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2019-10-29Zeitschriftenartikel
Fly-derived DNA and camera traps are complementary tools for assessing mammalian biodiversity 
Gogarten, Jan F.; Hoffmann, Constanze; Arandjelovic, Mimi; Sachse, Andreas; Merkel, Kevin; Dieguez, Paula; Agbor, Anthony; Angedakin, Samuel; Brazzola, Gregory; Jones, Sorrel; Langergraber, Kevin E.; Lee, Kevin; Marrocoli, Sergio; Murai, Mizuki; Sommer, Volker; Kühl, Hjalmar; Leendertz, Fabian H.; Calvignac-Spencer, Sèbastien
Background Metabarcoding of vertebrate DNA found in invertebrates (iDNA) represents a potentially powerful tool for monitoring biodiversity. Preliminary evidence suggests fly iDNA biodiversity assessments compare favorably ...
2021-03-31Zeitschriftenartikel
Maßnahmen zur Bewältigung der COVID-19-Pandemie in Deutschland: nichtpharmakologische und pharmakologische Ansätze 
Grote, Ulrike; Arvand, Mardjan; Brinkwirth, Simon; Brunke, Melanie; Buchholz, Udo; Eckmanns, Tim; von Kleist, Max; Niebank, Michaela; Ruehe, Bettina; Schulze, Kai; Stoliaroff-Pépin, Anna; Thanheiser, Marc; Schaade, Lars; Said, Dunja; Haas, Walter
Beim ersten Auftreten des Erregers SARS-CoV‑2 im Dezember 2019 standen weder spezifische therapeutische Möglichkeiten noch ein Impfstoff zur Verfügung. Auch in Deutschland rückten deshalb nichtpharmakologische Maßnahmen ...
2021-04-20Zeitschriftenartikel
An intra-host SARS-CoV-2 dynamics model to assess testing and quarantine strategies for incoming travelers, contact management, and de-isolation 
van der Toorn, Wiep; Oh, Djin-Ye; Bourquain, Daniel; Michel, Janine; Krause, Eva; Nitsche, Andreas; von Kleist, Max
Non-pharmaceutical interventions (NPIs) remain decisive tools to contain SARS-CoV-2. Strategies that combine NPIs with testing may improve efficacy and shorten quarantine durations. We developed a stochastic within-host ...
2021-05-14Zeitschriftenartikel
Disease surveillance for the COVID-19 era: time for bold changes 
Morgan, Oliver W; Aguilera, Ximena; Ammon, Andrea; Amuasi, John; Fall, Ibrahima Socé; Frieden, Tom; Heymann, David; Ihekweazu, Chikwe; Jeong, Eun-kyeong; Leung, Gabriel M; Mahon, Barbara; Nkengasong, John; Qamar, Farah Naz; Schuchat, Anne; Wieler, Lothar H; Dowell, Scott F
The COVID-19 pandemic has exposed weaknesses in disease surveillance in nearly all countries. Early identification of COVID-19 cases and clusters for rapid containment was hampered by inadequate diagnostic capacity, ...
2021-02-22Zeitschriftenartikel
Application of spectral library prediction for parallel reaction monitoring of viral peptides 
Grossegesse, Marica; Nitsche, Andreas; Schaade, Lars; Döllinger, Jörg
A major part of the analysis of parallel reaction monitoring (PRM) data is the comparison of observed fragment ion intensities to a library spectrum. Classically, these libraries are generated by data-dependent acquisition ...
2021-06-05Zeitschriftenartikel
Comparison of self-reported & device-based, measured physical activity among children in Germany 
Burchartz, Alexander; Oriwol, Doris; Kolb, Simon; Schmidt, Steffen C. E.; Wunsch, Kathrin; Manz, Kristin; Niessner, Claudia; Woll, Alexander
As children show a more complex but less structured movement behavior than adults, assessment of their many spontaneous and impulsive movements is a challenge for physical activity (PA) assessment. Since neither questionnaires ...
2021-06-01Zeitschriftenartikel
Towards the characterization of the hidden world of small proteins in Staphylococcus aureus, a proteogenomics approach 
Fuchs, Stephan; Kucklick, Martin; Lehmann, Erik; Beckmann, Alexander; Wilkens, Maya; Kolte, Baban; Mustafayeva, Ayten; Ludwig, Tobias; Diwo, Maurice; Wissing, Josef; Jänsch, Lothar; Ahrens, Christian H.; Ignatova, Zoya; Engelmann, Susanne
Small proteins play essential roles in bacterial physiology and virulence, however, automated algorithms for genome annotation are often not yet able to accurately predict the corresponding genes. The accuracy and reliability ...
2021-06-08Zeitschriftenartikel
“How Come You Don’t Call Me?” Smartphone Communication App Usage as an Indicator of Loneliness and Social Well-Being across the Adult Lifespan during the COVID-19 Pandemic 
Wetzel, Britta; Pryss, Rüdiger; Baumeister, Harald; Edler, Johanna-Sophie; Gonçalves, Ana Sofia Oliveira; Cohrdes, Caroline
Loneliness and lack of social well-being are associated with adverse health outcomes and have increased during the COVID-19 pandemic. Smartphone communication data have been suggested to help monitor loneliness, but this ...
2021-05-31Zeitschriftenartikel
Real-time monitoring of COVID-19 dynamics using automated trend fitting and anomaly detection 
Jombart, Thibaut; Ghozzi, Stéphane; Schumacher, Dirk; Taylor, Timothy J.; Leclerc, Quentin J.; Jit, Mark; Flasche, Stefan; Greaves, Felix; Ward, Tom; Eggo, Rosalind M.; Nightingale, Emily; Meakin, Sophie; Brady, Oliver J.
As several countries gradually release social distancing measures, rapid detection of new localized COVID-19 hotspots and subsequent intervention will be key to avoiding large-scale resurgence of transmission. We introduce ...
2021-05-16Zeitschriftenartikel
A Pilot Randomised Clinical Trial Comparing a Short-Term Perioperative Prophylaxis Regimen to a Long-Term Standard Protocol in Equine Colic Surgery 
Stöckle, Sabita Diana; Kannapin, Dania A.; Kauter, Anne M. L.; Lübke-Becker, Antina; Walther, Birgit; Merle, Roswitha; Gehlen, Heidrun
For surgical interventions classified as clean or clean-contaminated, including laparotomy, guidelines in human and veterinary medicine recommend a short-term perioperative antibiotic prophylaxis (PAP). In equine colic ...
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