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Now showing items 791-800 of 3394

2017-05-01Zeitschriftenartikel

Ebola management centre proximity associated with reduced delays of healthcare of Ebola Virus Disease (EVD) patients, Tonkolili, Sierra Leone, 2014–15

Theocharopoulos, Georgios; Danis, Kostas; Greig, Jane; Hoffmann, Alexandra; Valk, Henriette De; Jimissa, Augustine; Tejan, Sumaila; Sankoh, Mohammed; Kleijer, Karline; Turner, Will; Achar, Jay; Duncombe, Jennifer; Lokuge, Kamalini; Gayton, Ivan; Broeder, Rob; Kremer, Ronald; Caleo, Grazia

Between August-December 2014, Ebola Virus Disease (EVD) patients from Tonkolili District were referred for care to two Médecins Sans Frontières (MSF) Ebola Management Centres (EMCs) outside the district (distant EMCs). In ...

2017-05-22Zeitschriftenartikel

Parvovirus B19-induced vascular damage in the heart is associated with elevated circulating endothelial microparticles

Bachelier, Katrin; Biehl, Susanne; Schwarz, Viktoria; Kindermann, Ingrid; Kandolf, Reinhard; Sauter, Martina; Ukena, Christian; Yilmaz, Ali; Sliwa, Karen; Bock, Thomas; Klingel, Karin; Böhm, Michael

Background: Diagnosis of viral myocarditis is difficult by clinical criteria but facilitated by detection of inflammation and viral genomes in endomyocardial biopsies. Parvovirus B19 (B19V) targets endothelial cells ...

2017-05-18Zeitschriftenartikel

Why are some people more fit than others? Correlates and determinants of cardiorespiratory fitness in adults: protocol for a systematic review

Perumal, Nita; Mensink, Gert; Keil, Thomas; Finger, Jonas

Background: Cardiorespiratory fitness (CRF) is a physical condition that is now well established as a predictor of numerous adverse health outcomes, independent of physical activity levels. In order to be able to improve ...

2017-05-18Zeitschriftenartikel

Temporal dynamics of online petitions

Böttcher, Lucas; Woolley-Meza, Olivia; Brockmann, Dirk

Online petitions are an important avenue for direct political action, yet the dynamics that determine when a petition will be successful are not well understood. Here we analyze the temporal characteristics of online-petition ...

2017-03-14Zeitschriftenartikel

Wild African great apes as natural hosts of malaria parasites: current knowledge and research perspectives

Nys, Hélène Marie De; Löhrich, Therese; Wu, Doris; Calvignac-Spencer, Sébastien; Leendertz, Fabian H.

Humans and African great apes (AGAs) are naturally infected with several species of closely related malaria parasites. The need to understand the origins of human malaria as well as the risk of zoonotic transmissions and ...

2017-03-27Zeitschriftenartikel

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection

Semini, Geo; Paape, Daniel; Paterou, Athina; Schroeder, Juliane; Barrios-Llerena, Martin; Aebischer, Toni

Leishmania spp. are protozoan parasites that are transmitted by sandfly vectors during blood sucking to vertebrate hosts and cause a spectrum of diseases called leishmaniases. It has been demonstrated that host cholesterol ...

2017-04-11Zeitschriftenartikel

Is the impact of childhood influenza vaccination less than expected: a transmission modelling study

Weidemann, Felix; Remschmidt, Cornelius; Buda, Silke; Buchholz, Udo; Ultsch, Bernhard; Wichmann, Ole

Background: To reduce the burden of severe influenza, most industrialized countries target specific risk-groups with influenza vaccines, e.g. the elderly or individuals with comorbidities. Since children are the main ...

2017-03-28Zeitschriftenartikel

SLIMM: species level identification of microorganisms from metagenomes

Dadi, Temesgen Hailemariam; Renard, Bernhard Y.; Wieler, Lothar H.; Semmler, Torsten; Reinert, Knut

Identification and quantification of microorganisms is a significant step in studying the alpha and beta diversities within and between microbial communities respectively. Both identification and quantification of a given ...

2016-08-28Zeitschriftenartikel

Phylogenetic structure of European Salmonella Enteritidis outbreak correlates with national and international egg distribution network

Dallman, Tim; Inns, Thomas; Jombart, Thibaut; Ashton, Philip; Loman, Nicolas; Chatt, Carol; Messelhaeusser, Ute; Rabsch, Wolfgang; Simon, Sandra; Nikisins, Sergejs; Bernard, Helen; Hello, Simon le; da-Silva, Nathalie Jourdan; Kornschober, Christian; Mossong, Joel; Hawkey, Peter; Pinna, Elizabeth de; Grant, Kathie; Cleary, Paul

Outbreaks of Salmonella Enteritidis have long been associated with contaminated poultry and eggs. In the summer of 2014 a large multi-national outbreak of Salmonella Enteritidis phage type 14b occurred with over 350 cases ...

2017-03-21Zeitschriftenartikel

Nursing staff fluctuation and pathogenic burden in the NICU - effective outbreak management and the underestimated relevance of non-resistant strains

Hensel, Kai O.; Bruck, Rhea van den; Klare, Ingo; Heldmann, Michael; Ghebremedhin, Beniam; Jenke, Andreas C.

In the course of a hospital management takeover, a microbial outbreak took place in a tertiary neonatal intensive care unit (NICU). Here, we characterize the outbreak and its management. About 4 months prior to takeover, ...

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