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2020-01-10Zeitschriftenartikel DOI: 10.25646/6608
High prevalence of hepatitis C virus infection and low level of awareness among people who recently started injecting drugs in a cross-sectional study in Germany, 2011–2014: missed opportunities for hepatitis C testing
dc.contributor.authorEnkelmann, Julia
dc.contributor.authorGassowski, Martyna
dc.contributor.authorNielsen, Stine
dc.contributor.authorWenz, Benjamin
dc.contributor.authorRoß, Stefan
dc.contributor.authorMarcus, Ulrich
dc.contributor.authorBremer, Viviane
dc.contributor.authorZimmermann, Ruth
dc.contributor.authorDRUCK Study group
dc.date.accessioned2020-03-26T10:58:39Z
dc.date.available2020-03-26T10:58:39Z
dc.date.issued2020-01-10none
dc.identifier.other10.1186/s12954-019-0338-y
dc.identifier.urihttp://edoc.rki.de/176904/6566
dc.description.abstractBackground In Germany, risk of hepatitis C virus (HCV) infection is highest among people who inject drugs (PWID). New injectors (NI) are particularly vulnerable for HCV-acquisition, but little is known about health seeking behaviour and opportunities for intervention in this group. We describe characteristics, HCV prevalence, estimated HCV incidence and awareness of HCV-status among NIs and missed opportunities for hepatitis C testing. Methods People who had injected drugs in the last 12 months were recruited into a cross-sectional serobehavioural study using respondent-driven sampling in 8 German cities, 2011–2014. Data on sociodemographic characteristics, previous HCV testing and access to care were collected through questionnaire-based interviews. Capillary blood was tested for HCV. People injecting drugs < 5 years were considered NI. Results Of 2059 participants with available information on duration of injection drug use, 232 (11% were NI. Estimated HCV incidence among NI was 19.6 infections/100 person years at risk (95% CI 16–24). Thirty-six percent of NI were HCV-positive (thereof 76% with detectable RNA) and 41% of those HCV-positive were unaware of their HCV-status. Overall, 27% of NI reported never having been HCV-tested. Of NI with available information, more than 80% had attended low-threshold drug services in the last 30 days, 24% were released from prison in the last 12 months and medical care was most commonly accessed in hospitals, opioid substitution therapy (OST)-practices, practices without OST and prison hospitals. Conclusion We found high HCV-positivity and low HCV-status awareness among NI, often with missed opportunities for HCV-testing. To increase early diagnosis and facilitate treatment, HCV-testing should be offered in all facilities, where NI can be reached, especially low-threshold drug services and addiction therapy, but also prisons, hospitals and practices without OST.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectHCVeng
dc.subjectPWIDeng
dc.subjectNew injectorseng
dc.subjectHepatitis C testingeng
dc.subjectGermanyeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleHigh prevalence of hepatitis C virus infection and low level of awareness among people who recently started injecting drugs in a cross-sectional study in Germany, 2011–2014: missed opportunities for hepatitis C testingnone
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/6566-5
dc.identifier.doihttp://dx.doi.org/10.25646/6608
dc.type.versionpublishedVersionnone
local.edoc.container-titleHarm Reduction Journalnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://harmreductionjournal.biomedcentral.com/articles/10.1186/s12954-019-0338-y#Sec3none
local.edoc.container-publisher-nameBioMed Centralnone
local.edoc.container-volume17none
local.edoc.container-issue7none
local.edoc.container-year2020none
local.edoc.container-firstpage1none
local.edoc.container-lastpage10none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

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