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2019-02-18Zeitschriftenartikel DOI: 10.25646/6612
European all-cause excess and influenza-attributable mortality in the 2017/18 season: should the burden of influenza B be reconsidered?
dc.contributor.authorNielsen, J.
dc.contributor.authorVestergaard, L. S.
dc.contributor.authorRichter, L.
dc.contributor.authorSchmid, D.
dc.contributor.authorBustos, N.
dc.contributor.authorAsikainen, T.
dc.contributor.authorTrebbien, B.
dc.contributor.authorDenissov, G.
dc.contributor.authorInnos, K.
dc.contributor.authorVirtanen, M. J.
dc.contributor.authorFouillet, A.
dc.contributor.authorLytras, T.
dc.contributor.authorGkolfinopoulou, K.
dc.contributor.authoran der Heiden, Matthias
dc.contributor.authorGrabenhenrich, Linus
dc.contributor.authorUphoff, H.
dc.contributor.authorPaldy, A.
dc.contributor.authorBobvos, J.
dc.contributor.authorDomegan, L.
dc.contributor.authorO'Donnell, J.
dc.contributor.authorScortichini, M.
dc.contributor.authorde Martino, A.
dc.contributor.authorMossong, J.
dc.contributor.authorEngland, K.
dc.contributor.authorMelillo, J.
dc.contributor.authorvan Asten, L.
dc.contributor.authorde Lange, M. MA
dc.contributor.authorTønnessen, R.
dc.contributor.authorWhite, R. A.
dc.contributor.authorda Silva, S. P.
dc.contributor.authorRodrigues, A. P.
dc.contributor.authorLarrauri, A.
dc.contributor.authorMazagatos, C.
dc.contributor.authorFarah, A.
dc.contributor.authorCarnahan, A. D.
dc.contributor.authorJunker, C.
dc.contributor.authorSinnathamby, M.
dc.contributor.authorPebody, R. G.
dc.contributor.authorAndrews, N.
dc.contributor.authorReynolds, A.
dc.contributor.authorMcMenamin, J.
dc.contributor.authorBrown, C. S.
dc.contributor.authorAdlhoch, C.
dc.contributor.authorPenttinen, P.
dc.contributor.authorMølbak, K.
dc.contributor.authorKrause, T.G.
dc.date.accessioned2020-03-27T09:30:51Z
dc.date.available2020-03-27T09:30:51Z
dc.date.issued2019-02-18none
dc.identifier.other10.1016/j.cmi.2019.02.011
dc.identifier.urihttp://edoc.rki.de/176904/6571
dc.description.abstractObjectives Weekly monitoring of European all-cause excess mortality, the EuroMOMO network, observed high excess mortality during the influenza B/Yamagata dominated 2017/18 winter season, especially among elderly. We describe all-cause excess and influenza-attributable mortality during the season 2017/18 in Europe. Methods Based on weekly reporting of mortality from 24 European countries or sub-national regions, representing 60% of the European population excluding the Russian and Turkish parts of Europe, we estimated age stratified all-cause excess morality using the EuroMOMO model. In addition, age stratified all-cause influenza-attributable mortality was estimated using the FluMOMO algorithm, incorporating influenza activity based on clinical and virological surveillance data, and adjusting for extreme temperatures. Results Excess mortality was mainly attributable to influenza activity from December 2017 to April 2018, but also due to exceptionally low temperatures in February-March 2018. The pattern and extent of mortality excess was similar to the previous A(H3N2) dominated seasons, 2014/15 and 2016/17. The 2017/18 overall all-cause influenza-attributable mortality was estimated to be 25.4 (95%CI 25.0-25.8) per 100,000 population; 118.2 (116.4-119.9) for persons aged 65. Extending to the European population this translates into over-all 152,000 deaths. Conclusions The high mortality among elderly was unexpected in an influenza B dominated season, which commonly are considered to cause mild illness, mainly among children. Even though A(H3N2) also circulated in the 2017/18 season and may have contributed to the excess mortality among the elderly, the common perception of influenza B only having a modest impact on excess mortality in the older population may need to be reconsidered.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectB/Yamagataeng
dc.subjectEuroMOMOeng
dc.subjectFluMOMOeng
dc.subjectInfluenzaeng
dc.subjectMortalityeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleEuropean all-cause excess and influenza-attributable mortality in the 2017/18 season: should the burden of influenza B be reconsidered?none
dc.typearticle
dc.identifier.urnurn:nbn:de:kobv:0257-176904/6571-2
dc.identifier.doihttp://dx.doi.org/10.25646/6612
dc.type.versionpublishedVersionnone
local.edoc.container-titleClinical Microbiology and Infectionnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.sciencedirect.com/science/article/pii/S1198743X19300588?via%3Dihubnone
local.edoc.container-publisher-nameElseviernone
local.edoc.container-volume25none
local.edoc.container-issue10none
local.edoc.container-year2019none
local.edoc.container-firstpage1266none
local.edoc.container-lastpage1276none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

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