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2020-05-28Zeitschriftenartikel

Survival of Brucella abortus S19 and other Brucella spp. in the presence of oxidative stress and within macrophages

Jacob, Jens; Finke, Antje; Mielke, Martin

The evolutionary “success” of the genus Brucella depends on the ability to persist both in the environment as well as inside of even activated macrophages of the animal host. For that, the Brucellae produce catalase and ...

2020-09-24Zeitschriftenartikel

Häufigkeiten von Patienten mit HIV in der ambulanten Versorgung in Deutschland – Eine Analyse auf Basis von Sekundärdaten

Kurch-Bek, Diana; Gallowitz, Christian; Baumgarten, Axel; Tenckhoff, Bernhard; an der Heiden, Matthias

Hintergrund Jährlich veröffentlicht das Robert Koch-Institut (RKI) die Zahl der HIV-Erstdiagnosen und die Gesamtzahl von Menschen mit HIV-Diagnosen in Deutschland. Eine Bestimmung mithilfe von Sekundärdaten erfolgte ...

2020-04-13Zeitschriftenartikel

Infectious KoRV-related retroviruses circulating in Australian bats

Hayward, Joshua A.; Tachedijan, Mary; Kohl, Claudia; Johnson, Adam; Dearnley, Megan; Jesaveluk, Brianna; Langer, Christine; Solymosi, Philip D.; Hille, Georg; Nitsche, Andreas; Sánchez, Cecilia A.; Werner, Adam; Kontos, Dimitri; Crameri, Gary; Marsh, Glenn A.; Poumbourios, Pantelis; Drummer, Heidi E.; Holmes, Edward C.; Wang, Lin-Fa; Tachedijan, Gilda

Bats are reservoirs of emerging viruses that are highly pathogenic to other mammals, including humans. Despite the diversity and abundance of bat viruses, to date they have not been shown to harbor exogenous retroviruses. ...

2020-09-08Zeitschriftenartikel

Wie viele Personen lassen sich in Deutschland im niedergelassenen Bereich auf HIV testen?

Hofmann, Alexandra; Bätzing, Jörg; Marcus, Ulrich; Bremer, Viviane; Bartmeyer, Barbara

Hintergrund Die Anzahl der in Deutschland auf HIV getesteten Personen ist schwer zu ermitteln. Unter bestimmten Voraussetzungen sind HIV-Tests Leistung der gesetzlichen Krankenversicherung (GKV). Ziel dieser Analyse war ...

2020-09-23Zeitschriftenartikel

A clinician's perspective on yellow fever vaccine-associated neurotropic disease

Lecomte, Elien; Laureys, Guy; Verbeke, Frederick; Domingo Carrasco, Cristina; Van Esbroeck, Marjan; Huits, Ralph

Yellow fever (YF) causes high fever, liver dysfunction, renal failure, hypercoagulopathy and platelet dysfunction and can lead to shock and death with a case-fatality ratio of 20–50%. YF vaccination results in long-lasting ...

2020-10-02Zeitschriftenartikel

Das IMIRA-Projekt am Robert Koch-Institut

The IMIRA project at the Robert Koch Institute

Koschollek, Carmen; Kajikhina, Katja; Bug, Marleen; Santos-Hövener, Claudia

Deutschland ist ein Einwanderungsland und 2019 hatte mehr als jede vierte hier lebende Person einen sog. Migrationshintergrund. Bei dieser statistisch definierten Gruppe handelt es sich um einen heterogenen Personenkreis; ...

2017-11-06Zeitschriftenartikel

Evidence for Human Streptococcus pneumoniae in wild and captive chimpanzees: A potential threat to wild populations

Köndgen, Sophie; Calvignac-Spencer, Sebastien; Grützmacher, Kim; Keil, Verena; Mätz-Rensing, Kerstin; Nowak, Kathrin; Metzger, Sonja; Kiyang, John; Lübke-Becker, Antina; Deschner, Tobias; Wittig, Roman M.; Lankester, Felix; Leendertz, Fabian H.

Habituation of wild great apes for tourism and research has had a significant positive effect on the conservation of these species. However, risks associated with such activities have been identified, specifically the ...

2019-06-25Zeitschriftenartikel

Generalization of the small-world effect on a model approaching the Erdős–Rényi random graph

Maier, Benjamin F.

The famous Watts–Strogatz (WS) small-world network model does not approach the Erdős–Rényi (ER) random graph model in the limit of total randomization which can lead to confusion and complicates certain analyses. In this ...

2020-08-28Zeitschriftenartikel

Selective flexible packaging pathways of the segmented genome of influenza A virus

Haralampiev, Ivan; Prisner, Simon; Nitzan, Mor; Schade, Matthias; Jolmes, Fabian; Schreiber, Max; Loidolt-Krüger, Maria; Jongen, Kalle; Chamiolo, Jasmine; Nilson, Niklaas; Winter, Franziska; Friedman, Nir; Seitz, Oliver; Wolff, Thorsten; Herrmann, Andreas

The genome of influenza A viruses (IAV) is encoded in eight distinct viral ribonucleoproteins (vRNPs) that consist of negative sense viral RNA (vRNA) covered by the IAV nucleoprotein. Previous studies strongly support a ...

2020-05-27Zeitschriftenartikel

A Recent Human Immunodeficiency Virus Outbreak Among People Who Inject Drugs in Munich, Germany, Is Associated With Consumption of Synthetic Cathinones

Hanke, Kirsten; Fiedler, Stefan; Grumann, Christina; Ratmann, Oliver; Hauser, Andrea; Klink, Patrycja; Meixenberger, Karolin; Altmann, Britta; Zimmermann, Ruth; Marcus, Ulrich; Bremer, Viviane; Auwärter, Volker; Bannert, Norbert

Background. Needle and syringe sharing among people who inject drugs (PWID) can result in a rapid regional spread of a human immunodeficiency virus (HIV) variant. Such outbreaks have been identified recently in several ...

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