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2016-10-20Zeitschriftenartikel
Identification and Characterization of VNI/VNII and Novel VNII/VNIV Hybrids and Impact of Hybridization on Virulence and Antifungal Susceptibility Within the C. neoformans/C. gattii Species Complex 
Aminnejad, Mojgan; Cogliati, Massimo; Duan, Shuyao; Arabatzis, Michael; Tintelnot, Kathrin; Castañeda, Elizabeth; Lazéra, Marcia; Velegraki, Aristea; Ellis, David; Sorrell, Tania C.; Meyer, Wieland
Cryptococcus neoformans and C. gattii are pathogenic basidiomycetous yeasts and the commonest cause of fungal infection of the central nervous system. Cryptococci are typically haploid but several inter-species, inter-varietal ...
2016-06-01Zeitschriftenartikel
APOBEC4 Enhances the Replication of HIV-1 
Marino, Daniela; Perković, Mario; Hain, Anika; Vasudevan, Ananda A. Jaguva; Hofmann, Henning; Hanschmann, Kay-Martin; Mühlebach, Michael D.; Schumann, Gerald G.; König, Renate; Cichutek, Klaus; Häussinger, Dieter; Münk, Carsten
APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, ...
2016-10-21Zeitschriftenartikel
Dictyostelium discoideum as a Novel Host System to Study the Interaction between Phagocytes and Yeasts 
Koller, Barbara; Schramm, Christin; Siebert, Susann; Triebel, János; Deland, Eric; Pfefferkorn, Anna M.; Rickerts, Volker; Thewes, Sascha
The social amoeba Dictyostelium discoideum is a well-established model organism to study the interaction between bacteria and phagocytes. In contrast, research using D. discoideum as a host model for fungi is rare. We ...
2016-11-28Zeitschriftenartikel
Detection of a cfr(B) Variant in German Enterococcus faecium Clinical Isolates and the Impact on Linezolid Resistance in Enterococcus spp. 
Bender, Jennifer K.; Fleige, Carola; Klare, Ingo; Fiedler, Stefan; Mischnik, Alexander; Mutters, Nico T.; Dingle, Kate E.; Werner, Guido
The National Reference Centre for Staphylococci and Enterococci in Germany has received an increasing number of clinical linezolid-resistant E. faecium isolates in recent years. Five isolates harbored a cfr(B) variant ...
2016-11-14Zeitschriftenartikel
Asymptomatic only at first sight: malaria infection among schoolchildren in highland Rwanda 
Sifft, Kevin C.; Geus, Dominik; Mukampunga, Caritas; Mugisha, Jean Claude; Habarugira, Felix; Fraundorfer, Kira; Bayingana, Claude; Ndoli, Jules; Umulisa, Irenee; Karema, Corine; Samson-Himmelstjerna, George von; Aebischer, Toni; Martus, Peter; Sendegeya, Augustin; Gahutu, Jean Bosco; Mockenhaupt, Frank P.
Background: Plasmodium infection and malaria in school children are increasingly recognized as a relevant public health problem, but data on actual prevalence and health consequences are insufficient. The present study ...
2016-11-28Zeitschriftenartikel
Online-Befragung von Klinikpersonal zur Influenza-Impfung (OKaPII-Studie) 
Robert Koch-Institut
2016-11-25Zeitschriftenartikel
Effectiveness, immunogenicity and safety of 23-valent pneumococcal polysaccharide vaccine revaccinations in the elderly: a systematic review 
Remschmidt, Cornelius; Harder, Thomas; Wichmann, Ole; Bogdan, Christian; Falkenhorst, Gerhard
Background: In many industrialized countries routine vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPSV-23) is recommended to prevent pneumococcal disease in the elderly. However, vaccine-induced ...
2016-11-23Zeitschriftenartikel
Metabolic Health in Relation to Body Size: Changes in Prevalence over Time between 1997-99 and 2008-11 in Germany 
Truthmann, Julia; Mensink, Gert; Bosy-Westphal, Anja; Scheidt-Nave, Christa; Schienkiewitz, Anja
Objective: The study examined potential changes in the proportion of metabolic health according to body size categories over time and across strata of sex and age, varying definitions of metabolic health. Methods: ...
2016-11-21Zeitschriftenartikel
Colistin-Resistenz bei Gram-negativen Bakterien – die Situation in Deutschland 
Robert Koch-Institut
2016-09-19Zeitschriftenartikel
Pericardial Tamponade in an Adult Suffering from Acute Mumps Infection 
Kahlfuss, Sascha; Flieger, Robert Rainer; Mankertz, Annette; Yilmaz, Kadir; Roepke, Torsten Kai
Here, we report a case of a 51-year-old man with acute pericardial tamponade requiring emergency pericardiocentesis after he suffered from sore throat, headache, malaise, and sweats for two weeks. Serological analyses ...
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