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2017-11-16Zeitschriftenartikel
Qualitätsstandards für epidemiologische Kohortenstudien 
Ein bewerteter Anforderungskatalog zur Studienvorbereitung und Studiendurchführung
Schmidt, Carsten Oliver; Krabbe, Christine E. M.; Schössow, Janka; Berger, Klaus; Enzenbach, Cornelia; Kamtsiuris, Panagiotis; Schöne, Gina; Houben, Robin; Meisinger, Christa; Bamberg, Fabian; Hendel, Thomas; Selder, Sonja; Nonnemacher, Michael; Moebus, Susanne; Stausberg, Jürgen
Hintergrund Kohortenstudien sind prospektive Beobachtungsstudien. Sie sind in der Epidemiologie zum Studium von Krankheitsverläufen und Risikofaktoren fest etabliert. Hinsichtlich der Beschreibung und Bewertung von ...
2018-10-18Zeitschriftenartikel
Large variation in ESBL-producing Escherichia coli carriers in six European countries including Russia 
Ny, Sofia; Kozlov, Roman; Dumpis, Uga; Edquist, Petra; Gröndahl-Yli-Hannuksela, Kirsi; Kling, Anna-Maria; Lis, Danuta O.; Lübbert, Christoph; Pomorska-Wesołowska, Monika; Palagin, Ivan; Vilde, Aija; Vuopio, Jaana; Walter, Jan; Tegmark Wisell, Karin; NoDARS ESBL-carrier working group
We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects ...
2018-10-23Zeitschriftenartikel
Case report: A fatal case of cryptococcosis in an immunocompetent patient due to Cryptococcus deuterogattii (AFLP6/VGII) 
Bauer, M.; Wickenhauser, C.; Haak, A.; Pazaitis, N.; Siebolts, U.; Mawrin, C.; Strauss, C.; Rickerts, V.; Stoevesandt, D.; Cornely, O. A.; Meis, J. F.; Hagen, F.
Introduction. Cryptococcosis in immunocompetent adults is a rare disease in Europe, mostly induced by members of the Cryptococcus gattii species complex. The diagnosis can be challenging due to its rarity, unspecific ...
2017-11-27Zeitschriftenartikel
Gesundheit: Die Region im Fokus 
Kuhn, Joseph; Saß, Anke-Christine
2018-10-18Zeitschriftenartikel
Pathways of host cell exit by intracellular pathogens 
Flieger, Antje; Frischknecht, Freddy; Häcker, Georg; Hornef, Mathias W.; Pradel, Gabriele
Host cell exit is a critical step in the life-cycle of intracellular pathogens, intimately linked to barrier penetration, tissue dissemination, inflammation, and pathogen transmission. Like cell invasion and intracellular ...
2018-09-10Zeitschriftenartikel
Comparative Secretome Analyses of Human and Zoonotic Staphylococcus aureus Isolates CC8, CC22, and CC398 
Busche, Tobias; Hillion, Mélanie; Van Loi, Vu; Berg, David; Walther, Birgit; Semmler, Torsten; Strommenger, Birgit; Witte, Wolfgang; Cuny, Christiane; Mellmann, Alexander; Holmes, Mark A.; Kalinowski, Jörn; Adrian, Lorenz; Bernhardt, Jörg; Antelmann, Haike
The spread of methicillin-resistant Staphylococcus aureus (MRSA) in the community, hospitals and in livestock is mediated by highly diverse virulence factors that include secreted toxins, superantigens, enzymes and ...
2019-02-11Zeitschriftenartikel
Limits of Life and the Habitability of Mars: The ESA Space Experiment BIOMEX on the ISS 
de Vera, Jean-Pierre; Alawi, Mashal; Backhaus, Theresa; Baqué, Mickael; Billi, Daniela; Böttger, Ute; Berger, Thomas; Bohmeier, Maria; Cockell, Charles; Demets, René; de la Torre Noetzel, Rosa; Edwards, Howell; Elsaesser, Andreas; Fagliarone, Claudia; Fiedler, Annelie; Foing, Bernard; Foucher, Frédéric; Fritz, Jörg; Hanke, Franziska; Herzog, Thomas; Horneck, Gerda; Hübers, Heinz-Wilhelm; Huwe, Björn; Joshi, Jasmin; Kozyrovska, Natalia; Kruchten, Martha; Lasch, Peter; Lee, Natuschka; Leuko, Stefan; Leya, Thomas; Lorek, Andreas; Martínez-Frías, Jesús; Meessen, Joachim; Moritz, Sophie; Moeller, Ralf; Olsson-Francis, Karen; Onofri, Silvano; Ott, Sieglinde; Pacelli, Claudia; Podolich, Olga; Rabbow, Elke; Reitz, Günther; Rettberg, Petra; Reva, Oleg; Rothschild, Lynn; Garcia Sancho, Leo; Schulze-Makuch, Dirk; Selbmann, Laura; Serrano, Paloma; Szewzyk, Ulrich; Verseux, Cyprien; Wadsworth, Jennifer; Wagner, Dirk; Westall, Frances; Wolter, David; Zucconi, Laura
BIOMEX (BIOlogy and Mars EXperiment) is an ESA/Roscosmos space exposure experiment housed within the exposure facility EXPOSE-R2 outside the Zvezda module on the International Space Station (ISS). The design of the ...
2019-03-05Zeitschriftenartikel
From Entry to Early Dissemination—Toxoplasma gondii's Initial Encounter With Its Host 
Delgado Betancourt, Estefania; Hamid, Benjamin; Fabian, Benedikt T.; Klotz, Christian; Hartmann, Susanne; Seeber, Frank
Toxoplasma gondii is a zoonotic intracellular parasite, able to infect any warm-blooded animal via ingestion of infective stages, either contained in tissue cysts or oocysts released into the environment. While immune ...
2019-02-21Zeitschriftenartikel
No evidence of carbapenemase-producing Enterobacteriaceae in stool samples of 1,544 asylum seekers arriving in Rhineland-Palatinate, Germany, April 2016 to March, 2017 
Ehlkes, Lutz; Pfeifer, Yvonne; Werner, Guido; Ignatius, Ralf; Vogt, Manfred; Eckmanns, Tim; Zanger, Philipp; Walter, Jan
Introduction: Since 2015, increased migration from Asia and Africa to Europe has raised public health concerns about potential importation of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE), specifically ...
2019-01-16Zeitschriftenartikel
A Listeria monocytogenes ST2 clone lacking chitinase ChiB from an outbreak of non-invasive gastroenteritis 
Halbedel, Sven; Prager, Rita; Kleta, Sylvia; Trost, Eva; Nishanth, Gopala; Alles, Georg; Hölzel, Christina; Schlesiger, Friederike; Pietzka, Ariane; Schlüter, Dirk; Flieger, Antje; Banerji, Sangeeta
An outbreak with a remarkable Listeria monocytogenes clone causing 163 cases of non-invasive listeriosis occurred in Germany in 2015. Core genome multi locus sequence typing grouped non-invasive outbreak isolates and ...
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