Auflistung nach Autor "Kunisch, Ralph"

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2009-02-09Zeitschriftenartikel

Characterisation of porin genes from Mycobacterium fortuitum and their impact on growth

Sharbati, Soroush; Schramm, Kira; Rempel, Sonja; Wang, Hwa; Andrich, Ronny; Tykiel, Verena; Kunisch, Ralph; Lewin, Astrid

Background: Highly pathogenic mycobacteria like Mycobacterium tuberculosis are characterised by their slow growth and their ability to reside and multiply in the very hostile phagosomal environment and a correlation ...
2012-09-11Zeitschriftenartikel

Illegitimate recombination: An efficient method for random mutagenesis in Mycobacterium avium subsp. hominissuis

Khattak, Faisal A.; Kumar, Ashutosh; Kamal, Elisabeth; Kunisch, Ralph; Lewin, Astrid

Background: The genus Mycobacterium (M.) comprises highly pathogenic bacteria such as M. tuberculosis as well as environmental opportunistic bacteria called non-tuberculous mycobacteria (NTM). While the incidence of ...
2012-06-13Zeitschriftenartikel

Mycobacterium tuberculosis DosR Regulon Gene Rv0079 Encodes a Putative, ‘Dormancy Associated Translation Inhibitor (DATIN)’

Kumar, Ashutosh; Majid, Mohammad; Kunisch, Ralph; Rani, Pittu Sandhya; Qureshi, Insaf A.; Lewin, Astrid; Hasnain, Seyed E.; Ahmed, Niyaz

Mycobacterium tuberculosis is a major human pathogen that has evolved survival mechanisms to persist in an immune-competent host under a dormant condition. The regulation of M. tuberculosis metabolism during latent infection ...
2008-06-10Zeitschriftenartikel

The mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG influences various growth characteristics

Lewin, Astrid; Baus, Daniela; Kamal, Elisabeth; Bon, Fabienne; Kunisch, Ralph; Maurischat, Sven; Adonopoulou, Michaela; Eich, Katharina

Background: Pathogenic mycobacteria such as M. tuberculosis, M. bovis or M. leprae are characterised by their extremely slow growth rate which plays an important role in mycobacterial virulence and eradication of the ...
2012-08-03Zeitschriftenartikel

The role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction

Kunisch, Ralph; Kamal, Elisabeth; Lewin, Astrid

Background: Mycobacterium tuberculosis differs from most pathogens in its ability to multiply inside monocytes and to persist during long periods of time within granuloma in a status of latency. A class of proteins ...