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2010-11-03Zeitschriftenartikel DOI: 10.1128/JVI.01585-10
African great apes are naturally infected with polyomaviruses closely related to Merkel cell polyomavirus
dc.contributor.authorLeendertz, Fabian
dc.contributor.authorScuda, Nelly
dc.contributor.authorCameron, Kenneth
dc.contributor.authorKidega, Tonny
dc.contributor.authorZuberbühler, Klaus
dc.contributor.authorLeendertz, Siv Aina J.
dc.contributor.authorCouacy-Hymann, Emmanuel
dc.contributor.authorBoesch, Christophe
dc.contributor.authorCalvignac, Sébastien
dc.contributor.authorEhlers, Bernhard
dc.date.accessioned2018-05-07T14:36:36Z
dc.date.available2018-05-07T14:36:36Z
dc.date.created2011-05-18
dc.date.issued2010-11-03none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reIEyoJtpmbZY/PDF/28maqYIXqx7Yg.pdf
dc.identifier.urihttp://edoc.rki.de/176904/876
dc.description.abstractThe oncogenic Merkel cell polyomavirus (MCPyV) infects humans worldwide, but little is known about the occurrence of viruses related to MCPyV in the closest phylogenetic relatives of humans, great apes. We analyzed samples from 30 wild chimpanzees and one captive gorilla and identified two new groups of polyomaviruses (PyVs). These new viruses are by far the closest relatives to MCPyV described to date, providing the first evidence of the natural occurrence of PyVs related to MCPyV in wild great apes. Similar to MCPyV, the prevalence of these viruses is relatively high (>30%). This, together with the fact that humans in West and Central Africa frequently hunt and butcher primates, may point toward further MCPyV-like strains spreading to, or already existing in, our species.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger
dc.subjectDNAeng
dc.subjectMolecular Sequence Dataeng
dc.subjectPhylogenyeng
dc.subjectCluster Analysiseng
dc.subjectPrevalenceeng
dc.subjectAnimalseng
dc.subjectViral/geneticseng
dc.subjectPrimate Diseases/virologyeng
dc.subjectAfricaeng
dc.subjectViral/chemistryeng
dc.subjectGorilla gorilla/virologyeng
dc.subjectPan troglodytes/virologyeng
dc.subjectTumor Virus Infections/virologyeng
dc.subjectSequence Analysis DNAeng
dc.subjectPolyomavirus/classificationeng
dc.subjectPolyomavirus/geneticseng
dc.subjectPolyomavirus/isolation & purificationeng
dc.subjectPolyomavirus Infections/veterinaryeng
dc.subjectPolyomavirus Infections/virologyeng
dc.subjectTumor Virus Infections/veterinaryeng
dc.subject.ddc610 Medizin
dc.titleAfrican great apes are naturally infected with polyomaviruses closely related to Merkel cell polyomavirus
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10014234
dc.identifier.doi10.1128/JVI.01585-10
dc.identifier.doihttp://dx.doi.org/10.25646/801
local.edoc.container-titleJournal of Virology
local.edoc.container-textLeendertz, F.H., Scuda, N., Cameron, K.N., Kidega, T., Zuberbühler, K., Leendertz, S.A.J., Couacy-Hymann, E., Boesch, C., Calvignac, S., Ehlers, B. African great apes are naturally infected with polyomaviruses closely related to Merkel cell polyomavirus (2011) Journal of Virology, 85 (2), pp. 916-924.
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://jvi.asm.org/cgi/content/short/85/2/916
local.edoc.container-publisher-nameAmerican Society for Microbiology
local.edoc.container-volume85
local.edoc.container-issue2
local.edoc.container-year2011

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