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2021-04-06Zeitschriftenartikel
Seasonality in extra-pulmonary tuberculosis notifications in Germany 2004-2014- a time series analysis
dc.contributor.authorCharles, Tanja
dc.contributor.authorEckardt, Matthias
dc.contributor.authorKaro, Basel
dc.contributor.authorHaas, Walter
dc.contributor.authorKröger, Stefan
dc.date.accessioned2022-02-02T12:36:30Z
dc.date.available2022-02-02T12:36:30Z
dc.date.issued2021-04-06none
dc.identifier.other10.1186/s12889-021-10655-6
dc.identifier.urihttp://edoc.rki.de/176904/9344
dc.description.abstractBackground Seasonality in tuberculosis (TB) has been found in different parts of the world, showing a peak in spring/summer and a trough in autumn/winter. The evidence is less clear which factors drive seasonality. It was our aim to identify and evaluate seasonality in the notifications of TB in Germany, additionally investigating the possible variance of seasonality by disease site, sex and age group. Methods We conducted an integer-valued time series analysis using national surveillance data. We analysed the reported monthly numbers of started treatments between 2004 and 2014 for all notified TB cases and stratified by disease site, sex and age group. Results We detected seasonality in the extra-pulmonary TB cases (N = 11,219), with peaks in late spring/summer and troughs in fall/winter. For all TB notifications together (N = 51,090) and for pulmonary TB only (N = 39,714) we did not find a distinct seasonality. Additional stratified analyses did not reveal any clear differences between age groups, the sexes, or between active and passive case finding. Conclusion We found seasonality in extra-pulmonary TB only, indicating that seasonality of disease onset might be specific to the disease site. This could point towards differences in disease progression between the different clinical disease manifestations. Sex appears not to be an important driver of seasonality, whereas the role of age remains unclear as this could not be sufficiently investigated.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectTuberculosiseng
dc.subjectGermanyeng
dc.subjectSeasonalityeng
dc.subjectTime serieseng
dc.subjectInfectious disease surveillanceeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleSeasonality in extra-pulmonary tuberculosis notifications in Germany 2004-2014- a time series analysisnone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/9344-4
dc.type.versionpublishedVersionnone
local.edoc.container-titleBMC Public Healthnone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-021-10655-6none
local.edoc.container-publisher-nameSpringer Naturenone
local.edoc.container-volume21none
local.edoc.container-year2021none
local.edoc.container-firstpage1none
local.edoc.container-lastpage9none
local.edoc.rki-departmentInfektionsepidemiologienone
dc.description.versionPeer Reviewednone

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