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2018-10-04Zeitschriftenartikel

Surveillance on speed: Being aware of infectious diseases in migrants mass accommodations - an easy and flexible toolkit for field application of syndromic surveillance, Germany, 2016 to 2017

Sarma, Navina; Ullrich, Alexander; Wilking, Hendrik; Ghozzi, Stéphane; Lindner, Andreas K.; Weber, Christoph; Holzer, Alexandra; Jansen, Andreas; Stark, Klaus; Vygen-Bonnet, Sabine

Europe received an increased number of migrants in 2015. Housing in inadequate mass accommodations (MA) made migrants prone to infectious disease outbreaks. In order to enhance awareness for infectious diseases (ID) and ...

2019-03-06Zeitschriftenartikel

Diagnosing Zika virus infection against a background of other flaviviruses: Studies in high resolution serological analysis

Hansen, Sören; Hotop, Sven-Kevin; Faye, Oumar; Ndiaye, Oumar; Böhlken-Fascher, Susanne; Pessôa, Rodrigo; Hufert, Frank; Stahl-Hennig, Christiane; Frank, Roland; Czerny, Claus-Peter; Schmidt-Chanasit, Jonas; Sanabani, Sabri S.; Sall, Amadou A.; Niedrig, Matthias; Brönstrup, Mark; Fritz, Hans-Joachim; Abd El Wahed, Ahmed

Zika virus (ZIKV) is a mosquito-borne flavivirus. Homologous proteins of different flaviviruses display high degrees of sequence identity, especially within subgroups. This leads to extensive immunological cross-reactivity ...

2019-03-06Zeitschriftenartikel

Telbivudine Reduces Parvovirus B19-Induced Apoptosis in Circulating Angiogenic Cells

Zobel, Thomas; Bock, C. Thomas; Kühl, Uwe; Rohde, Maria; Lassner, Dirk; Schultheiss, Heinz-Peter; Schmidt-Lucke, Caroline

Aims: Human parvovirus B19 (B19V) infection directly induces apoptosis and modulates CXCR4 expression of infected marrow-derived circulating angiogenic cells (CACs). This leads to dysfunctional endogenous vascular repair. ...

2018-04-10Zeitschriftenartikel

Ebola Outbreak Containment: Real-Time Task and Resource Coordination With SORMAS

Perscheid, Cindy; Benzler, Justus; Hermann, Claus; Janke, Michael; Moyer, David; Laedtke, Todd; Adeoye, Olawunmi; Denecke, Kerstin; Kirchner, Göran; Beermann, Sandra; Schwarz, Norbert; Tom-Aba, Daniel; Krause, Gérard

Background: Since the beginning of the Ebola outbreak in West Africa in 2014, more than 11,000 people died. For outbreaks of infectious diseases like this, the rapid implementation of control measures is a crucial factor ...

2018-01-08Zeitschriftenartikel

A cluster of multidrug-resistant Mycobacterium tuberculosis among patients arriving in Europe from the Horn of Africa: a molecular epidemiological study

Walker, Timothy M.; Merker, Matthias; Knoblauch, Astrid M.; Helbling, Peter; Schoch, Otto D.; van der Werf, Marieke J.; Kranzer, Katharina; Fiebig, Lena; Kröger, Stefan; Haas, Walter; Hoffmann, Harald; Indra, Alexander; Egli, Adrian; Cirillo, Daniela M.; Robert, Jérôme; Rogers, Thomas R.; Groenheit, Ramona; Mengshoel, Anne T.; Mathys, Vanessa; Haanperä, Marjo; van Soolingen, Dick; Niemann, Stefan; Böttger, Erik C.; Keller, Peter M.; MDR-TB Cluster Consortium

Background The risk of tuberculosis outbreaks among people fleeing hardship for refuge in Europe is heightened. We describe the cross-border European response to an outbreak of multidrug-resistant tuberculosis among ...

2018-01-17Zeitschriftenartikel

Environmental adaptation and vertical dissemination of ESBL‐/pAmpC‐producing Escherichia coli in an integrated broiler production chain in the absence of an antibiotic treatment

Projahn, Michaela; Daehre, Katrin; Semmler, Torsten; Guenther, Sebastian; Roesler, Uwe; Friese, Anika

High prevalence numbers of extended-spectrum beta-lactamase- (ESBL-)/plasmid-mediated AmpC beta-lactamase- (pAmpC-) producing Escherichia coli in broiler chicken and their distribution along the broiler production chain ...

2018-02-06Zeitschriftenartikel

Recommendations for enterovirus diagnostics and characterisation within and beyond Europe

Harvala, Heli; Broberg, Eeva; Benschop, Kimberley; Berginc, Natasa; Ladhani, Shamez; Susi, Petri; Christiansen, Claus; McKenna, James; Allen, David; Makiello, Phoebe; McAllister, Georgina; Carmen, Mirabelli; Zakikhany, Katherina; Dyrdak, Robert; Nielsen, Xiaohui; Madsen, Tina; Paul, Joel; Moore, Catherine; von Eije, Karin; Piralla, Antonio; Carlier, Mieke; Vanoverschelde, Laura; Poelman, Randy; Anton, Andrés; López-Labrador, F. Xavier; Pellegrinelli, Laura; Keeren, Kathrin; Maier, Melanie; Cassidy, Hayley; Derdas, Stavros; Savolainen-Kopra, Carita; Diedrich, Sabine; Nordbø, Svein; Buesa, Javier; Bailly, Jean-Luc; Baldanti, Fausto; MacAdam, Andrew; Mirand, Audrey; Dudman, Susanne; Schuffenecker, Isabelle; Kadambari, Seilesh; Neyts, Johan; Griffiths, Michael J.; Richter, Jan; Margaretto, Christina; Govind, Sheila; Morley, Ursula; Adams, Ortwin; Krokstad, Sidsel; Dean, Jonathan; Pons-Salort, Margarita; Prochazka, Birgit; Cabrerizo, Maria; Majumdar, Manasi; Nebbia, Gaia; Wiewel, Maryse; Cottrell, Simon; Coyle, Peter; Martin, Javier; Moore, Catrin; Midgley, Sofie; Horby, Peter; Wolthers, Katja; Simmonds, Peter; Niesters, Hubert; Fischer, Thea K.

Enteroviruses (EV) can cause severe neurological and respiratory infections, and occasionally lead to devastating outbreaks as previously demonstrated with EV-A71 and EV-D68 in Europe. However, these infections are still ...

2017-11-10Zeitschriftenartikel

2015/16 I‐MOVE/I‐MOVE+ multicentre case‐control study in Europe: Moderate vaccine effectiveness estimates against influenza A(H1N1)pdm09 and low estimates against lineage‐mismatched influenza B among children

Kissling, Esther; Valenciano, Marta; Pozo, Francisco; Vilcu, Ana-Maria; Reuss, Annicka; Rizzo, Caterina; Larrauri, Amparo; Horváth, Judit Krisztina; Brytting, Mia; Domegan, Lisa; Korczyńska, Monika; Meijer, Adam; Machado, Ausenda; Ivanciuc, Alina; Višekruna Vučina, Vesna; van der Werf, Sylvie; Schweiger, Brunhilde; Bella, Antonino; Gherasim, Alin; Ferenczi, Annamária; Zakikhany, Katherina; O'Donnell, Joan; Paradowska-Stankiewicz, Iwona; Dijkstra, Frederika; Guiomar, Raquel; Lazar, Mihaela; Kurečić Filipović, Sanja; Johansen, Kari; Moren, Alain; I-MOVE/I-MOVE+ study team

Background During the 2015/16 influenza season in Europe, the cocirculating influenza viruses were A(H1N1)pdm09 and B/Victoria, which was antigenically distinct from the B/Yamagata component in the trivalent influenza ...

2018-04-11Zeitschriftenartikel

Antibiotikaresistenz von E. coli bei ambulant erworbener unkomplizierter Harnwegsinfektion

Eine prospektive Kohortenstudie der Jahre 2015/2016 (SARHA-Studie) im Vergleich mit Daten der Antibiotika-Resistenz-Surveillance (ARS)

Klingeberg, Anja; Noll, Ines; Willrich, Niklas; Feig, Marcel; Emrich, Dagmar; Zill, Edith; Krenz-Weinreich, A.; Kalka-Moll, Wiltrud; Oberdorfer, Klaus; Schmiemann, Guido; Eckmanns, Tim

Hintergrund: Da bei unkomplizierten Harnwegsinfektionen (HWI) keine mikrobiologische Diagnostik empfohlen wird, wird die Resistenzsituation in Bezug auf HWI in Routinedaten nicht angemessen abgebildet. Es wurde die ...

2018-02-01Zeitschriftenartikel

Seasonality and geographical spread of respiratory syncytial virus epidemics in 15 European countries, 2010 to 2016

Broberg, Eeva K.; Waris, Matti; Johansen, Kari; Snacken, René; Penttinen, Pasi; European Influenza Surveillance Network

Respiratory syncytial virus (RSV) is considered the major pathogen causing severe lower respiratory tract infections among infants and young children [1]. RSV is the most common cause of hospitalisation for acute lower ...

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