Show simple item record

2021-03-15Zeitschriftenartikel
Changes in the prevalence of self-reported sexually transmitted bacterial infections from 2010 and 2017 in two large European samples of men having sex with men–is it time to reevaluate STI-screening as a control strategy?
dc.contributor.authorMarcus, Ulrich
dc.contributor.authorMirandola, Massimo
dc.contributor.authorSchink, Susanne B.
dc.contributor.authorGios, Lorenzo
dc.contributor.authorSchmidt, Axel J.
dc.date.accessioned2022-02-01T08:57:29Z
dc.date.available2022-02-01T08:57:29Z
dc.date.issued2021-03-15none
dc.identifier.other10.1371/journal.pone.0248582
dc.identifier.urihttp://edoc.rki.de/176904/9305
dc.description.abstractBackground/Objectives Many European countries reported increased numbers of syphilis, gonorrhoea and chlamydia diagnoses among men who have sex with men (MSM) in recent years. Behaviour changes and increased testing are thought to drive these increases. Methods In 2010 and 2017, two large online surveys for MSM in Europe (EMIS-2010, EMIS-2017) collected self-reported data on STI diagnoses in the previous 12 months, diagnostic procedures, STI symptoms when testing, number of sexual partners, and sexual behaviours such as condom use during the last intercourse with a non-steady partner in 46 European countries. Multivariate regression models were used to analyse factors associated with diagnoses of syphilis, gonorrhoea/chlamydia, and respective diagnoses classified as symptomatic and asymptomatic. If applicable, they included country-level screening rates. Results Questions on STI diagnoses and sexual behaviours were answered by 156,018 (2010) and 125,837 (2017) participants. Between 2010 and 2017, overall diagnoses with gonorrhoea/chlamydia and syphilis increased by 76% and 83% across countries. Increases were more pronounced for asymptomatic compared to symptomatic infections. The proportion of respondents screened and the frequency of screening grew considerably. Condomless anal intercourse with the last non-steady partner rose by 62%; self-reported partner numbers grew. Increased syphilis diagnoses were largely explained by behavioural changes (including more frequent screening). Gonorrhoea/chlamydia increases were mainly explained by more screening and a change in testing performance. A country variable representing the proportion of men screened for asymptomatic infection was positively associated with reporting symptomatic gonorrhoea/chlamydia, but not syphilis. Discussion/Conclusion The positive association of country-level screening rates with the proportion of symptomatic infections with gonorrhoea/chlamydia may indicate a paradoxical effect of screening on incidence of symptomatic infections. Treatment of asymptomatic men might render them more susceptible to new infections, while spontaneous clearance may result in reduced susceptibility. Before expanding screening programmes, evidence of the effects of screening and treatment is warranted.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectSyphiliseng
dc.subjectHIV diagnosis and managementeng
dc.subjectChlamydia infectioneng
dc.subjectVirus testingeng
dc.subjectChlamydiaeng
dc.subjectMen who have sex with meneng
dc.subjectBlood countseng
dc.subjectSexually transmitted diseaseseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleChanges in the prevalence of self-reported sexually transmitted bacterial infections from 2010 and 2017 in two large European samples of men having sex with men–is it time to reevaluate STI-screening as a control strategy?none
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/9305-1
dc.type.versionpublishedVersionnone
local.edoc.container-titlePLOS ONEnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0248582#:~:text=Between%202010%20and%202017%2C%20overall,frequency%20of%20screening%20grew%20considerably.none
local.edoc.container-publisher-namePLOSnone
local.edoc.container-year2021none
local.edoc.container-firstpage1none
local.edoc.container-lastpage24none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

Show simple item record