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2015-11-26Zeitschriftenartikel
Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples 
Simon, Stéphanie; Fiebig, Uwe; Liu, Yvonne; Tierney, Rob; Dano, Julie; Worbs, Sylvia; Endermann, Tanja; Nevers, Marie-Claire; Volland, Hervé; Sesardic, Dorothea; Dorner, Martin
Botulinum neurotoxins (BoNTs) cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A–G), of which serotypes A, B, E, and F cause the disease in humans. ...
2015-11-26Zeitschriftenartikel
Generation and Characterization of Six Recombinant Botulinum Neurotoxins as Reference Material to Serve in an International Proficiency Test 
Weisemann, Jasmin; Krez, Nadja; Fiebig, Uwe; Worbs, Sylvia; Skiba, Martin; Endermann, Tanja; Dorner, Martin; Bergström, Tomas; Muñoz, Amalia; Zegers, Ingrid; Müller, Christian; Jenkinson, Stephen P.; Avondet, Marc-Andre; Delbrassinne, Laurence; Denayer, Sarah; Zeleny, Reinhard; Schimmel, Heinz; Åstot, Crister; Dorner, Brigitte; Rummel, Andreas
The detection and identification of botulinum neurotoxins (BoNT) is complex due to the existence of seven serotypes, derived mosaic toxins and more than 40 subtypes. Expert laboratories currently use different technical ...
2015-10-26Zeitschriftenartikel
Recommended Immunological Assays to Screen for Ricin-Containing Samples 
Simon, Stéphanie; Worbs, Sylvia; Avondet, Marc-André; Tracz, Dobryan M.; Dano, Julie; Schmidt, Lisa; Volland, Hervé; Dorner, Brigitte; Corbett, Cindi R.
Ricin, a toxin from the plant Ricinus communis, is one of the most toxic biological agents known. Due to its availability, toxicity, ease of production and absence of curative treatments, ricin has been classified by the ...
2015-11-24Zeitschriftenartikel
Random sampling of the Central European bat fauna reveals the existence of numerous hitherto unknown adenoviruses 
Vidovszky, Márton Z.; Kohl, Claudia; Boldogh, Sándor; Görföl, Tamás; Wibbelt, Gudrun; Kurth, Andreas; Harrach, Balázs
From over 1250 extant species of the order Chiroptera, 25 and 28 are known to occur in Germany and Hungary, respectively. Close to 350 samples originating from 28 bat species (17 from Germany, 27 from Hungary) were screened ...
2014-04-01Zeitschriftenartikel
Disagreement of the two oscillometric blood pressure measurement devices, Datascope Accutorr Plus and Omron HEM-705CP II, and bidirectional conversion of blood pressure values. 
Adler, Carolin; Ellert, Ute; Neuhauser, Hannelore
Objective(s): Oscillometric blood pressure (BP) measurement devices frequently replace the standard mercury sphygmomanometer. Comparisons of oscillometric devices are rare, but their agreement is important to ensure ...
2009-01-21Zeitschriftenartikel
Correlations Between Allergic and Infectious Diseases – Results of the Latest German National Health Survey (NHS98) and the German Health Interview and Examination Survey for Children and Adolescents (KiGGS) 
Langen, Ute; Röhme, J.
In the literature, according to the hygiene hypothesis, infections should be expected to correlate with fewer allergies. However, several studies clearly show that infections – especially infections of the upper respiratory ...
2015-11-26Zeitschriftenartikel
Preface Biological Toxins—Ancient Molecules Posing a Current Threat 
Dorner, Brigitte; Rummel, Andreas
2014-03-06Zeitschriftenartikel
Tuberculosis control in big cities and urban risk groups in the European Union: a consensus statement 
Hest, N. A. van; Aldridge, R. W.; Vries, G. de; Sandgren, A.; Hauer, Barbara; Hayward, A.; Oñate, W. Arrazola de; Haas, Walter; Codecasa, L. R.; Caylà, J. A.; Story, A.; Antoine, D.; Gori, A.; Quabeck, Levke; Jonsson, J.; Wanlin, M.; Orcau, À.; Rodes, A.; Dedicoat, M.; Antoun, F.; Deutekom, H. van; Keizer, S. T.; Abubakar, I.
In low-incidence countries in the European Union (EU), tuberculosis (TB) is concentrated in big cities, especially among certain urban high-risk groups including immigrants from TB high-incidence countries, homeless people, ...
2014-02-14Zeitschriftenartikel
SecA is required for membrane targeting of the cell division protein DivIVA in vivo 
Halbedel, Sven; Kawai, Maki; Breitling, Reinhard; Hamoen, Leendert W.
The conserved protein DivIVA is involved in different morphogenetic processes in Gram-positive bacteria. In Bacillus subtilis, the protein localizes to the cell division site and cell poles, and functions as a scaffold for ...
2014-03-20Zeitschriftenartikel
Laboratory diagnosis of paediatric tuberculosis in the European Union/European Economic Area: analysis of routine laboratory data, 2007 to 2011 
Sanchini, Andrea; Fiebig, L; Drobniewski, F.; Haas, Walter; Richter, Elvira; Katalinic-Jankovic, V.; Pimkina, E.; Skenders, G.; Cirillo, D. M.; Balabanova, Yanina
Laboratory confirmation of paediatric tuberculosis (TB) is frequently lacking. We reviewed the range of routine laboratory tests and their performance in different biological samples used to diagnose active TB in children. ...
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