Browsing Artikel in Fachzeitschriften by Author "Quezada, Sergio A."
Now showing items 1-2 of 2
-
2024-10-02ZeitschriftenartikelMHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution Puttick, Clare; Jones, Thomas P.; Leung, Michelle M.; Galvez-Cancino, Felipe; Liu, Jiali; Varas-Godoy, Manuel; Rowan, Andrew; Pich, Oriol; Martinez-Ruiz, Carlos; Bentham, Robert; Dijkstra, Krijn K.; Black, James R. M.; Rosenthal, Rachel; Kanu, Nnennaya; Litchfield, Kevin; Salgado, Roberto; Moore, David A.; Van Loo, Peter; Jamal-Hanjani, Mariam; Quezada, Sergio A.; TRACERx Consortium; Swanton, Charles; McGranahan, NicholasDisruption of the class I human leukocyte antigen (HLA) molecules has important implications for immune evasion and tumor evolution. We developed major histocompatibility complex loss of heterozygosity (LOH), allele-specific ...
-
2024-05-31ZeitschriftenartikelRepresentation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models Hynds, Robert E.; Huebner, Ariana; Pearce, David R.; Hill, Mark S.; Akarca, Ayse U.; Moore, David A.; Ward, Sophia; Gowers, Kate H. C.; Karasaki, Takahiro; Al Bakir, Maise; Wilson, Gareth A.; Pich, Oriol; Martínez-Ruiz, Carlos; Md Mukarram Hossain, A. S.; Pearce, Simon P.; Sivakumar, Monica; Ben Aissa, Assma; Grönroos, Eva; Chandrasekharan, Deepak; Kolluri, Krishna K.; Towns, Rebecca; Wang, Kaiwen; Cook, Daniel E.; Bosshard-Carter, Leticia; Naceur-Lombardelli, Cristina; Rowan, Andrew J.; Verriah, Selvaraju; Litchfield, Kevin; Crosbie, Philip A. J.; Dive, Caroline; Quezada, Sergio A.; Janes, Sam M.; Jamal-Hanjani, Mariam; Marafioti, Teresa; TRACERx consortium; McGranahan, NicholasPatient-derived xenograft (PDX) models are widely used in cancer research. To investigate the genomic fidelity of non-small cell lung cancer PDX models, we established 48 PDX models from 22 patients enrolled in the TRACERx ...