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2018-01-17Zeitschriftenartikel DOI: 10.25646/6049
Environmental adaptation and vertical dissemination of ESBL‐/pAmpC‐producing Escherichia coli in an integrated broiler production chain in the absence of an antibiotic treatment
dc.contributor.authorProjahn, Michaela
dc.contributor.authorDaehre, Katrin
dc.contributor.authorSemmler, Torsten
dc.contributor.authorGuenther, Sebastian
dc.contributor.authorRoesler, Uwe
dc.contributor.authorFriese, Anika
dc.date.accessioned2019-04-05T07:59:38Z
dc.date.available2019-04-05T07:59:38Z
dc.date.issued2018-01-17none
dc.identifier.other10.1111/1751-7915.13040
dc.identifier.urihttp://edoc.rki.de/176904/6084
dc.description.abstractHigh prevalence numbers of extended-spectrum beta-lactamase- (ESBL-)/plasmid-mediated AmpC beta-lactamase- (pAmpC-) producing Escherichia coli in broiler chicken and their distribution along the broiler production chain is an ongoing problem in food production. We, therefore, investigated resistant isolates along the broiler production chain to determine whether there is a constantly occurring direct vertical transmission of the ESBL-/pAmpC-producing E. coli from the parent flocks to their offspring or not. We, furthermore, analysed the isolates concerning the occurrence of virulence factors and their ability to form biofilms to estimate their potential to effectively colonize broiler chickens and/or persist and survive in the environment of the broiler production facilities. Using whole genome sequencing, we could show that ESBL-/pAmpC-producing E. coli were likely transferred in a step-wise process along the broiler production chain but not directly from the parent flock to the fattening flock with every single batch of offspring chickens. Additionally, resistant E. coli strains showing an extraintestinal pathogenic genotype as well as high numbers of virulence-associated genes including the production of curli fibres and cellulose have high capabilities to persist and spread in the broiler production chain.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleEnvironmental adaptation and vertical dissemination of ESBL‐/pAmpC‐producing Escherichia coli in an integrated broiler production chain in the absence of an antibiotic treatmentnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/6084-8
dc.identifier.doihttp://dx.doi.org/10.25646/6049
dc.type.versionpublishedVersionnone
local.edoc.container-titleMicrobial Biotechnologynone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://onlinelibrary.wiley.com/doi/full/10.1111/1751-7915.13040none
local.edoc.container-publisher-nameWiley-Blackwellnone
local.edoc.container-volume11none
local.edoc.container-issue6none
local.edoc.container-reportyear2018none
local.edoc.container-year2018none
local.edoc.container-firstpage1017none
local.edoc.container-lastpage1026none
local.edoc.rki-departmentProjektgruppen/Nachwuchsgruppennone
dc.description.versionPeer Reviewednone

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