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2022-01-05Zeitschriftenartikel
Exercise and Carotid Properties in the Young–The KiGGS-2 Study
dc.contributor.authorKönigstein, Karsten
dc.contributor.authorBüschges, Julia Charlotte
dc.contributor.authorSarganas, Giselle
dc.contributor.authorKrug, Susanne
dc.contributor.authorNeuhauser, Hannelore
dc.contributor.authorSchmidt-Trucksäss, Arno
dc.date.accessioned2022-02-02T13:34:30Z
dc.date.available2022-02-02T13:34:30Z
dc.date.issued2022-01-05none
dc.identifier.other10.3389/fcvm.2021.767025
dc.identifier.urihttp://edoc.rki.de/176904/9349
dc.description.abstractBackground: Carotid intima-media thickness (cIMT) and stiffness (cS) are predictive markers of early vascular aging and atherosclerotic risk. This study assessed, whether exercise has protective effects on carotid structure and function or on vascular risk in the young. Methods: Volume and change of exercise (recreational and organized sports participation) of German adolescents and young adults was assessed within the prospective population-study KiGGS at KiGGS-Wave-1 (2009–2012) and KiGGS-Wave-2 (2014–2017) using standardized self-reporting questionnaires. CIMT and cS were measured by real-time B-mode ultrasound sequences with semi-automated edge-detection and automatic electrocardiogram-gated quality control in 2,893 participants (14–28 years, 49.6% female). A cumulative index for atherosclerotic risk (CV-R) included z-scores of mean arterial pressure, triglycerides, total/HDL-cholesterol-ratio, body mass index, and HbA1c. Results: At KiGGS-Wave-2 cross-sectional CV-R but not cS and cIMT was lower in all exercise-groups compared to “no exercise” (B = −0.73, 95%-CI = −1.26 to 0.19, p = 0.008). Longitudinal volume of exercise was negatively associated with CV-R (B = −0.37, 95%-CI = −0.74 to 0.00, p = 0.048) but not with cS and cIMT. Cross-sectional relative risk of elevated CV-R but not cS and cIMT was lower in all exercise-groups compared to “no exercise” (RR = 0.80, 95%-CI = 0.66 to 0.98, p = 0.033). High exercise volumes were associated with lower relative risk of elevated CV-R (RR = 0.80, 95%-CI = 0.65–0.97, p = 0.021) and cS in tendency but not with cIMT. Conclusions: Increased levels of exercise are associated with a better cardiovascular risk profile in young individuals, but not with cS and cIMT. Our study confirms previous recommendations on exercise in this age group without demonstrating a clear benefit on surrogate markers of vascular health.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectintima-media thicknesseng
dc.subjectarterial stiffnesseng
dc.subjectatherosclerosiseng
dc.subjectadolescentseng
dc.subjectexerciseeng
dc.subjectcarotid stiffnesseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleExercise and Carotid Properties in the Young–The KiGGS-2 Studynone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/9349-6
dc.type.versionpublishedVersionnone
local.edoc.container-titleCardiovascular Medicinenone
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://www.frontiersin.org/articles/10.3389/fcvm.2021.767025/fullnone
local.edoc.container-publisher-nameFrontiersnone
local.edoc.container-volume8none
local.edoc.container-year2022none
local.edoc.container-firstpage1none
local.edoc.container-lastpage11none
local.edoc.rki-departmentEpidemiologie und Gesundheitsmonitoringnone
dc.description.versionPeer Reviewednone

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