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2018-10-08Zeitschriftenartikel DOI: 10.25646/5903
Incidence of notified Lyme borreliosis in Germany, 2013–2017
dc.contributor.authorEnkelmann, Julia
dc.contributor.authorBöhmer, Merle
dc.contributor.authorFingerle, Volker
dc.contributor.authorSiffczyk, Claudia
dc.contributor.authorWerber, Dirk
dc.contributor.authorLittmann, Martina
dc.contributor.authorMerbecks, Sophie-Susann
dc.contributor.authorHelmeke, Carina
dc.contributor.authorSchroeder, Sabine
dc.contributor.authorHell, Stefan
dc.contributor.authorSchlotthauer, Uwe
dc.contributor.authorBurckhardt, Florian
dc.contributor.authorStark, Klaus
dc.contributor.authorSchielke, Anika
dc.contributor.authorWilking, Hendrik
dc.date.accessioned2019-02-20T13:01:13Z
dc.date.available2019-02-20T13:01:13Z
dc.date.issued2018-10-08none
dc.identifier.other10.1038/s41598-018-33136-0
dc.identifier.urihttp://edoc.rki.de/176904/5943
dc.description.abstractLyme borreliosis (LB) is the most commonly reported tick-borne disease in Germany. In 9/16 states, notification of erythema migrans (EM), acute neuroborreliosis (NB) and Lyme arthritis (LA) is mandatory. We describe incidence measures, time trends, geographical distribution and frequencies of manifestations to better understand LB epidemiology and target prevention measures. We used cases notified in the 9 states and confirmed by local health offices, 2013–2017, to calculate incidences by time, place and person. Altogether, we observed 56,446 cases. Disease onset peaked yearly in July. Incidence ranged from 26/100,000 (2015) to 41/100,000 (2013) with mean annual incidences 2013–2017 on district level between 0.5/100,000 and 138/100,000. Median age was 54 years with peaks in boys (5–9 years, mean incidence 36/100,000) and women (50–69 years, mean incidence 57/100,000). 95% experienced EM only, 2.7% NB and 2.1% LA. 54% were female, but more men had NB (56%) and LA (53%, p < 0.001). Hospitalisation was recorded for 10% of LA and 71% of NB cases. LB remains an important public health concern in Germany with marked regional variation. To facilitate early diagnosis and treatment, health authorities should raise awareness among physicians and promote prevention strategies among the general population: tick-bite-protection, prompt tick removal and medical consultation.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleIncidence of notified Lyme borreliosis in Germany, 2013–2017none
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/5943-9
dc.identifier.doihttp://dx.doi.org/10.25646/5903
dc.type.versionpublishedVersionnone
local.edoc.container-titleScientific Reportsnone
local.edoc.pages8none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.nature.com/articles/s41598-018-33136-0#article-infonone
local.edoc.container-publisher-nameNature Publishing Groupnone
local.edoc.container-volume8none
local.edoc.container-issue14976none
local.edoc.container-reportyear2018none
local.edoc.container-year2018none
local.edoc.container-firstpage1none
local.edoc.container-lastpage8none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

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