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2011-09-08Zeitschriftenartikel DOI: 10.1371/journal.pone.0024236
Pasteurella multocida Involved in Respiratory Disease of Wild Chimpanzees
dc.contributor.authorKöndgen, Sophie
dc.contributor.authorLeider, Michaela
dc.contributor.authorLankester, Felix
dc.contributor.authorBethe, Astrid
dc.contributor.authorLübke-Becker, Antina
dc.contributor.authorLeendertz, Fabian
dc.contributor.authorEwers, Christa
dc.date.accessioned2018-05-07T14:51:31Z
dc.date.available2018-05-07T14:51:31Z
dc.date.created2011-09-26
dc.date.issued2011-09-08none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reQRFf5W6rLHc/PDF/221S8FNL313A.pdf
dc.identifier.urihttp://edoc.rki.de/176904/957
dc.description.abstractPasteurella multocida can cause a variety of diseases in various species of mammals and birds throughout the world but nothing is known about its importance for wild great apes. In this study we isolated P. multocida from wild living, habituated chimpanzees from Taı¨ National Park, Coˆ te d’Ivoire. Isolates originated from two chimpanzees that died during a respiratory disease outbreak in 2004 as well as from one individual that developed chronic air-sacculitis following this outbreak. Four isolates were subjected to a full phenotypic and molecular characterisation. Two different clones were identified using pulsed field gel electrophoresis. Multi Locus Sequence Typing (MLST) enabled the identification of previous unknown alleles and two new sequence types, ST68 and ST69, were assigned. Phylogenetic analysis of the superoxide dismutase (sodA) gene and concatenated sequences from seven MLST-housekeeping genes showed close clustering within known P. multocida isolated from various hosts and geographic locations. Due to the clinical relevance of the strains described here, these results make an important contribution to our knowledge of pathogens involved in lethal disease outbreaks among endangered great apes.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut
dc.subjectAnimalseng
dc.subjectMolecular Sequence Dataeng
dc.subjectPhylogenyeng
dc.subjectFemaleeng
dc.subjectGenotypeeng
dc.subjectPan troglodytes/microbiologyeng
dc.subjectBacterial Proteins/geneticseng
dc.subjectMicrobial Sensitivity Testseng
dc.subjectPulsed-Fieldeng
dc.subjectDisease Outbreaks/veterinaryeng
dc.subjectMicrobial Viability/drug effectseng
dc.subjectDNA Bacterial/geneticseng
dc.subjectSequence Analysis DNAeng
dc.subjectBacterial Proteins/classificationeng
dc.subjectCote d'Ivoire/epidemiologyeng
dc.subjectDNA Bacterial/chemistryeng
dc.subjectElectrophoresis Geleng
dc.subjectGene Frequencyeng
dc.subjectMonkey Diseases/epidemiologyeng
dc.subjectMonkey Diseases/microbiologyeng
dc.subjectPasteurella Infections/epidemiologyeng
dc.subjectPasteurella Infections/veterinaryeng
dc.subjectPasteurella multocida/classificationeng
dc.subjectPasteurella multocida/geneticseng
dc.subjectPasteurella multocida/isolation & purificationeng
dc.subjectRespiratory Tract Diseases/epidemiologyeng
dc.subjectRespiratory Tract Diseases/veterinaryeng
dc.subjectSuperoxide Dismutase/classificationeng
dc.subjectSuperoxide Dismutase/geneticseng
dc.subject.ddc610 Medizin
dc.titlePasteurella multocida Involved in Respiratory Disease of Wild Chimpanzees
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10015507
dc.identifier.doi10.1371/journal.pone.0024236
dc.identifier.doihttp://dx.doi.org/10.25646/882
local.edoc.container-titlePLoS ONE
local.edoc.container-textKöndgen, S., Leider, M., Lankester, F., Bethe, A., Lübke-Becker, A., Leendertz, F.H., Ewers, C. Pasteurella multocida involved in respiratory disease of wild chimpanzees (2011) PLoS ONE, 6 (9), art. no. e24236.
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0024236
local.edoc.container-publisher-namePublic Library of Science
local.edoc.container-volume6
local.edoc.container-issue9
local.edoc.container-year2011

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