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2021-06-02Zeitschriftenartikel
Antimicrobial Resistance and the Spectrum of Pathogens in Dental and Oral-Maxillofacial Infections in Hospitals and Dental Practices in Germany
dc.contributor.authorMeinen, Annika
dc.contributor.authorReuss, Annicka
dc.contributor.authorWillrich, Niklas
dc.contributor.authorFeig, Marcel
dc.contributor.authorNoll, Ines
dc.contributor.authorEckmanns, Tim
dc.contributor.authorAl-Nawas, Bilal
dc.contributor.authorMarkwart, Robby
dc.date.accessioned2022-02-01T13:41:09Z
dc.date.available2022-02-01T13:41:09Z
dc.date.issued2021-06-02none
dc.identifier.other10.3389/fmicb.2021.676108
dc.identifier.urihttp://edoc.rki.de/176904/9319
dc.description.abstractData on microbiological profiles in odontogenic infections are scarce. This study aimed to analyze the spectrum of pathogens and antimicrobial resistance in clinical isolates from dental and oral-maxillofacial clinical settings in Germany. We analyzed 20,645 clinical isolates (dental practices: n = 5,733; hospitals: n = 14,912) from patients with odontogenic infections using data (2012–2019) from the German Antimicrobial-Resistance-Surveillance (ARS) system. A total of 224 different species from 73 genera were found in clinical isolates from dental practices, and 329 different species from 97 genera were identified in isolates from hospital patients. In both hospitals and dental practices Streptococcus spp. (33 and 36%, respectively) and Staphylococcus spp. (21 and 12%, respectively) were the most frequently isolated microorganisms. In Streptococcus spp. isolates from hospitals, penicillin and aminopenicillin resistance proportions were 8.0% (95%CI 4.7–14.9%) and 6.9% (95%CI 4.7–9.9%), respectively. Substantially lower resistance proportions of penicillin and aminopenicillin were observed in dental practices [2.6% (95%CI 1.4–4.7%) and 2.1% (95%CI 1.1–4.0%), respectively]. Among Staphylococcus aureus isolates from hospital patients methicillin resistance proportions were 12.0% (95%CI 9.7–14.8%), which was higher than in isolates from dental practices (5.8% (95%CI 4.1–8.1%)]. High clindamycin and macrolide resistance proportions (>17%) were observed in Streptococcus spp. and Staphylococcus aureus isolates. In Klebsiella spp. isolates carbapenem resistance proportions were <1%. In sum, substantial antibiotic resistance was observed in isolates from odontogenic infections, which calls for strengthened efforts in antibiotic stewardship and infection prevention and control measures in both hospitals and dental practices.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectantimicrobial resistanceeng
dc.subjectAMReng
dc.subjectsurveillanceeng
dc.subjectpathogen spectrumeng
dc.subjectodontogenic infectionseng
dc.subjectdental careeng
dc.subjectAMR in oral-maxillofacial infectionseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleAntimicrobial Resistance and the Spectrum of Pathogens in Dental and Oral-Maxillofacial Infections in Hospitals and Dental Practices in Germanynone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/9319-2
dc.type.versionpublishedVersionnone
local.edoc.container-titleMicrobiologynone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.frontiersin.org/articles/10.3389/fmicb.2021.676108/fullnone
local.edoc.container-publisher-nameFrontiersnone
local.edoc.container-volume12none
local.edoc.container-year2021none
local.edoc.container-firstpage1none
local.edoc.container-lastpage10none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

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