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2006-08-29Zeitschriftenartikel DOI: 10.1017/S0950268806007151
Capture–recapture analysis to estimate the incidence of invasive meningococcal disease in Germany, 2003
dc.contributor.authorSchrauder, Annette
dc.contributor.authorClaus, Hermann
dc.contributor.authorElias, Johannes
dc.contributor.authorVogel, Ulrich
dc.contributor.authorHaas, Walter
dc.contributor.authorHellenbrand, Wiebke
dc.date.accessioned2018-05-07T14:03:28Z
dc.date.available2018-05-07T14:03:28Z
dc.date.created2010-08-05
dc.date.issued2006-08-29none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/rexov7T0MIknQ/PDF/269wPIviqEm5c.pdf
dc.identifier.urihttp://edoc.rki.de/176904/698
dc.description.abstractThe incidence of invasive meningococcal disease (IMD) in Germany in 2003 was estimated by the two-source capture–recapture method. As a unique personal identifier was unavailable, cases with IMD tested at the National Reference Centre for Meningococci (NRZM) were matched with cases reported to the Robert Koch Institute (RKI) through the statutory surveillance system by using demographic and disease-specific variables common to both datasets. The estimated overall incidence was 1.1 IMD cases/100 000 inhabitants, with a sensitivity of ascertainment of 64.8% for NRZM and 89.4% for RKI. Case-fatality rate was estimated at 8.8%. Adjustment for heterogeneity of capture according to age, region and serogroup observed in the NRZM (but not RKI) source had minimal effect on the estimated incidence. The IMD incidence estimated by capture–recapture analysis is thus only slightly higher than through statutory surveillance data. As a degree of positive dependence between the systems cannot be ruled out, this estimate may still be an underestimate. However, under ascertainment appears insufficient to explain the low incidence of IMD in Germany compared to other European countries.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut
dc.subjectAdolescenteng
dc.subjectPreschooleng
dc.subjectNewborneng
dc.subjectHumanseng
dc.subjectFemaleeng
dc.subjectGermany/epidemiologyeng
dc.subjectMaleeng
dc.subjectIncidenceeng
dc.subjectChildeng
dc.subjectAdulteng
dc.subjectInfanteng
dc.subjectMeningococcal Infections/mortalityeng
dc.subjectMortalityeng
dc.subject.ddc610 Medizin
dc.titleCapture–recapture analysis to estimate the incidence of invasive meningococcal disease in Germany, 2003
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-1009772
dc.identifier.doi10.1017/S0950268806007151
dc.identifier.doihttp://dx.doi.org/10.25646/623
local.edoc.container-titleEpidemiology and Infection
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=996344
local.edoc.container-publisher-nameCambridge University Press
local.edoc.container-volume135
local.edoc.container-year2007

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