2021-11-02Zeitschriftenartikel
SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase
Choi, Won Young; Kim, Seongok; Aurass, Philipp; Huo, Wenwen; Creasey, Elizabeth A.; Edwards, Marc; Lowe, Martin; Isberg, Ralph R.
Legionella pneumophila grows intracellularly within a replication vacuole via action of Icm/Dot-secreted proteins. One such protein, SdhA, maintains the integrity of the vacuolar membrane, thereby preventing cytoplasmic ...