schulen 
Brändle, Tobias
Die Rolle von Schulen hinsichtlich des allgemeinen Pandemiegeschehens ist strittig. Um zur Beantwortung der Frage beizutragen, ob Schulen Ausgangspunkte für Infektionsherde darstellen, wurden Daten der Hamburger Behörde ...
2021-11-15Zeitschriftenartikel
Fusaricidins, Polymyxins and Volatiles Produced by Paenibacillus polymyxa Strains DSM 32871 and M1 
Mülner, Pascal; Schwarz, Elisa; Dietel, Kristin; Herfort, Stefanie; Jähne, Jennifer; Lasch, Peter; Cernava, Tomislav; Berg, Gabriele; Vater, Joachim
Paenibacilli are efficient producers of potent agents against bacterial and fungal pathogens, which are of great interest both for therapeutic applications in medicine as well as in agrobiotechnology. Lipopeptides produced ...
2021-05-25Zeitschriftenartikel
Nipah Virus Efficiently Replicates in Human Smooth Muscle Cells without Cytopathic Effect 
DeBuysscher, Blair L.; Scott, Dana P.; Rosenke, Rebecca; Wahl, Victoria; Feldmann, Heinz; Prescott, Joseph
Nipah virus (NiV) is a highly pathogenic zoonotic virus with a broad species tropism, originating in pteropid bats. Human outbreaks of NiV disease occur almost annually, often with high case-fatality rates. The specific ...
2020-09-08Zeitschriftenartikel
Silence as a way of niche adaptation: mecC-MRSA with variations in the accessory gene regulator (agr) functionality express kaleidoscopic phenotypes 
Huber, Charlotte; Stamm, Ivonne; Ziebuhr, Wilma; Marincola, Gabriella; Bischoff, Markus; Strommenger, Birgit; Jaschkowitz, Greta; Marciniak, Tessa; Cuny, Christiane; Witte, Wolfgang; Doellinger, Joerg; Schaudinn, Christoph; Thürmer, Andrea; Epping, Lennard; Semmler, Torsten; Lübke-Becker, Antina; Wieler, Lothar H.; Walther, Birgit
Functionality of the accessory gene regulator (agr) quorum sensing system is an important factor promoting either acute or chronic infections by the notorious opportunistic human and veterinary pathogen Staphylococcus ...
2020-11-12Zeitschriftenartikel
Simplified Bioprinting-Based 3D Cell Culture Infection Models for Virus Detection 
Koban, Robert; Lam, Tobias; Schwarz, Franziska; Kloke, Lutz; Bürge, Silvio; Ellerbrok, Heinz; Neumann, Markus
Studies of virus–host interactions in vitro may be hindered by biological characteristics of conventional monolayer cell cultures that differ from in vivo infection. Three-dimensional (3D) cell cultures show more in vivo-like ...
2021-02-01Zeitschriftenartikel
Interpretable detection of novel human viruses from genome sequencing data 
Bartoszewicz, Jakub M.; Seidel, Anja; Renard, Bernhard Y.
Viruses evolve extremely quickly, so reliable meth- ods for viral host prediction are necessary to safe- guard biosecurity and biosafety alike. Novel human- infecting viruses are difficult to detect with stan- dard ...
2021-02-15Zeitschriftenartikel
Genome-Wide Association Studies for the Detection of Genetic Variants Associated With Daptomycin and Ceftaroline Resistance in Staphylococcus aureus 
Weber, Robert E.; Fuchs, Stephan; Layer, Franziska; Sommer, Anna; Bender, Jennifer K.; Thürmer, Andrea; Werner, Guido; Strommenger, Birgit
Background: As next generation sequencing (NGS) technologies have experienced a rapid development over the last decade, the investigation of the bacterial genetic architecture reveals a high potential to dissect causal ...
2021-01-19Zeitschriftenartikel
Genome-Based Analyses of Fitness Effects and Compensatory Changes Associated with Acquisition of blaCMY-, blaCTX-M-, and blaOXA-48/VIM-1-Containing Plasmids in Escherichia coli 
Pietsch, Michael; Pfeifer, Yvonne; Fuchs, Stephan; Werner, Guido
Background: Resistance plasmids are under selective conditions beneficial for the bacterial host, but in the absence of selective pressure, this carriage may cause fitness costs. Compensation of this fitness burden is ...
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