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2010-10-21Zeitschriftenartikel
High-throughput microarray technology in diagnostics of enterobacteria based on genome-wide probe selection and regression analysis 
Friedrich, Torben; Rahmann, Sven; Weigel, Wilfried; Rabsch, Wolfgang; Fruth, Angelika; Ron, Eliora; Gunzer, Florian; Dandekar, Thomas; Hacker, Jörg; Müller, Tobias; Dobrindt, Ulrich
Background: The Enterobacteriaceae comprise a large number of clinically relevant species with several individual subspecies. Overlapping virulence-associated gene pools and the high overall genome plasticity often ...
2010-05-17Zeitschriftenartikel
Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells 
Bachem, Annabell; Güttler, Steffen; Hartung, Evelyn; Ebstein, Frédéric; Schaefer, Michael; Tannert, Astrid; Salama, Abdulgabar; Movassaghi, Kamran; Opitz, Corinna; Mages, Hans Werner; Henn, Volker; Kloetzel, Peter-Michael; Gurka, Stephanie; Kroczek, Richard
In recent years, human dendritic cells (DCs) could be subdivided into CD304+ plasmacytoid DCs (pDCs) and conventional DCs (cDCs), the latter encompassing the CD1c+, CD16+, and CD141+ DC subsets. To date, the low frequency ...
2008-02-29Zeitschriftenartikel
A comparison of the active surveillance of scrapie in the European Union 
Vilas, Victor Javier Del Rio; Böhning, Dankmar; Kuhnert, Ronny
The abattoir and the fallen stock surveys constitute the active surveillance component aimed at improving the detection of scrapie across the European Union. Previous studies have suggested the occurrence of significant ...
2009-08-06Zeitschriftenartikel
Transcription of the phage-encoded Panton–Valentine leukocidin of Staphylococcus aureus is dependent on the phage life-cycle and on the host background 
Wirtz, Christiane; Witte, Wolfgang; Wolz, Christiane; Goerke, Christiane
Panton-Valentine leukocidin (PVL) is a pore-forming, bi-component toxin secreted by Staphylococcus aureus strains epidemiologically associated with diseases such as necrotizing pneumonia and skin and soft-tissue infections. ...
2009-10-15Zeitschriftenartikel
Vertigo: Epidemiologic Aspects 
Neuhauser, Hannelore; Lempert, Thomas
Vertigo is a frequent symptom in the general population with a 12-month prevalence of 5% and an incidence of 1.4% in adults. Its prevalence rises with age and is about two to three times higher in women than in men. The ...
2009-08-06Zeitschriftenartikel
Food intake of young people with a migration background living in Germany 
Kleiser, Christina; Mensink, Gert; Neuhauser, Hannelore; Schenk, Liane; Kurth, Bärbel-Maria
Objective: To explore the food intake of young migrants living in Germany. Design: Children and adolescents aged 0 to 17 years living in Germany, including 17?1% with a migration background, were examined in a representative ...
2010-10-24Zeitschriftenartikel
Infektionsepidemiologische Daten von Blutspendern in Deutschland 2007 
Offergeld, Ruth; Ritter, Sabine; Quabeck, Levke; Hamouda, Osamah
Gemäß § 22 Transfusionsgesetz (TFG) melden alle Blut- und Plasmaspendeeinrichtungen in Deutschland ihre infektionsepidemiologischen Daten an das Robert Koch-Institut (RKI). Diese erlauben Aussagen über die Infektionshäufigkeit ...
2010-08-11Zeitschriftenartikel
Mumps virus small hydrophobic protein targets ataxin-1 ubiquitin-like interacting protein (ubiquilin 4) 
Woznik, Maria; Rödner, Claudia; Lemon, Ken; Rima, Bert; Mankertz, Annette; Finsterbusch, Tim
The small hydrophobic (SH) protein of mumps virus has been reported to interfere with innate immunity by inhibiting tumour necrosis factor alpha-mediated apoptosis. In a yeast two-hybrid screen we have identified the ...
2010-11-11Zeitschriftenartikel
Reduced Treg frequency in LFA-1-deficient mice allows enhanced T effector differentiation and pathology in EAE 
Gültner, Sandra; Kuhlmann, Tanja; Hesse, Amke; Weber, Jan P.; Riemer, Constanze; Baier, Michael; Hutloff, Andreas
The αLβ2-integrin LFA-1 (CD11a/CD18) is known as an important molecule for leukocyte migration. However, the precise role of LFA-1 in the pathogenesis of EAE has so far remained unclear. We describe here the disease ...
2010-06-22Zeitschriftenartikel
Aktueller Stand zur Raumdekontamination mit gasförmigem Wasserstoffperoxid 
Reichenbacher, Detlef; Thanheiser, Marc; Krüger, Dominique
Labore, Labortechnik und Versuchstierhaltung in den Sicherheitsbereichen S3 und S4 müssen gemäß Gentechnikgesetz speziellen Anforderungen an die Dekontamination von komplexen Oberflächen in Räumen, Schleusen und ...
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