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2018-05-15Zeitschriftenartikel
Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study 
Pauly, Maude; Black, Antony P.; Khampanisong, Phonepaseuth; Nouanthong, Phonethipsavanh; Hübschen, Judith M.; Nanthavong, Naphavanh; Sayasinh, Kong; Jutavijittum, Prapan; Samountry, Bounthome; Xeuatvongsa, Anonh; Diedrich, Sabine; Muller, Claude P.
In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts ...
2018-02-24Zeitschriftenartikel
The use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism 
Shaw, Timothy D.; Fairley, D. J.; Schneiders, T.; Pathiraja, M.; Hill, R. L. R.; Werner, Guido; Elborn, J. S.; McMullan, R.
High-throughput sequencing (HTS) has successfully identified novel resistance genes in enterococci and determined clonal relatedness in outbreak analysis. We report the use of HTS to investigate two concurrent outbreaks ...
2018-05-23Zeitschriftenartikel
HDV infection rates in northern Vietnam 
Binh, Mai Thanh; Hoan, Nghiem Xuan; Tong, Hoang Van; Giang, Dao Phuong; Sy, Bui Tien; Toan, Nguyen Linh; Song, Le Huu; Bang, Mai Hong; Wedemeyer, Heiner; Meyer, Christian G.; Kremsner, Peter G.; Bock, Thomas; Velavan, Thirumalaisamy P.
Hepatitis D caused by the hepatitis delta virus (HDV) is a serious health problem in many regions of the world. A total of 546 HBV-infected patients were enrolled from 2013 to 2015 and classified clinically into the subgroups ...
2018-01-24Zeitschriftenartikel
Comparative analysis of Salivette® and paraffin gum preparations for establishment of a metaproteomics analysis pipeline for stimulated human saliva 
Rabe, Alexander; Salazar, Manuela Gesell; Fuchs, Stephan; Kocher, Thomas; Völker, Uwe
The value of saliva as a diagnostic tool can be increased by taxonomic and functional analyses of the microbiota as recently demonstrated. In this proof-of-principle study, we compare two collection methods (Salivette® ...
2018-05-10Zeitschriftenartikel
Draft Genome Sequences of Plant-Associated Bacillus Strains Isolated from the Qinghai-Tibetan Plateau 
Wu, Huijun; Borriss, Rainer; Xue, Pengqi; Liu, Fang; Qiao, Junqing; Schneider, Andy; Lasch, Peter; Gao, Xuewen
Here, we report the draft genome sequences of 45 plant-associated Bacillus strains isolated from the Qinghai-Tibetan plateau. According to their genome sequences, 28 isolates were assigned to 10 Bacillus species. Seventeen ...
2018-07-16Zeitschriftenartikel
Increasing influenza and pneumococcal vaccine uptake in the elderly: study protocol for the multi-methods prospective intervention study Vaccination60+ 
Betsch, Cornelia; Rossmann, Constanze; Pletz, Mathias W.; Vollmar, Horst C.; Freytag, Antje; Wichmann, Ole; Hanke, Regina; Hanke, Wolfgang; Heinemeier, Dorothee; Schmid, Philipp; Eitze, Sarah; Weber, Winja; Reinhardt, Anne; Küpke, Nora K.; Forstner, Christina; Fleischmann-Struzek, Carolin; Mikolajetz, Anna; Römhild, Josephine; Neufeind, Julia; Rieck, Thorsten; Suchecka, Kasia; Reinhart, Konrad
Background: Influenza and pneumococcal vaccination can prevent disease and potentially life-threatening complications like sepsis. Elderly people have an increased risk of severe disease and therefore constitute a major ...
2018-05-18Zeitschriftenartikel
Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver 
Wymant, Chris; Blanquart, François; Golubchik, Tanya; Gall, Astrid; Bakker, Margreet; Bezemer, Daniela; Croucher, Nicholas J.; Hall, Matthew; Hillebregt, Mariska; Ong, Swee Hoe; Ratmann, Oliver; Albert, Jan; Bannert, Norbert; Fellay, Jacques; Fransen, Katrien; Gourlay, Annabelle; Grabowski, M. Kate; Gunsenheimer-Bartmeyer, Barbara; Günthard, Huldrych F.; Kivelä, Pia; Kouyos, Roger; Laeyendecker, Oliver; Liitsola, Kirsi; Meyer, Laurence; Porter, Kholoud; Ristola, Matti; van Sighem, Ard; Berkhout, Ben; Cornelissen, Marion; Kellam, Paul; Reiss, Peter; Fraser, Christophe
Studying the evolution of viruses and their molecular epidemiology relies on accurate viral sequence data, so that small differences between similar viruses can be meaningfully interpreted. Despite its higher throughput ...
2018-06-14Zeitschriftenartikel
Multispecies and Clonal Dissemination of OXA-48 Carbapenemase in Enterobacteriaceae From Companion Animals in Germany, 2009—2016 
Pulss, Sandra; Stolle, Inka; Stamm, Ivonne; Leidner, Ursula; Heydel, Carsten; Semmler, Torsten; Prenger-Berninghoff, Ellen; Ewers, Christa
The increasing spread of carbapenemase-producing Enterobacteriaceae (CPE) poses a serious threat to public health. Recent studies suggested animals as a putative source of such bacteria. We investigated 19,025 Escherichia ...
2018-06-12Zeitschriftenartikel
High genomic diversity of multi-drug resistant wastewater Escherichia coli 
Mahfouz, Norhan; Caucci, Serena; Achatz, Eric; Semmler, Torsten; Guenther, Sebastian; Berendonk, Thomas U.; Schroeder, Michael
Wastewater treatment plants play an important role in the emergence of antibiotic resistance. They provide a hot spot for exchange of resistance within and between species. Here, we analyse and quantify the genomic diversity ...
2018-06-22Zeitschriftenartikel
The Expression of Uncoupling Protein 3 Coincides With the Fatty Acid Oxidation Type of Metabolism in Adult Murine Heart 
Hilse, Karolina E.; Rupprecht, Anne; Egerbacher, Monika; Bardakji, Sarah; Zimmermann, Lars; Seiler Wulczyn, Andrea E. M.; Pohl, Elena E.
The involvement of mitochondrial uncoupling proteins 2 and 3 in the pathogenesis of cardiovascular diseases is widely acknowledged. However, contradictory reports show that the functions of UCP2/UCP3 are still disputed. ...
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