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Now showing items 1841-1850 of 3394

2012-12-01Zeitschriftenartikel

HER2/neu DNA vaccination by intradermal gene delivery in a mouse tumor model

Gene gun is superior to jet injector in inducing CTL responses and protective immunity

Nguyen-Hoai, Tam; Kobelt, Dennis; Hohn, Oliver; Vu, Minh D.; Schlag, Peter M.; Dörken, Bernd; Norley, Stephen; Lipp, Martin; Walther, Wolfgang; Pezzutto, Antonio; Westermann, Jörg

DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal and dermal layers of ...

2013-08-07Zeitschriftenartikel

Synergistic Effects of Nonthermal Plasma and Disinfecting Agents against Dental Biofilms In Vitro

Koban, Ina; Geisel, Marie Henrike; Holtfreter, Birte; Jablonowski, Lukasz; Hübner, Nils-Olaf; Matthes, Rutger; Masur, Kai; Weltmann, Klaus-Dieter; Kramer, Axel; Kocher, Thomas

Aim. Dental biofilms play a major role in the pathogenesis of many dental diseases. In this study, we evaluated the synergistic effect of atmospheric pressure plasma and different agents in dentistry on the reduction of ...

2013-11-14Zeitschriftenartikel

Shiga Toxin-Producing Escherichia coli O157 Is More Likely to Lead to Hospitalization and Death than Non-O157 Serogroups – Except O104

Preußel, Karina; Höhle, Michael; Stark, Klaus; Werber, Dirk

The clinical spectrum following infection with Shiga toxin-producing Escherichia coli (STEC) is wide ranging and includes hemorrhagic colitis and life-threatening hemolytic uremic syndrome (HUS). Severity of STEC illness ...

2013-11-14Zeitschriftenartikel

Evidence for the transmission of Salmonella from reptiles to children in Germany, July 2010 to October 2011

Pees, Michael; Rabsch, Wolfgang; Plenz, B.; Fruth, Angelika; Prager, Rita; Simon, Sandra; Schmidt, V.; Münch, Sebastian; Braun, Peggy

This study examines the Salmonella status in reptiles kept in households with children suffering from gastroenteritis due to an exotic Salmonella serovar, to obtain information on possible transmission paths. A number of ...

2012-11-21Zeitschriftenartikel

Carrier prevalence, secondary household transmission and long-term shedding in two districts during the Escherichia coli O104:H4 outbreak in Germany, 2011

Sin, Muna Abu; Takla, Anja; Flieger, Antje; Prager, Rita; Fruth, Angelika; Tietze, Erhard; Fink, Eckhart; Korte, Jutta; Schink, Susanne; Höhle, Michael; Eckmanns, Tim

Background: From May-July 2011, Germany experienced a large Shiga toxin-producing E. coli (STEC) O104:H4 outbreak. Our objective was to identify the prevalence of STEC O104:H4 carriers in households in highly affected ...

2013-10-21Zeitschriftenartikel

Evaluation of Non-Invasive Biological Samples to Monitor Staphylococcus aureus Colonization in Great Apes and Lemurs

Schaumburg, Frieder; Mugisha, Lawrence; Kappeller, Peter; Fichtel, Claudia; Köck, Robin; Köndgen, Sophie; Becker, Karsten; Boesch, Christophe; Peters, Georg; Leendertz, Fabian

Introduction: Reintroduction of endangered animals as part of conservational programs bears the risk of importing human pathogens from the sanctuary to the natural habitat. One bacterial pathogen that serves as a model ...

2013-09-04Zeitschriftenartikel

Skin Lesions in European Hibernating Bats Associated with Geomyces destructans, the Etiologic Agent of White-Nose Syndrome

Wibbelt, Gudrun; Puechmaille, Sébastien J.; Ohlendorf, Bernd; Mühldorfer, Kristin; Bosch, Thijs; Görföl, Tamás; Passior, Karsten; Kurth, Andreas; Lacremans, Daniel; Forget, Frédéric

White-nose syndrome (WNS) has claimed the lives of millions of hibernating insectivorous bats in North America. Its etiologic agent, the psychrophilic fungus Geomyces destructans, causes skin lesions that are the hallmark ...

2013-09-10Zeitschriftenartikel

Age biases in a large HIV and sexual behaviour-related internet survey among MSM

Marcus, Ulrich; Hickson, Ford; Weatherburn, Peter; Schmidt, Axel J.

Background: Behavioural data from MSM are usually collected in non-representative convenience samples, increasingly on the internet. Epidemiological data from such samples might be useful for comparisons between countries, ...

2013-09-11Zeitschriftenartikel

Risk Factors Associated with the Community-Acquired Colonization of Extended-Spectrum Beta-Lactamase (ESBL) Positive Escherichia Coli. An Exploratory Case-Control Study

Leistner, Rasmus; Meyer, Elisabeth; Gastmeier, Petra; Pfeifer, Yvonne; Eller, Christoph; Dem, Petra; Schwab, Frank

Background: The number of extended-spectrum beta-lactamase (ESBL) positive (+) Escherichia coli is increasing worldwide. In contrast with many other multidrug-resistant bacteria, it is suspected that they predominantly ...

2013-04-29Zeitschriftenartikel

One-day point prevalence of emerging bacterial pathogens in a nationwide sample of 62 German hospitals in 2012 and comparison with the results of the one-day point prevalence of 2010

Wegner, Christian; Hübner, Nils-Olaf; Gleich, Sabine; Thalmaier, Ulrike; Krüger, Colin M.; Kramer, Axel

Hintergrund: Die Resistenzentwicklung gegen Antibiotika ist eine weltweit bedrohliche Situation. Zur Bekämpfung von multiresistenten Erregern (MRE) wurden in allen deutschen Bundesländern infektiologische Netzwerke der ...

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