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2021-07-21Zeitschriftenartikel

Rise and Fall of SARS-CoV-2 Lineage A.27 in Germany

Calvignac-Spencer, Sébastien; Budt, Matthias; Huska, Matthew; Richard, Hugues; Leipold, Luca; Grabenhenrich, Linus; Semmler, Torsten; von Kleist, Max; Kröger, Stefan; Wolff, Thorsten; Hölzer, Martin

Here, we report on the increasing frequency of the SARS-CoV-2 lineage A.27 in Germany during the first months of 2021. Genomic surveillance identified 710 A.27 genomes in Germany as of 2 May 2021, with a vast majority ...

2021-07-18Zeitschriftenartikel

The Neural Gut–Brain Axis of Pathological Protein Aggregation in Parkinson’s Disease and Its Counterpart in Peroral Prion Infections

Beekes, Michael

A neuropathological hallmark of Parkinson’s disease (PD) is the cerebral deposition of abnormally aggregated α-synuclein (αSyn). PD-associated αSyn (αSynPD) aggregates are assumed to act, in a prion-like manner, as ...

2021-07-10Zeitschriftenartikel

Participation in structured diabetes self-management education programs and its associations with self-management behaviour – a nationwide population-based study

Carmienke, Solveig; Fink, Astrid; Baumert, Jens; Heidemann, Christin; Du, Yong; Frese, Thomas; Heise, Marcus

Objective: To evaluate the relationship between participation in structured diabetes self-management education programs (DSME) and self-management behaviour (SMB) in routine care. Methods: The study included 864 ever- ...

2021-07-23Zeitschriftenartikel

COVID-19-Forschungsdaten leichter zugänglich machen – Aufbau einer bundesweiten Informationsinfrastruktur

Schmidt, Carsten Oliver; Fluck, Juliane; Golebiewski, Martin; Grabenhenrich, Linus; Hahn, Horst; Kirsten, Toralf; Klammt, Sebastian; Löbe, Matthias; Sax, Ulrich; Thun, Sylvia; Pigeot, Iris; Task Force Covid-19, NFDI4Health

Public-Health-Forschung, epidemiologische und klinische Studien sind erforderlich, um die COVID-19-Pandemie besser zu verstehen und geeignete Maßnahmen zu ergreifen. Daher wurden auch in Deutschland zahlreiche Forschungsprojekte ...

2021-07-19Zeitschriftenartikel

Perceived Access to Health Care Services and Relevance of Telemedicine during the COVID-19 Pandemic in Germany

Reitzle, Lukas; Schmidt, Christian; Färber, Francesca; Huebl, Lena; Wieler, Lothar Heinz; Ziese, Thomas; Heidemann, Christin

During the COVID-19 pandemic in Germany, non-pharmaceutical interventions were imposed to contain the spread of the virus. Based on cross-sectional waves in March, July and December 2020 of the COVID-19 Snapshot Monitoring ...

2021-06-24Zeitschriftenartikel

Primary and pollen-associated hazelnut allergy in school-aged children in Germany: A birth cohort study

Erhard, Sina M.; Bellach, Johanna; Yürek, Songül; Tschirner, Sebastian; Trendelenburg, Valérie; Grabenhenrich, Linus B.; Fernandez-Rivas, Montserrat; van Ree, Ronald; Keil, Thomas; Beyer, Kirsten

Background: Primary hazelnut allergy is a common cause of anaphylaxis in children, as compared to birch-pollen associated hazelnut allergy. Population-based data on hazelnut and concomitant birch-pollen allergy in children ...

2021-06-08Zeitschriftenartikel

Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Schwarz, Tatjana; Tober-Lau, Pinkus; Hillus, David; Helbig, Elisa T.; Lippert, Lena J.; Thibeault, Charlotte; Koch, Willi; Landgraf, Irmgard; Michel, Janine; Bergfeld, Leon; Niemeyer, Daniela; Mühlemann, Barbara; Conrad, Claudia; Dang-Heine, Chantip; Kasper, Stefanie; Münn, Friederike; Kappert, Kai; Nitsche, Andreas; Tauber, Rudolf; Schmidt, Sein; Kopankiewicz, Piotr; Bias, Harald; Seybold, Joachim; von Kalle, Christof; Jones, Terry C.; Suttorp, Norbert; Drosten, Christian; Sander, Leif Erik; Corman, Victor M.; Kurth, Florian

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in Germany. These data emphasize ...

2021-07-02Zeitschriftenartikel

Factors preventing SARS-CoV-2 transmission during unintentional exposure in a GP practice: a cohort study of patient contacts; Germany, 2020

Boender, T. Sonia; Bender, Jennifer K.; Krüger, Angelika; Michaelis, Kai; Buchholz, Udo

Two general practitioners (GPs) with SARS-CoV-2 infection provided in-person patient care to patients of their joint medical practice before and after symptom onset, up until SARS CoV-2 laboratory confirmation. Through ...

2021-08-10Zeitschriftenartikel

Die verschiedenen Phasen der COVID-19-Pandemie in Deutschland: Eine deskriptive Analyse von Januar 2020 bis Februar 2021

Schilling, Julia; Tolksdorf, Kristin; Marquis, Adine; Faber, Mirko; Pfoch, Thomas; Buda, Silke; Haas, Walter; Schuler, Ekkehard; Altmann, Doris; Grote, Ulrike; Diercke, Michaela; RKI COVID-19 Study Group

Am 27.01.2020 wurde in Deutschland der erste Fall mit einer SARS-CoV-2-Infektion diagnostiziert. Für die Beschreibung des Pandemieverlaufs im Jahr 2020 wurden 4 epidemiologisch verschiedene Phasen betrachtet und Daten aus ...

2021-07-29Zeitschriftenartikel

SARS-CoV-2-Übertragungswege und Implikationen für den Selbst- und Fremdschutz

Oh, Djin-Ye; Böttcher, Sindy; Kröger, Stefan; von Kleist, Max

Die weltweite Ausbreitung des Coronavirus SARS-CoV‑2 hat Gesundheits‑, Wirtschafts- und Gesellschaftssysteme massiv in Mitleidenschaft gezogen. Obwohl mittlerweile effektive Impfstoffe zur Verfügung stehen, ist es ...

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