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2020-12-29Zeitschriftenartikel

COVID-19 lockdown induces disease-mitigating structural changes in mobility networks

Schlosser, Frank; Maier, Benjamin F.; Jack, Olivia; Hinrichs, David; Zachariae, Adrian; Brockmann, Dirk

In the wake of the COVID-19 pandemic many countries implemented containment measures to reduce disease transmission. Studies using digital data sources show that the mobility of individuals was effectively reduced in ...

2020-12-09Zeitschriftenartikel

Variable Sensitivity of SARS-CoV-2 Molecular Detection in European Expert Laboratories: External Quality Assessment, June and July 2020

Fischer, Carlo; Mögling, Ramona; Melidou, Angeliki; Kühne, Arne; Oliveira-Filho, Edmilson F.; Wolff, Thorsten; Reiche, Janine; Broberg, Eeva; Drosten, Christian; Meijer, Adam; Leitmeyer, Katrin; Drexler, Jan Felix; Reusken, Chantal B.E.M.

During the ongoing coronavirus disease 2019 (COVID-19) outbreak, robust detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a key element for clinical management and to interrupt transmission chains. ...

2020-12-15Zeitschriftenartikel

COVID-19 in Central Asia: Uzbekistan's new approach to international cooperation

Shadmanov, Alisher; Boklage, Evgeniya; Storozhenko, Oleg; Jansen, Andreas

The COVID-19 pandemic is not only a challenge to public health structures and economies but also a touchstone for international solidarity. Due to the implicit cross-border nature of the outbreak, the international health ...

2020-11-30Zeitschriftenartikel

Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19

Meinhardt, Jenny; Radke, Josefine; Dittmayer, Carsten; Franz, Jonas; Thomas, Carolina; Mothes, Ronja; Laue, Michael; Schneider, Julia; Brünink, Sebastian; Greuel, Selina; Lehmann, Malte; Hassan, Olga; Aschman, Tom; Schumann, Elisa; Chua, Robert Lorenz; Conrad, Christian; Eils, Roland; Stenzel, Werner; Windgassen, Marc; Rößler, Larissa; Goebel, Hans-Hilmar; Gelderblom, Hans R.; Martin, Hubert; Nitsche, Andreas; Schulz-Schaeffer, Walter J.; Hakroush, Samy; Winkler, Martin S.; Tampe, Björn; Scheibe, Franziska; Körtvélyessy, Péter; Reinhold, Dirk; SIegmund, Britta; Kühl, Anja A.; Elezkurtaj, Sefer; Horst, David; Oesterhelweg, Lars; Tsokos, Michael; Ingold-Heppner, Barbara; Stadelmann, Christine; Drosten, Christian; Radbruch, Helena; Heppner, Frank L.; Corman, Victor Max

The newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19, a pandemic respiratory disease. Moreover, thromboembolic events throughout the body, including in the CNS, have been ...

2020-11-04Zeitschriftenartikel

Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research

Hufsky, Franziska; Lamkiewicz, Kevin; Almeida, Alexandre; Aouacheria, Abdel; Arighi, Cecilia; Bateman, Alex; Baumbach, Jan; Beerenwinkel, Niko; Brandt, Christian; Cacciabue, Marco; Chuguransky, Sara; Drechsel, Oliver; Finn, Robert D; Fritz, Adrian; Fuchs, Stephan; Hattab, Georges; Hauschild, Anne-Christin; Heider, Dominik; Hoffmann, Marie; Hölzer, Martin; Hoops, Stefan; Kaderali, Lars; Kalvari, Ioanna; von Kleist, Max; Kmiecinski, Renó; Kühnert, Denise; Lasso, Gorka; Libin, Pieter; List, Markus; Löchel, Hannah F.; Martin, Maria J.; Martin, Roman; Matschinske, Julian; McHardy, Alice C.; Mendes, Pedro; Mistry, Jaina; Navratil, Vincent; Nawrocki, Eric P.; O'Toole, Áine Niamh; Ontiveros-Palacios, Nancy; Petrov, Anton I; Rangel-Pineros, Guillermo; Redaschi, Nicole; Reimering, Susanne; Reinert, Knut; Reyes, Alejandro; RIchardson, Lorna; Robertson, David L.; Sadegh, Sepideh; Singer, Joshua B.; Theys, Kristof; Upton, Chris; Welzel, Marius; Williams, Lowri; Marz, Manja

SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. ...

2020-11-19Zeitschriftenartikel

Assessing COVID-19 through the lens of health systems’ preparedness: time for a change

El Bcheraoui, Charbel; Weishaar, Heide; Pozo-Martin, Francisco; Hanefeld, Johanna

The last months have left no-one in doubt that the COVID-19 pandemic is exerting enormous pressure on health systems around the world, bringing to light the sub-optimal resilience of even those classified as high-performing. ...

2020-11-05Zeitschriftenartikel

How to Determine When SARS-CoV-2 Antibody Testing Is or Is Not Useful for Population Screening: A Tutorial

Keller, Niklas; Jenny, Mirjam A.

Extensive testing lies at the heart of any strategy to effectively combat the SARS-COV-2 pandemic. In recent months, the use of enzyme-linked immunosorbent assay–based antibody tests has gained a lot of attention. These ...

2020-11-05Zeitschriftenartikel

Psychische Gesundheit und Lebensqualität von Kindern und Jugendlichen während der COVID-19-Pandemie – Ergebnisse der COPSY-Studie

Ravens-Sieberer, Ulrike; Kaman, Anne; Otto, Christiane; Adedeji, Adekunle; Devine, Janine; Erhart, Michael; Napp, Ann-Kathrin; Becker, Marcia; Blank-Stellenmacher, Ulrike; Löffler, Constanze; Schlack, Robert; Hurrelmann, Klaus

Kinder und Jugendliche sind entwicklungsbedingt vulnerabel, weshalb die COVID-19-bedingten Kontaktbeschränkungen für sie besonders belastend sein können (1, 2). Vor diesem Hintergrund wurde die bundesweite COPSY-Studie ...

2020-11-20Zeitschriftenartikel

SARS-CoV-2: Testergebnisse richtig einordnen

Lein, Ines; Leuker, Christina; Antão, Esther-Maria; von Kleist, Max; Jenny, Mirjam A.

Diagnostische Antigen-Tests („Schnelltests“) können dabei helfen, akut mit SARS-CoV-2 infizierte Personen zu identifizieren. Sie weisen SARS-CoV-2-Proteine nach und sind schneller und preiswerter als PCR-Tests. Gegenwärtig ...

2021-07-23Zeitschriftenartikel

Soziale Ungleichheit in der regionalen Ausbreitung von SARS-CoV-2

Dragano, Nico; Hoebel, Jens; Wachtler, Benjamin; Diercke, Michaela; Lunau, Thorsten; Wahrendorf, Morten

Hintergrund und Ziel: Ob sozioökonomische Faktoren die Ausbreitung von SARS-CoV‑2 beeinflussen, ist nicht ausreichend beantwortet, da frühere Studien in der Regel kumulative Inzidenzen betrachtet und die zeitliche ...

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