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2019-01-31Zeitschriftenartikel
Molecular Evolution of Human Adenovirus (HAdV) Species C 
Dhingra, Akshay; Hage, Elias; Ganzenmueller, Tina; Böttcher, Sindy; Hofmann, Jörg; Hamprecht, Klaus; Obermeier, Patrick; Rath, Barbara; Hausmann, Fabian; Dobner, Thomas; Heim, Albert
Currently, 88 different Human Adenovirus (HAdV) types are grouped into seven HAdV species A to G. Most types (57) belong to species HAdV-D. Recombination between capsid genes (hexon, penton and fiber) is the main factor ...
2019-01-28Zeitschriftenartikel
Serum vitamin D levels in Berliners of Turkish descent –a cross-sectional study 
Krist, Lilian; Keller, Theresa; Becher, Heiko; Jöckel, Karl-Heinz; Schlaud, Martin; Willich, Stefan N.; Keil, Thomas
Background Vitamin D levels may differ between migrant and non-migrant populations, especially among non-western immigrants living in a country with limited sun exposure such as Germany. This study examined serum vitamin ...
2019-01-24Zeitschriftenartikel
NTCP S267F variant associates with decreased susceptibility to HBV and HDV infection and decelerated progression of related liver diseases 
Binh, Mai Thanh; Xuan Hoan, Nghiem; Van Tong, Hoang; Sy, Bui Tien; Trung, Ngo Tat; Bock, C. Thomas; Toan, Nguyen Linh; Song, Le Huu; Bang, Mai Hong; Meyer, Christian G.; Kremsner, Peter G.; Velavan, Thirumalaisamy P.
Objectives To determine potential associations of the rs2296651 variant (c.800C > T, S267F) of NTCP with HBV and HBV plus concomitant HDV infection as well as with the progression of related liver diseases. Methods The ...
2018-10-03Zeitschriftenartikel
ESBL-Producing Klebsiella pneumoniae in the Broiler Production Chain and the First Description of ST3128 
Daehre, Katrin; Projahn, Michaela; Friese, Anika; Semmler, Torsten; Guenther, Sebastian; Roesler, Uwe H.
ESBL-producing Klebsiella pneumoniae (K. pneumoniae) represent an increasing problem both in human and veterinary medicine. As SHV-2 - encoding K. pneumoniae were recently detected in the broiler production we were interested ...
2019-01-16Zeitschriftenartikel
The cell cycle regulator GpsB functions as cytosolic adaptor for multiple cell wall enzymes 
Cleverley, Robert M.; Rutter, Zoe J.; Rismondo, Jeanine; Corona, Federico; Tsui, Ho-Ching Tiffany; Alatawi, Fuad A.; Daniel, Richard A.; Halbedel, Sven; Massidda, Orietta; Winkler, Malcolm E.; Lewis, Richard J.
Bacterial growth and cell division requires precise spatiotemporal regulation of the synthesis and remodelling of the peptidoglycan layer that surrounds the cytoplasmic membrane. GpsB is a cytosolic protein that affects ...
2019-01-21Zeitschriftenartikel
In vitro comparison of currently available and investigational antiviral agents against pathogenic human double-stranded DNA viruses: A systematic literature review 
Chemaly, Roy F.; Hill, Joshua A.; Voigt, Sebastian; Peggs, Karl S.
Background Double-stranded (ds) DNA virus infections often occur concomitantly in immunocompromised patients. We performed a systematic search of published in vitro activity for nine approved and investigational antivirals ...
2018-12-13Zeitschriftenartikel
Structure-Function Relationship of XCL1 Used for in vivo Targeting of Antigen Into XCR1+ Dendritic Cells 
Kroczek, Arthur L.; Hartung, Evelyn; Gurka, Stephanie; Becker, Martina; Reeg, Nele; Mages, Hans Werner; Voigt, Sebastian; Freund, Christian; Kroczek, Richard
XCL1 is the ligand for XCR1, a chemokine receptor uniquely expressed on crosspresenting dendritic cells (DC) in mouse and man. We are interested in establishing therapeutic vaccines based on XCL1-mediated targeting of ...
2019-01-03Zeitschriftenartikel
Complete Genome Sequence of a Hepatitis E Virus Genotype 1e Strain from an Outbreak in Nigeria, 2017 
Akanbi, Olusola Anuoluwapo; Harms, Dominik; Wang, Bo; Opaleye, Oluyinka Oladele; Adesina, Olufisayo; Osundare, Folakemi Abiodun; Ogunniyi, Abiodun; Naidoo, Dhamari; Devaux, Isabelle; Wondimagegnehu, Alemu; Peter, Clement; Ifeanyi, Okudo; Ogundiran, Opeayo; Ugochukwu, Uzoma; Mba, Nwando; Omilabu, Sunday A.; Ihekweazu, Chikwe; Bock, C. Thomas
Hepatitis E virus genotype 1 (HEV-1) is associated with large epidemics. Notably, HEV subtype 1e (HEV-1e) has caused HEV outbreaks in sub-Saharan Africa. We report here the second full-length genome sequence of an HEV-1e ...
2018-02-22Zeitschriftenartikel
Unterschiede in der subjektiven und psychischen Gesundheit und im Gesundheitsverhalten bei 11- bis 17-jährigen Jugendlichen an weiterführenden Schulen in Deutschland 
Ergebnisse der Studie zur Gesundheit von Kindern und Jugendlichen in Deutschland: Erste Folgebefragung (KiGGS Welle 1)
Waldhauer, Julia; Kuntz, Benjamin; Lampert, Thomas
Hintergrund Bereits im Kindes- und Jugendalter sind gesundheitliche Ungleichheiten zuungunsten sozial benachteiligter Bevölkerungsgruppen festzustellen. Der Beitrag untersucht, inwiefern sich Unterschiede in der subjektiven ...
2018-12-06Zeitschriftenartikel
Quantifying unmet prevention needs among MSM in Europe through a multi-site bio-behavioural survey 
Mirandola, Massimo; Gios, Lorenzo; Sherriff, Nigel; Marcus, Ulrich; Toskin, Igor; Rosinska, Magdalena; Schink, Susanne; Kühlmann-Berenzon, Sharon; Suligoi, Barbara; Folch, Cinta; Nöstlinger, Christiane; Dias, Sonia F.; Stanekova, Danica; Klavs, Irena; Caplinskas, Saulius; Rafila, Alexandru; Marin, Carolina; Alexiev, Ivailo; Zohrabyan, Lev; Noori, Teymur; Menel Lemos, Cinthia
Introduction The HIV epidemic represents an important public health issue in Europe particularly among men who have sex with men (MSM). Global AIDS Monitoring indicators (GAM) have been widely and jointly promoted as a ...
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