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Browsing by Author "Bagramyan, Karine"

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    • 2016-06-13Zeitschriftenartikel
      N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A 
      Yao, Guorui; Zhang, Sicai; Mahrhold, Stefan; Lam, Kwok-ho; Stern, Daniel; Bagramyan, Karine; Perry, Kay; Kalkum, Markus; Rummel, Andreas; Dong, Min; Jin, Rongsheng
      Botulinum neurotoxin serotype A1 (BoNT/A1), a licensed drug widely used for medical and cosmetic applications, exerts its action by invading motoneurons. Here we report a 2.0-Å-resolution crystal structure of the BoNT/A1 ...
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