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2022-04-06Zeitschriftenartikel
Non-invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture
dc.contributor.authorPatrono, Livia V.
dc.contributor.authorRöthemeier, Caroline
dc.contributor.authorKouadio, Leonce
dc.contributor.authorCouacy-Hymann, Emmanuel
dc.contributor.authorWittig, Roman M.
dc.contributor.authorCalvignac-Spencer, Sébastien
dc.contributor.authorLeendertz, Fabian H.
dc.date.accessioned2022-05-16T06:10:56Z
dc.date.available2022-05-16T06:10:56Z
dc.date.issued2022-04-06none
dc.identifier.otherhttps://doi.org/10.1111/irv.12984
dc.identifier.urihttp://edoc.rki.de/176904/9717
dc.description.abstractHuman respiratory pathogens have repeatedly caused lethal outbreaks in wild great apes across Africa, leading to population declines. Nonetheless, our knowledge of potential genomic changes associated with pathogen introduction and spread at the human-great ape interface remains sparse. Here, we made use of target enrichment coupled with next generation sequencing to non-invasively investigate five outbreaks of human-introduced respiratory disease in wild chimpanzees living in Taï National Park, Ivory Coast. By retrieving 34 complete viral genomes and three distinct constellations of pneumococcal virulence factors, we provide genomic insights into these spillover events and describe a framework for non-invasive genomic surveillance in wildlife.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectnon-invasive health monitoringeng
dc.subjectpathogen genomicseng
dc.subjectrespiratory diseaseeng
dc.subjectwild great apeseng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleNon-invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capturenone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/9717-2
dc.type.versionpublishedVersionnone
local.edoc.container-titleInfluenza and Other Respiratory Virusesnone
local.edoc.container-issn1750-2659none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://onlinelibrary.wiley.com/doi/10.1111/irv.12984none
local.edoc.container-publisher-nameJohn Wiley & Sonsnone
local.edoc.container-year2022none
local.edoc.container-firstpage1none
local.edoc.container-lastpage4none
dc.description.versionPeer Reviewednone

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