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2019-09-02Zeitschriftenartikel
Influenza and pertussis vaccination during pregnancy – attitudes, practices and barriers in gynaecological practices in Germany 
Böhm, Stefanie; Röbl-Mathieu, Marianne; Scheele, Burkhard; Wojcinski, Michael; Wichmann, Ole; Hellenbrand, Wiebke
Background In Germany, antenatal influenza vaccination is recommended since 2010, but uptake remains low. Several countries recently introduced antenatal pertussis vaccination, which is currently under consideration in ...
2019-08-28Zeitschriftenartikel
The rise in vancomycin-resistant Enterococcus faecium in Germany: data from the German Antimicrobial Resistance Surveillance (ARS) 
Markwart, Robby; Willrich, Niklas; Haller, Sebastian; Noll, Ines; Koppe, Uwe; Werner, Guido; Eckmanns, Tim; Reuss, Annicka
Background Due to limited therapeutic options, vancomycin-resistant Enterococcus faecium (VREF) is of great clinical significance. Recently, rising proportions of vancomycin resistance in enterococcal infections have been ...
2019-08-12Zeitschriftenartikel
Detection of Anti-Toxoplasma gondii Antibodies in Human Sera Using Synthetic Glycosylphosphatidylinositol Glycans on a Bead-Based Multiplex Assay 
Garg, Monika; Stern, Daniel; Groß, Uwe; Seeberger, Peter H.; Seeber, Frank; Silva, Daniel Varón
Toxoplasmosis, while often an asymptomatic parasitic disease in healthy individuals, can cause severe complications in immunocompromised persons and during pregnancy. The most common method to diagnose Toxoplasma gondii ...
2019-07-17Zeitschriftenartikel
Epidemiology of Human Parechovirus Type 3 Upsurge in 2 Hospitals, Freiburg, Germany, 2018 
Elling, Roland; Böttcher, Sindy; du Bois, Florian; Müller, Alexandra; Prifert, Christiane; Weissbrich, Benedikt; Hofmann, Jörg; Korn, Klaus; Eis-Hübinger, Anna-Maria; Hufnagel, Markus; Panning, Marcus
In 2018, a cluster of pediatric human parechovirus (HPeV) infections in 2 neighboring German hospitals was detected. Viral protein 1 sequence analysis demonstrated co-circulation of different HPeV-3 sublineages and of ...
2019-11-13Zeitschriftenartikel
The gut microbiome of horses: current research on equine enteral microbiota and future perspectives 
Kauter, Anne; Epping, Lennard; Semmler, Torsten; Antao, Esther-Maria; Kannapin, Dania; Stoeckle, Sabita D.; Gehlen, Heidrun; Lübke-Becker, Antina; Günther, Sebastian; Wieler, Lothar H.; Walther, Birgit
Understanding the complex interactions of microbial communities including bacteria, archaea, parasites, viruses and fungi of the gastrointestinal tract (GIT) associated with states of either health or disease is still an ...
2019-11-28Zeitschriftenartikel
Effects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs 
Johanns, Vanessa C.; Ghazisaeedi, Fereshteh; Epping, Lennard; Semmler, Torsten; Lübke-Becker, Antina; Pfeifer, Yvonne; Bethe, Astrid; Eichhorn, Inga; Merle, Roswitha; Walther, Birgit; Wieler, Lothar H.
Strategies to reduce economic losses associated with post-weaning diarrhea in pig farming include high-level dietary zinc oxide supplementation. However, excessive usage of zinc oxide in the pig production sector was found ...
2019-08-16Zeitschriftenartikel
A Robust and Universal Metaproteomics Workflow for Research Studies and Routine Diagnostics Within 24 h Using Phenol Extraction, FASP Digest, and the MetaProteomeAnalyzer 
Heyer, Robert; Schallert, Kay; Büdel, Anja; Zoun, Roman; Dorl, Sebastian; Behne, Alexander; Kohrs, Fabian; Püttker, Sebastian; Siewert, Corina; Muth, Thilo; Saake, Gunter; Reichl, Udo; Benndorf, Dirk
The investigation of microbial proteins by mass spectrometry (metaproteomics) is a key technology for simultaneously assessing the taxonomic composition and the functionality of microbial communities in medical, environmental, ...
2019-09-14Zeitschriftenartikel
Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages 
Bourquain, Daniel; Bodenstein, Clemens; Schürer, Stefanie; Schaade, Lars
Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS. Tula virus (TULV) is also widely ...
2019-07-09Zeitschriftenartikel
Recursive feature elimination in random forest classification supports nanomaterial grouping 
Bahl, Aileen; Hellack, Bryan; Balas, Mihaela; Dinischiotu, Anca; Wiemann, Martin; Brinkmann, Joep; Luch, Andreas; Renard, Bernhard Y.; Haase, Andrea
Nanomaterials (NMs) can be produced in numerous different variants of the same chemical substance. An in-depth safety assessment for each variant by generating test data will simply not be feasible. Thus, NM grouping ...
2019-09-26Zeitschriftenartikel
Osmolyte homeostasis controls single-cell growth rate and maximum cell size of Saccharomyces cerevisiae 
Altenburg, Tom; Goldenbogen, Björn; Uhlendorf, Jannis; Klipp, Edda
Cell growth is well described at the population level, but precisely how nutrient and water uptake and cell wall expansion drive the growth of single cells is poorly understood. Supported by measurements of single-cell ...
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