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2023-02-16Zeitschriftenartikel
Comparative effectiveness of contact tracing interventions in the context of the COVID-19 pandemic: a systematic review 
Pozo-Martin, Francisco; Beltran Sanchez, Miguel Angel; Müller, Sophie Alice; Diaconu, Viorela; Weil, Kilian; El Bcheraoui, Charbel
Contact tracing is a non-pharmaceutical intervention (NPI) widely used in the control of the COVID-19 pandemic. Its effectiveness may depend on a number of factors including the proportion of contacts traced, delays in ...
2023-01-24Zeitschriftenartikel
Dot Immunobinding Assay for the Rapid Serodetection of Scedosporium/Lomentospora in Cystic Fibrosis Patients 
Martin-Souto, Leire; Antoran, Aitziber; Areitio, Maialen; Aparicio-Fernandez, Leire; Martín-Gómez, María Teresa; Fernandez, Roberto; Astigarraga, Egoitz; Barreda-Gómez, Gabriel; Schwarz, Carsten; Rickerts, Volker; Hernando, Fernando L.; Rementeria, Aitor; Buldain, Idoia; Ramirez-Garcia, Andoni
The detection of Scedosporium/Lomentospora is still based on non-standardized low-sensitivity culture procedures. This fact is particularly worrying in patients with cystic fibrosis (CF), where these fungi are the second ...
2023-04-02Zeitschriftenartikel
Monitoring the SARS-CoV-2 Pandemic: Prevalence of Antibodies in a Large, Repetitive Cross-Sectional Study of Blood Donors in Germany—Results from the SeBluCo Study 2020–2022 
Offergeld, Ruth; Preußel, Karina; Zeiler, Thomas; Aurich, Konstanze; Baumann-Baretti, Barbara I.; Ciesek, Sandra; Corman, Victor M.; Dienst, Viktoria; Drosten, Christian; Görg, Siegfried; Greinacher, Andreas; Grossegesse, Marica; Haller, Sebastian; Heuft, Hans-Gert; Hofmann, Natalie; Horn, Peter A.; Houareau, Claudia; Gülec, Ilay; Jiménez Klingberg, Carlos Luis; Juhl, David; Lindemann, Monika; Martin, Silke; Neuhauser, Hannelore K.; Nitsche, Andreas; Ohme, Julia; Peine, Sven; Sachs, Ulrich J.; Schaade, Lars; Schäfer, Richard; Scheiblauer, Heinrich; Schlaud, Martin; Schmidt, Michael; Umhau, Markus; Vollmer, Tanja; Wagner, Franz F.; Wieler, Lothar H.; Wilking, Hendrik; Ziemann, Malte; Zimmermann, Marlow; an der Heiden, Matthias
SARS-CoV-2 serosurveillance is important to adapt infection control measures and estimate the degree of underreporting. Blood donor samples can be used as a proxy for the healthy adult population. In a repeated cross-sectional ...
2023-02-10Zeitschriftenartikel
Disease severity in hospitalized COVID-19 patients: comparing routine surveillance with cohort data from the LEOSS study in 2020 in Germany 
Koppe, Uwe; Schilling, Julia; Stecher, Melanie; Rüthrich, Maria Madeleine; Marquis, Adine; Diercke, Michaela; Haselberger, Martina; Koll, Carolin E. M.; Niebank, Michaela; Ruehe, Bettina; Borgmann, Stefan; Grabenhenrich, Linus; Hellwig, Kerstin; Pilgram, Lisa; Spinner, Christoph D.; Paerisch, Thomas
Introduction Studies investigating risk factors for severe COVID-19 often lack information on the representativeness of the study population. Here, we investigate factors associated with severe COVID-19 and compare the ...
2022-12-21Zeitschriftenartikel
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia 
Saghuag, Christina S.; Gamlem, Astrid L.; Hauge, Kirsti B.; Vahokoski, Juha; Klotz, Christian; Langeland, Nina; Hanevik, Kurt; Aebischer, Toni
The effectiveness of metronidazole against the tetraploid intestinal parasite Giardia lamblia is dependent on its activation/inactivation within the cytoplasm. There are several activating enzymes, including pyruvate ...
2023-02-10Zeitschriftenartikel
Self-rated health of university students in Germany–The importance of material, psychosocial, and behavioral factors and the parental socio-economic status 
Deindl, Christian; Diehl, Katharina; Spalleck, Jacob; Richter, Matthias; Schüttig, Wiebke; Rattay, Petra; Dragano, Nico; Pischke, Claudia R.
Introduction: Health inequalities start early in life. The time of young adulthood, between late teens and early twenties, is especially interesting in this regard. This time of emerging adulthood, the transition from being ...
2021-07-02Zeitschriftenartikel
The increasing significance of disease severity in a burden of disease framework 
Wyper, Grant M. A.; Assuncao, Ricardo; Fletcher, Eilidh; Gourley, Michelle; Grant, Ian; Haagsma, Juanita A.; Hilderink, Henk; Idavain, Jane; Lesnik, Tina; von der Lippe, Elena; Majdan, Marek; Mccartney, Gerry; Santric-Milicevic, Milena; Pallari, Elena; Pires, Sara M.; Plass, Dietrich; Porst, Michael; Santos, João V.; de Haro Moro, Maria Teresa; Stockton, Diane L.; Devleesschauwer, Brecht
Recent estimates have reiterated that non-fatal causes of disease, such as low back pain, headaches and depressive disorders, are amongst the leading causes of disability-adjusted life years (DALYs). For these causes, the ...
2023-02-21Zeitschriftenartikel
Gesundheitliche Chancengleichheit in Krisenzeiten 
Saß, Anke-Christine
2023-01-11Zeitschriftenartikel
Comparison of a Genotype 1 and a Genotype 2 Macaque Foamy Virus env Gene Indicates Distinct Infectivity and Cell-Cell Fusion but Similar Tropism and Restriction of Cell Entry by Interferon-Induced Transmembrane Proteins 
Fricke, Thomas; Schlagowski, Sarah; Liu, Shanchuan; Yang, Xiaoling; Fiebig, Uwe; Kaul, Artur; Ensser, Armin; Hahn, Alexander S.
Foamy viruses (FVs) are naturally found in many different animals and also in primates with the notable exception of humans, but zoonotic infections are common. In several species, two different envelope (env) gene ...
2023-02-25Rezension
Anakinra for the treatment of COVID-19 patients: a systematic review and meta-analysis 
Dahms, Karolina; Mikolajewska, Agata; Ansems, Kelly; Metzendorf, Maria-Inti; Benstoem, Carina; Stegemann, Miriam
Background At the end of 2021, the European Medicines Agency (EMA) expanded its approval for the recombinant human interleukin‑1 (IL‑1) receptor antagonist Anakinra for the treatment of COVID‑19 patients with elevated ...
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