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Auflistung nach Autor "Grunow, Roland"
Anzeige der Publikationen 1-20 von 45
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2022-07-20ZeitschriftenartikelAdaptation of Brucella melitensis Antimicrobial Susceptibility Testing to the ISO 20776 Standard and Validation of the Method Tscherne, Alina; Mantel, Enrico; Boskani, Talar; Budniak, Sylwia; Elschner, Mandy; Fasanella, Antonio; Feruglio, Siri L.; Galante, Domenico; Giske, Christian G.; Grunow, Roland; Henczko, Judit; Hinz, Christin; Iwaniak, Wojciech; Jacob, Daniela; Kedrak-Jablonska, Agnieszka; Jensen, Veronica K.; Johansen, Tone Bjordal; Kahlmeter, Gunnar; Manzulli, Viviane; Matushek, Erika; Melzer, Falk; Nuncio, Maria S.; Papaparaskevas, Joseph; Pelerito, Ana; Solheim, Margrete; Thomann, Susanne; Tsakris, Athanasios; Wahab, Tara; Weiner, Marcin; Zoeller, Lothar; Zange, Sabine; EMERGE AST Working GroupBrucellosis, mainly caused by Brucella (B.) melitensis, is associated with a risk of chronification and relapses. Antimicrobial susceptibility testing (AST) standards for B. melitensis are not available, and the agent is ...
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2013-03-28ZeitschriftenartikelAnthrax among heroin users in Europe possibly caused by same Bacillus anthracis strain since 2000 Grunow, Roland; Klee, Silke; Beyer, W.; George, Maja; Grunow, D.; Barduhn, Anne; Jacob, Daniela; Elschner, M.; Sandven, P.; Kjerulf, A.; Jensen, J. S.; Cai, Wei; Zimmermann, Ruth; Schaade, LarsInjection anthrax was described first in 2000 in a heroin-injecting drug user in Norway. New anthrax cases among heroin consumers were detected in the United Kingdom (52 cases) and Germany (3 cases) in 2009-10. In June ...
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2016-09-08ZeitschriftenartikelBacillus cereus Biovar Anthracis Causing Anthrax in Sub-Saharan Africa—Chromosomal Monophyly and Broad Geographic Distribution Antonation, Kym S.; Grützmacher, Kim; Dupke, Susann; Mabon, Philip; Zimmermann, Fee; Lankester, Felix; Peller, Tianna; Feistner, Anna; Todd, Angelique; Herbinger, Ilka; Nys, Hélène de; Muyembe-Tamfun, Jean-Jacques; Karhemere, Stomy; Wittig, Roman M.; Couacy-Hymann, Emmanuel; Grunow, Roland; Calvignac-Spencer, Sébastien; Corbett, Cindi R.; Klee, Silke; Leendertz, Fabian H.Through full genome analyses of four atypical Bacillus cereus isolates, designated B. cereus biovar anthracis, we describe a distinct clade within the B. cereus group that presents with anthrax-like disease, carrying ...
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2014-11-11ZeitschriftenartikelBenefits of a European project on diagnostics of highly pathogenic agents and assessment of potential “dual use” issues Grunow, Roland; Ippolito, G.; Jacob, Daniela; Sauer, Ursula; Rohleder, Anna; Caro, A. Di; Iacovino, R.Quality assurance exercises and networking on the detection of highly infectious pathogens (QUANDHIP) is a joint action initiative set up in 2011 that has successfully unified the primary objectives of the European Network ...
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2016-08-04ZeitschriftenartikelBrucellosis in a refugee who migrated from Syria to Germany and lessons learnt, 2016 Grunow, Roland; Jacob, Daniela; Klee, Silke; Schlembach, D.; Jackowski-Dohrmann, S.; Loenning-Baucke, V.; Eberspächer, B.; Swidsinski, S.A teenage woman migrating from Syria arrived in May 2015 in Germany. She gave birth to a healthy child in early 2016, but became febrile shortly after delivery. Blood cultures revealed Brucella melitensis. In retrospect, ...
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2021-04-29ZeitschriftenartikelBurkholderia pseudomallei multi-centre study to establish EUCAST MIC and zone diameter distributions and epidemiological cut-off values Karatuna, Onur; Dance, David Allan Brett; Matuschek, Erika; Åhman, Jenny; Turner, Paul; Hopkins, Jill; Amornchai, Premjit; Wuthiekanun, Vanaporn; Cusack, Tomas Paul; Baird, Robert W.; Hennessy, Jann N.; Norton, Robert Edward L.; Armstrong, Mark Robin; Zange, Sabine; Zoeller, Lothar; Wahab, Tara; Jacob, Daniela; Grunow, Roland; Kahlmeter, GunnarObjectives Melioidosis, caused by Burkholderia pseudomallei, requires intensive antimicrobial treatment. However, standardized antimicrobial susceptibility testing (AST) methodology based on modern principles for ...
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2015-04-01ZeitschriftenartikelCapsules, Toxins and AtxA as Virulence Factors of Emerging Bacillus cereus Biovar anthracis Brézillon, Christophe; Haustant, Michel; Dupke, Susann; Corre, Jean-Philippe; Lander, Angelika; Franz, Tatjana; Monot, Marc; Couture-Tosi, Evelyne; Jouvion, Gregory; Leendertz, Fabian; Grunow, Roland; Mock, Michèle E.; Klee, Silke; Goossens, Pierre L.Emerging B. cereus strains that cause anthrax-like disease have been isolated in Cameroon (CA strain) and Côte d’Ivoire (CI strain). These strains are unusual, because their genomic characterisation shows that they belong ...
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2010-09-24ZeitschriftenartikelCharacterization of Yersinia using MALDI-TOF mass spectrometry and chemometrics. Lasch, Peter; Drevinek, Michal; Nattermann, Herbert; Grunow, Roland; Stämmler, Maren; Dieckmann, Ralf; Schwecke, Torsten; Naumann, DieterYersinia are Gram-negative, rod-shaped facultative anaerobes, and some of them, Yersinia enterocolitica, Yersinia pseudotuberculosis, and Yersinia pestis, are pathogenic in humans. Rapid and accurate identification of ...
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2019-05-06ZeitschriftenartikelClinical characteristics in a sentinel case as well as in a cluster of tularemia patients associated with grape harvest Wetzstein, Nils; Kärcher, Iris; Küpper-Tetzel, Claus P.; Kann, Gerrit; Hogardt, Michael; Jozsa, Katalin; Jacob, Daniela; Grunow, Roland; Just-Nübling, Gudrun; Wolf, TimoBackground Tularemia is caused by Francisella tularensis and can occasionally establish foodborne transmission. Methods Patients were identified by active case detection through contact with the treating physicians and ...
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2018-03-14ZeitschriftenartikelConstruction of a New Phage Integration Vector pFIV-Val for Use in Different Francisella Species Tlapák, Hana; Köppen, Kristin; Rydzewski, Kerstin; Grunow, Roland; Heuner, KlausWe recently identified and described a putative prophage on the genomic island FhaGI-1 located within the genome of Francisella hispaniensis AS02-814 (F. tularensis subsp. novicida-like 3523). In this study, we constructed ...
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2012-11-14ZeitschriftenartikelDesinfektion von Persönlicher Schutzausrüstung Methodenentwicklung zur standardisierten Untersuchung der Wirksamkeit von Desinfektionsmitteln auf Oberflächen der Persönlichen Schutzausrüstunggegen Sporen, Viren und Toxine unter praxisnahen Bedingungenund Anwendung der Untersuchungsmethoden am Beispiel von PeressigsäureLemmer, Karin; Roder, Anja; Nattermann, Herbert; Schwebke, Ingeborg; Mielke, Martin; Dorner, Brigitte; Pauli, Georg; Grunow, RolandDie Dekontamination von Persönlicher Schutzausrüstung (PSA) in biologischer Gefahrenlage mit Verdacht auf Kontamination der PSA durch ein hochpathogenes biologisches Agens sollte effektiv, in kurzer Zeit durchführbar ...
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2009-09-30ZeitschriftenartikelDevelopment of Antibodies against Anthrose Tetrasaccharide for Specific Detection of Bacillus anthracis Spores Kühn, Andrea; Kovac, Pavol; Saksena, Rina; Bannert, Norbert; Klee, Silke; Ranisch, Heidrun; Grunow, RolandMethods for the immunological detection of Bacillus anthracis in various environmental samples and the discrimination of B. anthracis from other members of the B. cereus group are not yet well established. To generate ...
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2017-06-21ZeitschriftenartikelDifferential Substrate Usage and Metabolic Fluxes in Francisella tularensis Subspecies holarctica and Francisella novicida Chen, Fan; Rydzewski, Kerstin; Kutzner, Erika; Häuslein, Ina; Schunder, Eva; Wang, Xinzhe; Meighen-Berger, Kevin; Grunow, Roland; Eisenreich, Wolfgang; Heuner, KlausFrancisella tularensis is an intracellular pathogen for many animals causing the infectious disease, tularemia. Whereas F. tularensis subsp. holarctica is highly pathogenic for humans, F. novicida is almost avirulent for ...
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2018-10-11ZeitschriftenartikelDraft Genome Sequence of Bacillus anthracis Strain Sterne 09RA8929 Busch, Anne; Elschner, Mandy Carolina; Jacob, Daniela; Grunow, Roland; Tomaso, H.A Bacillus anthracis vaccine strain (Sterne), used as an attenuated laboratory comparative strain, was sequenced and analyzed. A comparison to assemblies of B. anthracis strain Sterne (NZ_CP009541 and NZ_CP009540) was ...
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2010-04-30ZeitschriftenartikelDrogenkonsum: Bacillus anthracis in Heroin? Bernard, Helen; Faber, Mirko; Grunow, Roland; Bochat, Verena; Görg, AnetteDas Robert-Koch-Institut bittet die Ärzteschaft um erhöhte Aufmerksamkeit bezüglich Haut- oder Weichteilinfektionen bei Heroinkonsumenten, da diese durch den Milzbranderreger verursacht sein könnten.
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2021-11-15ZeitschriftenartikelEpidemiological investigation of a tularaemia outbreak after a hare hunt in Bavaria, Germany, 2018 Böhm, Stefanie; vom Berge, Katharina; Hierhammer, Daniela; Jacob, Daniela; Grunow, Roland; Riehm, Julia M.; Konrad, Regina; Dauer, Marc; Bouschery, Berit; Hossain, Hamid; Schichtl, Elisabeth; Böhmer, Merle M.In November 2018, a tularaemia outbreak occurred in Bavaria, Germany, among participants of a hare hunt and butchery employees handling the hares. We con-ducted an epidemiological outbreak investigation, including a ...
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2011-12-01ZeitschriftenartikelErfahrungen bei der Evaluierung von ABICAP® – Hand-Held-Testkits zum Nachweis von Francisella tularensis und Ebolavirus Grunow, Roland; Lucht, Andreas; Porsch-Özcürümez, MustafaIn unseren Untersuchungen haben wir das säulenchromatographische Verfahren ABICAP® (Antibody Immuno Column for Analytical Processes) der Firma Senova, Jena, hinsichtlich seiner Eignung als Ultraschnelltest für den Nachweis ...
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2020-02-17ZeitschriftenartikelEvaluation of Sporicidal Disinfectants for the Disinfection of Personal Protective Equipment During Biological Hazards Papp, Stefanie; Kimmerl, Katharina; Gatz, Jacob; Laue, Michael; Grunow, Roland; Kaspari, OliverA fast, effective, and safe disinfection of personal protective equipment (PPE) is vitally important for emergency forces involved in biological hazards. This study aimed to investigate a broad range of disinfectants to ...
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2012-06-28ZeitschriftenartikelFatal anthrax infection in a heroin user from southern Germany, June 2012 Holzmann, Thomas; Frangoulidis, D.; Simon, M.; Noll, P.; Schmoldt, S.; Hanczaruk, M.; Grass, G.; Pregler, M.; Sing, A.; Hörmansdorfer, S.; Bernard, Helen; Grunow, Roland; Zimmermann, Ruth; Schneider-Brachert, W.; Gessner, A.; Reischl, UdoBlood cultures from a heroin user who died in June 2012, a few hours after hospital admission, due to acute septic disease, revealed the presence of Bacillus anthracis. This report describes the extended diagnosis by ...
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2013-01-18ZeitschriftenartikelFirst indication for a functional CRISPR/Cas system in Francisella tularensis Schunder, Eva; Rydzewski, Kerstin; Grunow, Roland; Heuner, KlausFrancisella tularensis is a zoonotic agent and the subspecies novicida is proposed to be a water-associated bacterium. The intracellular pathogen F. tularensis causes tularemia in humans and is known for its potential to ...