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2011-09-25Zeitschriftenartikel

Overview of Biologic Response Modifiers in Infectious Disease

Masihi, K. Noel; Schäfer, Hubert

The conventional treatment of infectious agents is increasingly encountering antimicrobial resistance. This resistance has led to an intense search for novel treatment modalities for infectious diseases. Elucidation of the ...

2012-10-02Zeitschriftenartikel

Scope and Impact of International Research in Human Pluripotent Stem Cells

Löser, Peter; Kobold, Sabine; Guhr, Anke; Müller, Franz-Josef; Kurtz, Andreas

In a recent study published in this journal it was claimed that the rate of publications from US-based authors in the human embryonic stem cell (hESC) research field was slowing or even declining from 2008 to 2010. It was ...

2008-11-05Zeitschriftenartikel

Analysis of influenza B virus NS1 protein trafficking reveals a novel interaction with nuclear speckle domains

Schneider, Jana; Dauber, Bianca; Melén, Krister; Julkunen, Ilkka; Wolff, Thorsten

Many proteins that function in the transcription, maturation, and export of metazoan mRNAs are concentrated in nuclear speckle domains, indicating that the compartment is important for gene expression. Here, we show that ...

2011-10-22Zeitschriftenartikel

Vibrio-Infektionen durch Lebensmittel und Meerwasser

Das Netzwerk „VibrioNet“ stellt sich vor

Alter, T.; Appel, Bernd; Bartelt, E.; Dieckmann, Ralf; Eichhorn, C.; Erler, R.; Frank, Christina; Gerdts, G.; Gunzer, Florian; Hühn, S.; Neifer, Janina; Oberheitmann, B.; Strauch, Eckhard

Vibrionen sind salzliebende Bakterien, die in Oberflächen- und Küstengewässern sowie Meerestieren weltweit verbreitet sind. In vielen Ländern stellen pathogene Vibrio-Spezies eine der Hauptursachen von bakteriell verursachten ...

2011-10-19Zeitschriftenartikel

Growth of influenza A virus is not impeded by simultaneous removal of the cholesterol binding and acylation sites in the M2 protein

Thaa, Bastian; Tielesch, Claudia; Möller, Lars; Schmitt, Armin O.; Wolff, Thorsten; Bannert, Norbert; Herrmann, Andreas; Veit, Michael

Influenza virus assembly and budding occur in the 'budozone', a coalesced raft domain in the plasma membrane. The viral transmembrane protein M2 is implicated in virus particle scission, the ultimate step in virus budding, ...

2011-05-17Zeitschriftenartikel

Dietary patterns are associated with cardiometabolic risk factors in a representative study population of German adults

Heidemann, Christin; Scheidt-Nave, Christa; Richter, Almut; Mensink, Gert

Studies that investigated complex actual eating behaviours of the general population and their relation to cardiometabolic risk markers are sparse. We aimed to identify dietary patterns within a nationally representative ...

2011-10-07Zeitschriftenartikel

From types to trees: Reconstructing the spatial spread of Staphylococcus aureus based on DNA variation

Nübel, Ulrich; Strommenger, Birgit; Layer, Franziska; Witte, Wolfgang

Tracing the spatial spread of pathogens is a key objective of molecular infectious disease epidemiology. Accordingly, a wide range of genotyping approaches have been used to monitor the dissemination of Staphylococcus ...

2011-04-01Zeitschriftenartikel

Schlafstörungen und schlechte Schulleistungen bei Grundschulkindern

Wiechers, S.; Schlarb, A. A.; Urschitz, Michael S.; Eggebrecht, E.; Schlaud, Martin; Poets, Christian F.

Ziel: Schlafstörungen können die Tagesleistung beeinflussen. Daher wurde die Prävalenz von Schlafstörungen und ihr Zusammenhang mit schlechten Schulleistungen in einer Querschnittsstudie an 27 Grundschulen in Hannover ...

2010-05-01Zeitschriftenartikel

Differential expression of human endogenous retrovirus K transcripts in primary human melanocytes and melanoma cell lines after UV irradiation.

Reiche, Janine; Pauli, Georg; Ellerbrok, Heinz

Human endogenous retroviruses (HERVs) are discussed as causative agents of various diseases including cancers. Expression of endogenous retroviral sequences can be induced by ultraviolet (UV) light, which is also considered ...

2011-01-24Zeitschriftenartikel

Prevalence of Chlamydia trachomatis among young German adolescents, 2005–06

Desai, Sarika; Meyer, Thomas; Thamm, Michael; Hamouda, Osamah; Bremer, Viviane

Background: Chlamydia trachomatis prevalence among 12–17-year-old adolescents in Germany was determined in the present study. Methods: A random age-stratified sample of 1815 urine specimens of boys and girls was selected ...

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