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2019-02-22Zeitschriftenartikel DOI: 10.25646/5951
Detection of PCV3 in German wild boars
dc.contributor.authorPrinz, Carolin
dc.contributor.authorStillfried, Milena
dc.contributor.authorNeubert, Lena Katharina
dc.contributor.authorDenner, Joachim
dc.date.accessioned2019-03-14T12:00:41Z
dc.date.available2019-03-14T12:00:41Z
dc.date.issued2019-02-22none
dc.identifier.other10.1186/s12985-019-1133-9
dc.identifier.urihttp://edoc.rki.de/176904/5986
dc.description.abstractBackground Porcine circovirus 3 is a newly described circovirus circulating worldwide. PCV3 may play an etiologic role in different pig diseases. Two different genotypes of PCV3 were described, PCV3a and PCV3b. In order to analyse whether PCV3 is also present in wild boars, animals living in and near Berlin were studied. The animals had been analysed previously and were found to form two genetically distinct and geographically coherent clusters. Methods To detect PCV3 in wild boars, a PCR was performed, to analyse the virus in detail, parts of the sequence of the capsid protein were sequenced. In addition, a screening for PCV1 and PCV2 was performed using PCR. Results For the first time, PCV3 was detected in German wild boars, with 50% of the animals infected in one genetic cluster, and 23% in the second cluster. In both populations which were divided in the years of division of Berlin, PCV3b was detected, in one case also PCV3a was detected. In some animals, co-infections with PCV1 and PCV2 or triple infections were detected. Conclusion The data show a high prevalence of PCV3 and co-infections with PCV1 and PCV2 in German wild boars. The finding of PCV3 in both clusters suggests that the virus was introduced into the animal populations before Berlin was divided. Furthermore, the methods used will be indispensable for screening for circoviruses in pigs genetically modified for xenotransplantation.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectPorcine circoviruseseng
dc.subjectPCV3eng
dc.subjectWild boarseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleDetection of PCV3 in German wild boarsnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/5986-9
dc.identifier.doihttp://dx.doi.org/10.25646/5951
dc.type.versionpublishedVersionnone
local.edoc.container-titleVirology Journalnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://virologyj.biomedcentral.com/articles/10.1186/s12985-019-1133-9none
local.edoc.container-publisher-nameBioMed Centralnone
local.edoc.container-volume16none
local.edoc.container-issue25none
local.edoc.container-reportyear2019none
local.edoc.container-year2019none
local.edoc.container-firstpage1none
local.edoc.container-lastpage7none
local.edoc.rki-departmentInfektionskrankheitennone
dc.description.versionPeer Reviewednone

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