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Browsing by Author "Kellam, Paul"
Now showing items 1-4 of 4
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2018-05-18ZeitschriftenartikelEasy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver Wymant, Chris; Blanquart, François; Golubchik, Tanya; Gall, Astrid; Bakker, Margreet; Bezemer, Daniela; Croucher, Nicholas J.; Hall, Matthew; Hillebregt, Mariska; Ong, Swee Hoe; Ratmann, Oliver; Albert, Jan; Bannert, Norbert; Fellay, Jacques; Fransen, Katrien; Gourlay, Annabelle; Grabowski, M. Kate; Gunsenheimer-Bartmeyer, Barbara; Günthard, Huldrych F.; Kivelä, Pia; Kouyos, Roger; Laeyendecker, Oliver; Liitsola, Kirsi; Meyer, Laurence; Porter, Kholoud; Ristola, Matti; van Sighem, Ard; Berkhout, Ben; Cornelissen, Marion; Kellam, Paul; Reiss, Peter; Fraser, ChristopheStudying the evolution of viruses and their molecular epidemiology relies on accurate viral sequence data, so that small differences between similar viruses can be meaningfully interpreted. Despite its higher throughput ...
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2017-11-27ZeitschriftenartikelEvaluating the Impact of Functional Genetic Variation on HIV-1 Control McLaren, Paul J.; Pulit, Sara L.; Gurdasani, Deepti; Bartha, Istvan; Shea, Patrick R.; Pomilla, Cristina; Gupta, Namrata; Gkrania-Klotsas, Effrossyni; Young, Elizabeth H.; Bannert, Norbert; Amo, Julia Del; Gill, M. John; Gilmour, Jill; Kellam, Paul; Kelleher, Anthony D.; Sönnerborg, Anders; Zangerle, Robert; Post, Frank A.; Fisher, Martin; Haas, David W.; Walker, Bruce D.; Porter, Kholoud; Goldstein, David B.; Sandhu, Manjinder S.; Fellay, JacquesBackground: Previous genetic association studies of human immunodeficiency virus-1 (HIV-1) progression have focused on common human genetic variation ascertained through genome-wide genotyping. Methods: We sought ...
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2022-03-16ZeitschriftenartikelPhylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load Zhao, Lele; Wymant, Chris; Blanquart, François; Golubchik, Tanya; Gall, Astrid; Bakker, Margreet; Bezemer, Daniela; Hall, Matthew; Hoe Ong, Swee; Albert, Jan; Bannert, Norbert; Fellay, Jacques; Grabowski, M. Kate; Gunsenheimer-Bartmeyer, Barbara; Günthard, Huldrych F.; Kivelä, Pia; Kouyos, Roger D.; Laeyendecker, Oliver; Meyer, Laurence; Porter, Kholoud; van Sighem, Ard; van der Valk, Marc; Berkhout, Ben; Kellam, Paul; Cornelissen, Marion; Reiss, Peter; Fraser, Christophe; Ferretti, Luca; on behalf of the BEEHIVE CollaborationSet-point viral load (SPVL), a common measure of human immunodeficiency virus (HIV)-1 virulence, is partially determined by viral genotype. Epidemiological evidence suggests that this viral property has been under stabilising ...
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2016-01-01ZeitschriftenartikelRapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases Arias, Armando; Watson, Simon J.; Asogun, Danny; Tobin, Ekaete Alice; Lu, Jia; Phan, My V. T.; Jah, Umaru; Wadoum, Raoul Emeric Guetiya; Meredith, Luke; Caddy, Lucy Thorne Sarah; Tarawalie, Alimamy; Langat, Pinky; Dudas, Gytis; Faria, Nuno R.; Dellicour, Simon; Kamara, Abdul; Kargbo, Brima; Kamara, Brima Osaio; Gevao, Sahr; Cooper, Daniel; Newport, Matthew; Kurth, Andreas; Kellam, Paul; Goodfellow, Ian; Cotten, MatthewTo end the largest known outbreak of Ebola virus disease (EVD) in West Africa and to prevent new transmissions, rapid epidemiological tracing of cases and contacts was required. The ability to quickly identify unknown ...