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2009-06-25Zeitschriftenartikel DOI: 10.1111/j.1600-0447.2009.01435.x
The role of the inflammatory markers ferritin, transferrin and fibrinogen in the relationship between major depression and cardiovascular disorders
dc.contributor.authorBaune, B. T.
dc.contributor.authorNeuhauser, Hannelore
dc.contributor.authorEllert, Ute
dc.contributor.authorBerger, Klaus
dc.date.accessioned2018-05-07T14:01:01Z
dc.date.available2018-05-07T14:01:01Z
dc.date.created2010-06-30
dc.date.issued2009-06-25none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/re9uASHPYf9I/PDF/21NGQ417ehBaU.pdf
dc.identifier.urihttp://edoc.rki.de/176904/685
dc.description.abstractObjective: To determine levels of inflammation (ferritin, transferrin and fibrinogen) in major depression (MDD) and comorbid cardiovascular disease (CVD) in an adult population. Method: In 4181 participants of the German Health Interview and Examination Survey MDD was assessed through the Composite International Diagnostic Interview (CIDI). Coronary heart disease, stroke, and hypertension were diagnosed by a computer-assisted physician interview. Analyses were performed using anova models stratified for gender. Results: Ferritin, transferrin and fibrinogen levels showed opposing patterns in individuals with either CVD or MDD alone. In comorbidity analyses, male participants with MDD plus comorbid CHD or hypertension had lower levels of ferritin and lower fibrinogen levels in hypertension compared to men without MDD, while in women, results were inconsistent. Conclusion: Opposing patterns of inflammatory markers in CVD or MDD alone were reversed when both conditions were present. MDD reduced levels of ferritin, transferrin and fibrinogen in CVD in a gender-specific way.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut
dc.subjectAgedeng
dc.subjectHumanseng
dc.subjectFemaleeng
dc.subjectGermanyeng
dc.subjectMaleeng
dc.subjectQuestionnaireseng
dc.subjectInterviews as Topiceng
dc.subjectHealth Statuseng
dc.subjectSocial Classeng
dc.subjectCardiovascular Diseases/bloodeng
dc.subjectDepressive Disordereng
dc.subjectMajor/bloodeng
dc.subjectMajor/diagnosiseng
dc.subjectDiagnostic and Statistical Manual of Mental Disorderseng
dc.subjectFerritins/bloodeng
dc.subjectFibrinogen/metabolismeng
dc.subjectSeverity of Illness Indexeng
dc.subjectTransferrin/metabolismeng
dc.subject.ddc610 Medizin
dc.titleThe role of the inflammatory markers ferritin, transferrin and fibrinogen in the relationship between major depression and cardiovascular disorders
dc.typeperiodicalPart
dc.subtitleThe German Health Interview and Examination Survey
dc.identifier.urnurn:nbn:de:0257-1009525
dc.identifier.doi10.1111/j.1600-0447.2009.01435.x
dc.identifier.doihttp://dx.doi.org/10.25646/610
local.edoc.container-titleActa Psychiatrica Scandinavica
local.edoc.container-textBaune, B.T., Neuhauser, H., Ellert, U., Berger, K. The role of the inflammatory markers ferritin, transferrin and fibrinogen in the relationship between major depression and cardiovascular disorders - The German Health Interview and Examination Survey (2010) Acta Psychiatrica Scandinavica, 121 (2), pp. 135-142.
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www3.interscience.wiley.com/journal/122467002/abstract?CRETRY=1&SRETRY=0
local.edoc.container-publisher-nameWiley
local.edoc.container-volume121
local.edoc.container-issue2
local.edoc.container-year2009

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