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2019-06-12Zeitschriftenartikel
First-line tuberculosis drug resistance patterns and associated risk factors in Germany, 2008-2017 
Glasauer, Saskia; Altmann, Doris; Hauer, Barbara; Brodhun, Bonita; Haas, Walter; Perumal, Nita
Background Drug-resistant tuberculosis (TB), especially multidrug-resistant TB (MDR-TB), poses a threat to public health. While standard surveillance focuses on Rifampicin and/or Isoniazid resistance, little is known about ...
2019-06-21Zeitschriftenartikel
Perceived diabetes risk and related determinants in individuals with high actual diabetes risk: results from a nationwide population-based survey 
Heidemann, Christin; Paprott, Rebecca; Stühmann, Lena M.; Baumert, Jens; Mühlenbruch, Kristin; Hansen, Sylvia; Schiborn, Catarina; Zahn, Daniela; Gellert, Paul; Scheidt-Nave, Christa
Objective The purpose of this study was first, to examine perceived diabetes risk compared with actual diabetes risk in the general population and second, to investigate which factors determine whether persons at increased ...
2019-07-31Zeitschriftenartikel
Whole genome-based public health surveillance of less common STEC serovars and untypable strains identifies four novel O genotypes 
Lang, Christina; Hiller, Miriam; Konrad, Regina; Fruth, Angelika; Flieger, Antje
Shiga toxin-producing E. coli (STEC) and the subgroup of enterohemorrhagic E. coli cause intestinal infections with symptoms ranging from watery diarrhea to hemolytic uremic syndrome (HUS). A key tool for epidemiological ...
2018-09-06Zeitschriftenartikel
National public health system responses to diabetes and other important noncommunicable diseases 
Background, goals, and results of an international workshop at the Robert Koch Institute
Reitzle, Lukas; Hansen, Sylvia; Paprott, Rebecca; Achtermann, Wally; Baumert, Jens; Bogaert, Petronille; Curt, Laure; Diem, Peter; Du, Yong; Eiser, Stefanie; Fitzpatrick, Justine; Heidemann, Christin; Jousilahti, Pekka; Kulzer, Bernhard; Lindström, Jaana; Neuhauser, Hannelore; van Oyen, Herman; Pelletier, Louise; Schmidt, Christian; Valabhji, Jonathan; Weitgasser, Raimund; Ziese, Thomas; Zahn, Daniela; Scheidt-Nave, Christa
Diabetes mellitus and other noncommunicable diseases (NCDs) represent an emerging global public health challenge. In Germany, about 6.7 million adults are affected by diabetes according to national health surveys, including ...
2019-08-13Zeitschriftenartikel
Epidemiology and cost of seasonal influenza in Germany - a claims data analysis 
Scholz, Stefan; Damm, Oliver; Schneider, Udo; Ultsch, Bernhard; Wichmann, Ole; Greiner, Wolfgang
Background Seasonal influenza contributes substantially to the burden of communicable diseases in Europe, especially among paediatric populations and the elderly. The aim of the present study was to estimate the incidence ...
2019-06-04Zeitschriftenartikel
Maternal Immunization and Antenatal Care Situation Analysis (MIACSA) study protocol: a multiregional, cross-sectional analysis of maternal immunization delivery strategies to reduce maternal and neonatal morbidity and mortality 
Roos, Nathalie; Lambach, Philipp; Mantel, Carsten; Mason, Elizabeth; Muñoz, Flor M.; Giles, Michelle; Moran, Allisyn; Hombach, Joachim; Diaz, Theresa; MIACSA expert advisory panel group
Introduction Maternal immunization (MI) with tetanus toxoid containing vaccine, is a safe and cost-effective way of preventing neonatal tetanus. Given the prospect of introducing new maternal vaccines in the near ...
2019-08-06Zeitschriftenartikel
Cell Shape and Antibiotic Resistance Are Maintained by the Activity of Multiple FtsW and RodA Enzymes in Listeria monocytogenes 
Rismondo, Jeanine; Halbedel, Sven; Gründling, Angelika
Rod-shaped bacteria have two modes of peptidoglycan synthesis: lateral synthesis and synthesis at the cell division site. These two processes are controlled by two macromolecular protein complexes, the elongasome and ...
2019-04-26Zeitschriftenartikel
eDiVA—Classification and prioritization of pathogenic variants for clinical diagnostics 
Bosio, Mattia; Drechsel, Oliver; Rahman, Rubayte; Muyas, Francesc; Rabionet, Raquel; Bezdan, Daniela; Domenech Salgado, Laura; Hor, Hyun; Schott, Jean-Jacques; Munell, Francina; Colobran, Roger; Macaya, Alfons; Estivill, Xavier; Ossowski, Stephan
Mendelian diseases have shown to be an and efficient model for connecting genotypes to phenotypes and for elucidating the function of genes. Whole‐exome sequencing (WES) accelerated the study of rare Mendelian diseases in ...
2019-08-30Zeitschriftenartikel
Effects of preschoolers’ storybook exposure and literacy environments on lower level and higher level language skills 
Grolig, Lorenz; Cohrdes, Caroline; Tiffin-Richards, Simon P.; Schroeder, Sascha
The development of preschoolers’ language skills is influenced by literacy environments and individual differences in storybook exposure. Extant research is limited as most studies (a) investigate the effects on lower level ...
2019-06-06Zeitschriftenartikel
Partnering for enhanced digital surveillance of influenza‐like disease and the effect of antivirals and vaccines (PEDSIDEA) 
Rath, Barbara; Maltezou, Helena C.; Papaevangelou, Vassiliki; Papagrigoriou‐Theodoridou, Maria‐Alexandra; Alchikh, Maren; Myles, Puja; Schweiger, Brunhilde; PEDSIDEA Network
Background Standardised clinical outcome measures are urgently needed for the surveillance of influenza and influenza‐like illness (ILI) based on individual patient data (IPD). Objectives We report a multicentre prospective ...
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