Browsing Artikel in Fachzeitschriften by Title
Now showing items 3468-3487 of 3869
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2006-12-21ZeitschriftenartikelThe transmembrane envelope protein of HIV-1 and other retroviruses modulate cytokine production and induce Treg cells
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2013-08-07ZeitschriftenartikelThe Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression Numerous copies of endogenous retroviruses are present in the genome of mammals including man. Although most of them are defective, some, e.g., the human endogenous retroviruses HERV-K, were found to be expressed under ...
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2014-03-21ZeitschriftenartikelThe type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold Conjugative plasmid transfer presents a serious threat to human health as the most important means of spreading antibiotic resistance and virulence genes among bacteria. The required direct cell-cell contact is established ...
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2019-02-11ZeitschriftenartikelThe tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized ...
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2022-01-07ZeitschriftenartikelThe TZM-bl Reporter Cell Line Expresses Kynureninase That Can Neutralize 2F5-like Antibodies in the HIV-1 Neutralization Assay Induction of broadly neutralizing antibodies targeting ectodomain of the transmembrane (TM) glycoprotein gp41 HIV-1 provides a basis for the development of a universal anti-viral vaccine. The HeLa cell-derived TZM-bl ...
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2018-02-24ZeitschriftenartikelThe use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism High-throughput sequencing (HTS) has successfully identified novel resistance genes in enterococci and determined clonal relatedness in outbreak analysis. We report the use of HTS to investigate two concurrent outbreaks ...
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2018-08-06ZeitschriftenartikelThe usefulness of C-reactive protein in predicting malaria parasitemia in a sub-Saharan African region Background: Malaria remains a leading cause of childhood mortality in sub-Saharan Africa. Identifying patients who are at risk for severe manifestations at presentation still remains challenging. This study examines ...
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2020-02-22ZeitschriftenartikelThe Utility of Human Immune System Mice for High-Containment Viral Hemorrhagic Fever Research Human immune system (HIS) mice are a subset of humanized mice that are generated by xenoengraftment of human immune cells or tissues and/or their progenitors into immunodeficient mice. Viral hemorrhagic fevers (VHFs) cause ...
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2017-12-13ZeitschriftenartikelThe utilization of colonoscopy in Germany Colorectal cancer is one of the three most common cancers in German adults. There are several legally based examinations for the early detection of colorectal cancer. People aged 50 to 54 years can have a faecal blood ...
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2017-12-13ZeitschriftenartikelThe utilization of psychiatric and psychotherapeutic services in Germany – individual determinants and regional differences In Germany, the provision of health services to people with mental disorders is an issue that is subject to controversial debate. On the one hand, regional differences exist in the distribution of psychotherapists in ...
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2021-04-01ZeitschriftenartikelThe virome ofGerman bats: comparing virus discovery approaches Bats are known to be reservoirs of several highly pathogenic viruses. Hence, the interest in bat virus discovery has been increasing rapidly over the last decade. So far, most studies have focused on a single type of virus ...
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2021-06-14ZeitschriftenartikelThe whole is greater than the sum of its parts: profles of multiple mental health risk factors using Latent class analysis Background: The exposure to an accumulation of various risk factors during childhood and adolescence relative to a single risk is associated with poorer mental health. Identifcation of distinct constellations of risk ...
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2007-07-05ZeitschriftenartikelThe Yersinia enterocolitica type three secretion chaperone SycO is integrated into the Yop regulatory network and binds to the Yop secretion protein YscM1 Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these ...
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2018-02-23ZeitschriftenartikelThe zoonotic potential of Clostridium difficile from small companion animals and their owners Background: Clostridium difficile infections (CDI) in humans range from asymptomatic carriage to life-threatening intestinal disease. Findings on C. difficile in various animal species and an overlap in ribotypes (RTs) ...
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2021-09-19ZeitschriftenartikelTherapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available. ...
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2021ZeitschriftenartikelTherapie und Prophylaxe: Antikörper gegen COVID-19
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2023-05-15ZeitschriftenartikelTherapierelevante Antibiotikaresistenzen im One-Health-Kontext „One Health“ bezeichnet ein Konzept, das die Gesundheit von Menschen, Tieren und der Umwelt miteinander verbindet. In Deutschland gibt es umfangreiche Daten zur Antibiotikaresistenz (AMR) und multiresistenten Erregern (MRE) ...
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2007-12-03ZeitschriftenartikelTherapy-refractory Panton Valentine Leukocidin-positive community-acquired methicillin-sensitive Staphylococcus aureus sepsis with progressive metastatic soft tissue infection: a case report We report a case of fulminant multiple organ failure including the Acute Respiratory Distress Syndrome (ARDS), haemodynamic, and renal failure due to community-acquired methicillin-sensitive Panton Valentine Leukocidin ...
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2011-10-31ZeitschriftenartikelThermal stability of hepatitis E virus assessed by a molecular biological approach Background: Hepatitis E virus (HEV) is a pathogen of emerging concern in industrialized countries. The consumption of wild boar meat has been identified as one risk factor for autochthonous HEV infections. Only limited ...
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2021-10-25ZeitschriftenartikelThird generation cephalosporin resistance in clinical nontyphoidal Salmonella enterica in Germany and emergence of blaCTX-M-harbouring pESI plasmids Non-typhoidal Salmonella enterica is an important gastrointestinal pathogen causing a considerable burden of disease. Resistance to third generation cephalosporins poses a serious threat for treatment of severe infections. ...