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2015-11-03Zeitschriftenartikel
In vitro activity of ceftobiprole against key pathogens associated with pneumonia in hospitalized patients: results from the PEG surveillance study, 2010 
Kresken, Michael; Körber-Irrgang, Barbara; Kaase, Martin; Layer, Franziska; Pfeifer, Yvonne; Werner, Guido; Hafner, Dieter
Empirical treatment of hospital-acquired pneumonia (HAP) has increasingly been threatened by methicillin-resistant Staphylococcus aureus (MRSA) and multidrug resistant Gram-negative pathogens. In contrast, empirical treatment ...
2015-12-17Zeitschriftenartikel
Ongoing outbreak of invasive listeriosis, Germany, 2012 to 2015 
Ruppitsch, W.; Prager, Rita; Halbedel, Sven; Hyden, P.; Pietzka, A.; Huhulescu, S.; Lohr, D.; Schönberger, K.; Aichinger, Elisabeth; Hauri, Anja M.; Stark, Klaus; Vygen, Sabine; Tietze, Erhard; Allerberger, Franz; Wilking, Hendrik
Listeriosis patient isolates in Germany have shown a new identical pulsed-field gel electrophoresis (PFGE) pattern since 2012 (n = 66). Almost all isolates (Listeria monocytogenes serotype 1/2a) belonged to cases living ...
2015-09-24Zeitschriftenartikel
First Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis 
Detering, H.; Aebischer, Toni; Dabrowski, Piotr Wojtek; Radonić, Aleksandar; Nitsche, Andreas; Renard, Bernhard Y.; Kiderlen, Albrecht
The free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 ...
2015-11-19Zeitschriftenartikel
Complete Genome Sequence of the Gut Commensal and Laboratory Strain Enterococcus faecium 64/3 
Bender, Jennifer K.; Fiedler, Stefan; Klare, Ingo; Werner, Guido
The genome sequence of the commensal and widely used laboratory strain Enterococcus faecium 64/3 was resolved by means of PacificBioscience and Illumina whole-genome sequencing. The genome comprises 2,575,333 bp with 2,382 ...
2015-07-11Zeitschriftenartikel
Vitamin D status among adults in Germany – results from the German Health Interview and Examination Survey for Adults (DEGS1) 
Rabenberg, Martina; Scheidt-Nave, Christa; Busch, Markus A.; Rieckmann, Nina; Hintzpeter, Birte; Mensink, Gert
Background: In 1998, more than half of the adult population in Germany had serum 25-hydroxy-vitamin-D [25(OH)D] levels below the common threshold of 50 nmol/l. Since then, there has been a lot of attention for vitamin D ...
2015-06-16Zeitschriftenartikel
Cross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa 
Bielecki, Piotr; Jensen, Vanessa; Schulze, Wiebke; Gödeke, Julia; Strehmel, Janine; Eckweiler, Denitsa; Nicolai, Tanja; Bielecka, Agata; Wille, Thorsten; Gerlach, Roman; Häussler, Susanne
Two-component systems (TCS) serve as stimulus-response coupling mechanisms to allow organisms to adapt to a variety of environmental conditions. The opportunistic pathogen Pseudomonas aeruginosa encodes for more than 100 ...
2015-06-08Zeitschriftenartikel
Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial 
Brückner, Sina; Agnandji, Selidji T.; Berberich, Stefan; Bache, Emmanuel; Fernandes, José F.; Schweiger, Brunhilde; Loembe, Marguerite Massinga; Engleitner, Thomas; Lell, Bertrand; Mordmüller, Benjamin; Adegnika, Ayola A.; Yazdanbakhsh, Maria; Kremsner, Peter G.; Esen, Meral
Background: Helminth infections are a major public health problem, especially in the tropics. Infected individuals have an altered immune response with evidence that antibody response to vaccination is impaired. Hence, ...
2015-06-11Zeitschriftenartikel
Three Dimensional Checkerboard Synergy Analysis of Colistin, Meropenem, Tigecycline against Multidrug-Resistant Clinical Klebsiella pneumonia Isolates 
Stein, Claudia; Makarewic, Oliwia; Bohnert, Jürgen A.; Pfeifer, Yvonne; Kesselmeier, Miriam; Hagel, Stefan; Pletz, Mathias W.
The spread of carbapenem-non-susceptible Klebsiella pneumoniae strains bearing different resistance determinants is a rising problem worldwide. Especially infections with KPC (Klebsiella pneumoniae carbapenemase) - producers ...
2014-07-29Zeitschriftenartikel
Wohnumfeld – Stolperstein oder Weg zum gesunden Altern? 
Strobl, Ralf; Maier, Werner; Mielck, Andreas; Fuchs, Judith; Richter-Kornweitz, A.; Gostomzyk, J.; Grill, Eva
Neben einer guten medizinischen Versorgung ist die Struktur des Wohnumfeldes von zentraler Bedeutung, um soziale Teilhabe älterer Menschen zu fördern. Für die Kommunen bedeutet dies, dass sie der altersgerechten Gestaltung ...
2015-07-25Zeitschriftenartikel
Change in the association of body mass index and systolic blood pressure in Germany – national cross-sectional surveys 1998 and 2008–2011 
Adler, Carolin; Rosario, Angelika Schaffrath; Diederichs, Claudia; Neuhauser, Hannelore
Background: A recent weakening and even decoupling of the association of body mass index (BMI) and systolic blood pressure (SBP) in population data was reported, i. a. for Western Europe. Methods: The association ...
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