2023-03-22Zeitschriftenartikel
Spreading depolarization and angiographic spasm are separate mediators of delayed infarcts
Horst, Viktor; Kola, Vasilis; Lemale, Coline L.; Major, Sebastian; Winkler, Maren K. L.; Hecht, Nils; Santos, Edgar; Platz, Johannes; Sakowitz, Oliver W.; Vatter, Hartmut; Dohmen, Christian; Scheel, Michael; Vajkoczy, Peter; Hartings, Jed A.; Woitzik, Johannes; Martus, Peter; Dreier, Jens P.
In DISCHARGE-1, a recent Phase III diagnostic trial in aneurysmal subarachnoid haemorrhage patients, spreading depolarization variables were found to be an independent real-time biomarker of delayed cerebral ischaemia. We ...