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2022-06-05Zeitschriftenartikel
Seroprevalence of Measles-, Mumps-, and Rubella-specific antibodies in the German adult population – cross-sectional analysis of the German Health Interview and Examination Survey for Adults (DEGS1) 
Friedrich, Nicole; Poethko-Muller, Christina; Kuhnert, Ronny; Matysiak-Klose, Dorothea; Koch, Judith; Wichmann, Ole; Santibanez, Sabine; Mankertz, Annette
Background: The WHO European Region targets the elimination of measles, rubella, and the congenital rubella syndrome and welcomes mumps elimination via the joint MMR vaccine. In a push towards this elimination goal, Germany ...
2022-01-14Zeitschriftenartikel
COVID-19 infections in day care centres in Germany: social and organisational determinants of infections in children and staff in the second and third wave of the pandemic 
Neuberger, Franz; Grgic, Mariana; Diefenbacher, Svenja; Spensberger, Florian; Lehfeld, Ann-Sophie; Buchholz, Udo; Haas, Walter; Kalicki, Bernhard; Kuger, Susanne
Background: During the SARS-CoV-2 pandemic, German early childhood education and care (ECEC) centres organised children’s attendance in different ways, they reduced opening hours, provided emergency support for a few ...
2022-01-19Zeitschriftenartikel
Lateral flow–based nucleic acid detection of SARS-CoV-2 using enzymatic incorporation of biotin-labeled dUTP for POCT use 
Agarwal, Saloni; Warmt, Christian; Henkel, Joerg; Schrick, Livia; Nitsche, Andreas; Bier, Frank F.
The degree of detrimental effects inflicted on mankind by the COVID-19 pandemic increased the need to develop ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free, and Deliverable) POCT ...
2021-12-16Zeitschriftenartikel
Context-aware genomic surveillance reveals hidden transmission of a carbapenemase-producing Klebsiella pneumoniae 
Viehweger, Adrian; Blumenscheit, Christian; Lippmann, Norman; Wyres, Kelly L.; Brandt, Christian; Hans, Jörg B.; Hölzer, Martin; Irber, Luiz; Gatermann, Sören; Lübbert, Christoph; Pletz, Mathias W.; Holt, Kathryn E.; König, Brigitte
Genomic surveillance can inform effective public health responses to pathogen outbreaks. However, integration of non-local data is rarely done. We investigate two large hospital outbreaks of a carbapenemase-carrying ...
2022-01-04Zeitschriftenartikel
Investigation of a Limited but Explosive COVID-19 Outbreak in a German Secondary School 
Baumgarte, Sigrid; Hartkopf, Felix; Hölzer, Martin; von Kleist, Max; Neitz, Sabine; Kriegel, Martin; Bollongino, Kirsten
The role of schools as a source of infection and driver in the coronavirus-pandemic has been controversial and is still not completely clarified. To prevent harm and disadvantages for children and adolescents, but also ...
2022-01-14Zeitschriftenartikel
SARS-CoV-2 outbreaks in hospitals and long-term care facilities in Germany: a national observational study 
Suwono, Beneditta; Steffen, Annika; Schweickert, Birgitta; Schonfeld, Viktoria; Brandl, Michael; Sandfort, Mirco; Willrich, Niklas; Eckmanns, Tim; Haller, Sebastian
Background: Outbreaks of coronavirus disease (COVID-19) in hospitals and long-term care facilities (LTCFs) pose serious public health threats. We analysed how frequency and size of SARS-CoV-2 outbreaks in hospitals and ...
2022-03-11Zeitschriftenartikel
Identification of Mucormycosis by Fluorescence In Situ Hybridization Targeting Ribosomal RNA in Tissue Samples 
Dalimot, Jill Jasmine; Smith, Ilka Mc Cormick; Gerkrath, Jasmin; Hartmann, Sylvia; Cornely, Oliver A.; Lee, Soo Chan; Heitman, Joseph; Rickerts, Volker
Mucormycosis is an invasive fungal infection associated with high mortality, partly due to delayed diagnosis and inadequate empiric therapy. As fungal cultures often fail to grow Mucorales, identification of respective ...
2022-02-02Zeitschriftenartikel
Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance 
Gömer, André; Brown, Richard J. P.; Pfaender, Stephanie; Deterding, Katja; Reuter, Gábor; Orton, Richard; Seitz, Stefan; Bock, C.- Thomas; Cavalleri, Jessika M. V.; Pietschmann, Thomas; Wedemeyer, Heiner; Steinmann, Eike; Todt, Daniel
Even 30 years after the discovery of the hepatitis C virus (HCV) in humans there is still no vaccine available. Reasons for this include the high mutation rate of HCV, which allows the virus to escape immune recognition ...
2022-03-21Zeitschriftenartikel
Cluster of human Puumala orthohantavirus infections due to indoor exposure?—An interdisciplinary outbreak investigation 
Princk, Christina; Drewes, Stephan; Meyer-Schlinkmann, Kristin M.; Saathoff, Marion; Binder, Florian; Freise, Jona; Tenner, Beate; Weiss, Sabrina; Hofmann, Jörg; Esser, Jutta; Runge, Martin; Jacob, Jens; Ulrich, Rainer G.; Dreesman, Johannes
Puumala orthohantavirus (PUUV) is the most important hantavirus species in Europe, causing the majority of human hantavirus disease cases. In central and western Europe, the occurrence of human infections is mainly driven ...
2022-03-23Zeitschriftenartikel
Tick-Borne Encephalitis Risk Increases with Dog Ownership, Frequent Walks, and Gardening: A Case-Control Study in Germany 2018–2020 
Nygren, Teresa Marie; Pilic, Antonia; Böhmer, Merle Margarete; Wagner-Wiening, Christiane; Wichmann, Ole; Harder, Thomas; Hellenbrand, Wiebke
In Germany, tick-borne encephalitis (TBE) infections mainly occur in southern regions. Despite recent increases in incidence, TBE vaccination coverage remains low, necessitating additional preventive strategies against ...
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