2020-10-12Zeitschriftenartikel
Liposomal FRET Assay Identifies Potent Drug‐Like Inhibitors of the Ceramide Transport Protein (CERT)
Samaha, Doaa; Hamdo, Housam H.; Cong, Xiaojing; Schumacher, Fabian; Banhart, Sebastian; Aglar, Öznur; Möller, Heiko M.; Heuer, Dagmar; Kleuser, Burkhard; Saied, Essa M.; Arenz, Christoph
Ceramide transfer protein (CERT) mediates non‐vesicular transfer of ceramide from endoplasmic reticulum to Golgi apparatus and thus catalyzes the rate‐limiting step of sphingomyelin biosynthesis. Usually, CERT ligands are ...