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Auflistung nach Autor "Bokelmann, Marcel"
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2019-10-11ZeitschriftenartikelDendritic Cells Generated From Mops condylurus, a Likely Filovirus Reservoir Host, Are Susceptible to and Activated by Zaire Ebolavirus Infection Edenborough, Kathryn M.; Bokelmann, Marcel; Lander, Angelika; Couacy-Hymann, Emmanuel; Lechner, Johanna; Drechsel, Oliver; Renard, Bernhard Y.; Radonić, Aleksandar; Feldmann, Heinz; Kurth, Andreas; Prescott, JosephEbola virus infection of human dendritic cells (DCs) induces atypical adaptive immune responses and thereby exacerbates Ebola virus disease (EVD). Human DCs, infected with Ebola virus aberrantly express low levels of the ...
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2020-03-20ZeitschriftenartikelMicrobiomes in the insectivorous bat species Mops condylurus rapidly converge in captivity Edenborough, Kathryn M.; Mu, Andre; Mühldorfer, Kristin; Lechner, Johanna; Lander, Angelika; Bokelmann, Marcel; Couacy-Hymann, Emmanuel; Radonic, AleksandarBats are well known reservoir hosts for RNA and DNA viruses. The use of captive bats in research has intensified over the past decade as researchers aim to examine the virus-reservoir host interface. In this study, we ...
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2021-10-29ZeitschriftenartikelTolerance and Persistence of Ebola Virus in Primary Cells from Mops condylurus, a Potential Ebola Virus Reservoir Bokelmann, Marcel; Vogel, Uwe; Debeljak, Franka; Düx, Ariane; Riesle-Sbarbaro, Silke; Lander, Angelika; Wahlbrink, Annette; Kromarek, Nicole; Neil, Stuart; Couacy-Hymann, Emmanuel; Prescott, Joseph; Kurth, AndreasAlthough there have been documented Ebola virus disease outbreaks for more than 40 years, the natural reservoir host has not been identified. Recent studies provide evidence that the Angolan free-tailed bat (Mops ...
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2020-01-21ZeitschriftenartikelUtility of primary cells to examine NPC1 receptor expression in Mops condylurus, a potential Ebola virus reservoir Bokelmann, Marcel; Edenborough, Kathryn; Hetzelt, Nicole; Kreher, Petra; Lander, Angelika; Nitsche, Andreas; Vogel, Uwe; Feldmann, Heinz; Couacy-Hymann, Emmanuel; Kurth, AndreasThe significance of the integral membrane protein Niemann-Pick C1 (NPC1) in the ebolavirus entry process has been determined using various cell lines derived from humans, non-human primates and fruit bats. Fruit bats have ...