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2020-10-16Zeitschriftenartikel
Impact of porcine cytomegalovirus on long‑term orthotopic cardiac xenotransplant survival 
Denner, Joachim; Längin, Matthias; Reichart, Bruno; Krüger, Luise; Fiebig, Uwe; Mokelke, Maren; Radan, Julia; Mayr, Tanja; Milusev, Anastasia; Luther, Fabian; Sorvillo, Nicoletta; Rieben, Robert; Brenner, Paolo; Walz, Christoph; Wolf, Eckhard; Roshani, Berit; Stahl‑Hennig, Christiane; Abicht, Jan‑Michael
Xenotransplantation using pig organs has achieved survival times up to 195 days in pig orthotopic heart transplantation into baboons. Here we demonstrate that in addition to an improved immunosuppressive regimen, non-ischaemic ...
2021-03-17Zeitschriftenartikel
Hunting and consumption of rodents by children in the Lassa fever endemic area of Faranah, Guinea 
Douno, Moussa; Asampong, Emmanuel; Magassouba, N’Faly; Fichet-Calvet, Elisabeth; Almudena, Marí Sáez
As a consequence of the Ebola outbreak, human–animal contact has gained importance for zoonotic transmission surveillance. In Faranah (Upper Guinea), daily life is intertwined with rodents, such as the Natal multimammate ...
2020-11-16Zeitschriftenartikel
Health-related quality of life in children and adolescents with overweight and obesity: results from the German KIGGS survey 
Meixner, Lara; Cohrdes, Caroline; Schienkiewitz, Anja; Mensink, Gert B. M.
Background The well-being of persons with overweight and obesity, in particular of children and adolescents, may be impaired. The present study investigates the health-related quality of life (HRQoL) of girls and boys ...
2020-10-17Zeitschriftenartikel
Completeness of tuberculosis case notifications in Germany in 2013–2017: first results of an inventory study 
Domaszewska, Teresa; Karo, Basel; Preuss, Ute; Kollan, Christian; Reuss, Annicka; Blank, Hans-Peter; Brodhun, Bonita; Hauer, Barbara; Altmann, Doris; Fiebig, Lena; Haas, Walter; Perumal, Nita
Background Evaluating the completeness of tuberculosis (TB) notification data is important for monitoring of TB surveillance systems. We conducted an inventory study to calculate TB underreporting in Germany in ...
2021-01-27Zeitschriftenartikel
Hematology and Clinical Chemistry Reference Ranges for Laboratory-Bred Natal Multimammate Mice (Mastomys natalensis) 
Wozniak, David M.; Kirchoff, Norman; Hansen-Kant, Katharina; Sogoba, Nafomon; Safronetz, David; Prescott, Joseph
Laboratory-controlled physiological data for the multimammate rat (Mastomys natalensis) are scarce, despite this species being a known reservoir and vector for zoonotic viruses, including the highly pathogenic Lassa virus, ...
2021-01-15Zeitschriftenartikel
Cryptococcus bacillisporus (VGIII) Meningoencephalitis Acquired in Santa Cruz, Bolivia 
Thompson, Luis; Porte, Lorena; Díaz, Violeta; Díaz, María Cristina; Solar, Sebastián; Valenzuela, Pablo; Norley, Nicole; Pires, Yumai; Carreño, Fernando; Valenzuela, Sergio; Shabani, Rukmane; Rickerts, Volker; Weitzel, Thomas
We describe a case of chronic meningoencephalitis with hydrocephalus caused by Crypto- coccus bacillisporus (VGIII) in an immunocompetent patient from Santa Cruz, Bolivia. This first report of a member of the Cryptococcus ...
2021-01-29Zeitschriftenartikel
Utility of a Sequence-Independent, Single-Primer-Amplification (SISPA) and Nanopore Sequencing Approach for Detection and Characterization of Tick-Borne Viral Pathogens 
Brinkmann, Annik; Uddin, Steven; Krause, Eva; Surtees, Rebecca; Dinçer, Ender; Kar, Sırrı; Hacıoğlu, Sabri; Özkul, Aykut; Ergünay, Koray; Nitsche, Andreas
Currently, next generation sequencing (NGS) is the mainly used approach for identification and monitorization of viruses with a potential public health threat in clinical and environmental samples. To facilitate detection ...
2021-03-02Zeitschriftenartikel
Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase (pks) Island 
Suresh, Arya; Shaik, Sabiha; Baddam, Ramani; Ranjan, Amit; Qumar, Shamsul; Jadhav, Savita; Semmler, Torsten; Ghazi, Irfan A.; Wieler, Lothar H.; Ahmed, Niyaz
The genotoxin colibactin is a secondary metabolite produced by the polyketide synthase (pks) island harbored by extraintestinal pathogenic E. coli (ExPEC) and other members of the Enterobacteriaceae that has been increasingly ...
2021-02-20Zeitschriftenartikel
First Description of a Temperate Bacteriophage (vB_FhiM_KIRK) of Francisella hispaniensis Strain 3523 
Köppen, Kristin; Prensa, Grisna I.; Rydzewski, Kerstin; Tlapák, Hana; Holland, Gudrun; Heuner, Klaus
Here we present the characterization of a Francisella bacteriophage (vB_FhiM_KIRK) including the morphology, the genome sequence and the induction of the prophage. The prophage sequence (FhaGI-1) has previously been ...
2021-03-22Zeitschriftenartikel
Are depressive symptoms associated with quality of care in diabetes? Findings from a nationwide populationbased study 
Jung, Andreas; Du, Yong; Nübel, Julia; Busch, Markus A.; Heidemann, Christin; Scheidt-Nave, Christa; Baumert, Jens
Introduction We investigated whether the presence of depressive symptoms among adults with diagnosed diabetes is associated with adverse quality of diabetes care. Research design and methods The study population was ...
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