Browsing Artikel in Fachzeitschriften by Title
Now showing items 4028-4047 of 4477
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2021-01-06ZeitschriftenartikelThe Status under EU Law of Organisms Developed through Novel Genomic Techniques In a ruling on 25 July 2018, the Court of Justice of the European Union concluded that organisms obtained by means of techniques/methods of mutagenesis constitute GMOs in the sense of Directive 2001/18, and that organisms ...
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2019-02-02ZeitschriftenartikelThe successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex ‘mix-and-match’ implementation package The emergence and spread of antimicrobial resistance is one of the major global issues currently threatening the health and wealth of nations, with effective guidelines and intervention strategies urgently required. Such ...
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2021-01-15ZeitschriftenartikelThe Superior Adherence Phenotype of E. coli O104:H4 is Directly Mediated by the Aggregative Adherence Fimbriae Type I Whereas the O104:H4 enterohemorrhagic Escherichia coli (EHEC) outbreak strain from 2011 expresses aggregative adherence fimbriae of subtype I (AAF/I), its close relative, the O104:H4 enteroaggregative Escherichia coli ...
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2023-01-17ZeitschriftenartikelThe Tol-Pal system of Acinetobacter baumannii is important for cell morphology, antibiotic resistance and virulence Acinetobacter baumannii is an opportunistic human pathogen that has become a global threat to healthcare institutions. This Gram-negative bacterium is one of the most successful human pathogens worldwide and responsible ...
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2006-12-21ZeitschriftenartikelThe transmembrane envelope protein of HIV-1 and other retroviruses modulate cytokine production and induce Treg cells
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2013-08-07ZeitschriftenartikelThe Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression Numerous copies of endogenous retroviruses are present in the genome of mammals including man. Although most of them are defective, some, e.g., the human endogenous retroviruses HERV-K, were found to be expressed under ...
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2014-03-21ZeitschriftenartikelThe type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold Conjugative plasmid transfer presents a serious threat to human health as the most important means of spreading antibiotic resistance and virulence genes among bacteria. The required direct cell-cell contact is established ...
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2023-10-26ZeitschriftenartikelThe type-2 Streptococcus canis M protein SCM-2 binds fibrinogen and facilitates antiphagocytic properties Streptococcus canis is a zoonotic agent that causes severe invasive diseases in domestic animals and humans, but little is known about its pathogenesis and virulence mechanisms so far. SCM, the M-like protein expressed by ...
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2019-02-11ZeitschriftenartikelThe tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family Apicomplexan parasites are auxotrophic for a range of amino acids which must be salvaged from their host cells, either through direct uptake or degradation of host proteins. Here, we describe a family of plasma membrane-localized ...
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2022-01-07ZeitschriftenartikelThe TZM-bl Reporter Cell Line Expresses Kynureninase That Can Neutralize 2F5-like Antibodies in the HIV-1 Neutralization Assay Induction of broadly neutralizing antibodies targeting ectodomain of the transmembrane (TM) glycoprotein gp41 HIV-1 provides a basis for the development of a universal anti-viral vaccine. The HeLa cell-derived TZM-bl ...
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2018-02-24ZeitschriftenartikelThe use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism High-throughput sequencing (HTS) has successfully identified novel resistance genes in enterococci and determined clonal relatedness in outbreak analysis. We report the use of HTS to investigate two concurrent outbreaks ...
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2018-08-06ZeitschriftenartikelThe usefulness of C-reactive protein in predicting malaria parasitemia in a sub-Saharan African region Background: Malaria remains a leading cause of childhood mortality in sub-Saharan Africa. Identifying patients who are at risk for severe manifestations at presentation still remains challenging. This study examines ...
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2020-02-22ZeitschriftenartikelThe Utility of Human Immune System Mice for High-Containment Viral Hemorrhagic Fever Research Human immune system (HIS) mice are a subset of humanized mice that are generated by xenoengraftment of human immune cells or tissues and/or their progenitors into immunodeficient mice. Viral hemorrhagic fevers (VHFs) cause ...
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2017-12-13ZeitschriftenartikelThe utilization of colonoscopy in Germany Colorectal cancer is one of the three most common cancers in German adults. There are several legally based examinations for the early detection of colorectal cancer. People aged 50 to 54 years can have a faecal blood ...
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2017-12-13ZeitschriftenartikelThe utilization of psychiatric and psychotherapeutic services in Germany – individual determinants and regional differences In Germany, the provision of health services to people with mental disorders is an issue that is subject to controversial debate. On the one hand, regional differences exist in the distribution of psychotherapists in ...
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2023-09-28ZeitschriftenartikelThe VBNC state: a fundamental survival strategy of Acinetobacter baumannii The viable but non-culturable (VBNC) state is a persistence strategy adopted by bacteria to withstand long-lasting periods of unfavorable conditions. VBNC cells evade classical detection methods and are therefore easily ...
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2021-04-01ZeitschriftenartikelThe virome ofGerman bats: comparing virus discovery approaches Bats are known to be reservoirs of several highly pathogenic viruses. Hence, the interest in bat virus discovery has been increasing rapidly over the last decade. So far, most studies have focused on a single type of virus ...
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2021-06-14ZeitschriftenartikelThe whole is greater than the sum of its parts: profles of multiple mental health risk factors using Latent class analysis Background: The exposure to an accumulation of various risk factors during childhood and adolescence relative to a single risk is associated with poorer mental health. Identifcation of distinct constellations of risk ...
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2007-07-05ZeitschriftenartikelThe Yersinia enterocolitica type three secretion chaperone SycO is integrated into the Yop regulatory network and binds to the Yop secretion protein YscM1 Background: Pathogenic yersiniae (Y. pestis, Y. pseudotuberculosis, Y. enterocolitica) share a virulence plasmid encoding a type three secretion system (T3SS). This T3SS comprises more than 40 constituents. Among these ...
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2018-02-23ZeitschriftenartikelThe zoonotic potential of Clostridium difficile from small companion animals and their owners Background: Clostridium difficile infections (CDI) in humans range from asymptomatic carriage to life-threatening intestinal disease. Findings on C. difficile in various animal species and an overlap in ribotypes (RTs) ...